- Tight Control of Gouty Arthritis Compared to Usual Care — Recruiting • Non-phase study • Rheumatology • NCT05507723.
- Patient-led urate monitoring with smartphone support reduces gout flares compared to standard treatment approaches.
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- Connecting this trial to nearby guidelines, Drug Science and education.
Gout is caused by a reaction to urate crystals that results in attacks of severe joint pain. Medicines that lower urate levels can prevent gout flares, however it takes time for this benefit to be felt, and paradoxically starting treatment with large doses of urate lowering treatment risks provoking attacks of gout. Medical guidelines disagree on the best way to overcome these challenges with many recommending medicine dose adjustment based on regular urate testing but a general practice guideline suggesting more simply increasing the medicine dose in those patients that…