Neurology
Neurology guidelines, trial updates, mechanisms and education across headache, neuroinflammation, movement disorders and specialist prescribing.
Latest Guidelines
Software with artificial intelligence (AI)-derived algorithms to help interpret electroencephalograms (EEGs) for suspected epilepsy: early-use assessment
AI-assisted EEG interpretation software can support clinicians in identifying abnormalities suggestive of epilepsy, but should complement rather than replace expert clinical review—use as a triage or…
Mirdametinib for treating symptomatic and inoperable plexiform neurofibromas associated with neurofibromatosis type 1 in people 2 to 17 years
Mirdametinib is indicated for symptomatic and inoperable plexiform neurofibromas in children aged 2-17 years with neurofibromatosis type 1 (NF1); confirm diagnosis and operability status before initiating…
Atogepant for treating migraine
Atogepant is recommended as a preventive treatment option for episodic migraine in adults; consider initiating in patients with ≥4 migraine days per month who have failed…
Oxybutynin hydrochloride for managing neurogenic detrusor overactivity in people 6 years and over with spinal cord injury or spina bifida (terminated appraisal)
Oxybutynin is effective for neurogenic detrusor overactivity in patients aged 6+ years with spinal cord injury or spina bifida—consider as first-line antimuscarinic therapy for managing symptoms…
2022 EAN/EFNS Guidelines on Dementia Diagnosis and Management
This EAN guideline addresses 2022 EAN/EFNS Guidelines on Dementia Diagnosis and Management in Neurology. Use it to review current recommendation wording, eligibility criteria, and implementation considerations…
2023 EAN Guidelines on the Management of Multiple Sclerosis
This EAN guideline addresses 2023 EAN Guidelines on the Management of Multiple Sclerosis in Neurology. Use it to review current recommendation wording, eligibility criteria, and implementation…
Trial Radar
REAL-MS: Observational Database Study of AHSCT and MS Therapies
Multiple sclerosis (MS) is a condition in which the immune system damages the brain and spinal cord. Treatments…
TrialAn Observational Study of Epilepsy: Biology and Outcomes Using Real-world Data
Study collecting blood samples and routine clinical data from people with epilepsy to identify patterns in causes, genetics,…
PHASE2Prevent Cognitive Decline in GBA-associated Parkinson’s Disease
Treatment being tested: Prasinezumab, a monoclonal antibody, is being evaluated for its ability to slow or prevent cognitive…
NAMediPD: An Online Mediterranean Diet Program for People Living With Parkinson’s Disease
What is being tested: MediPD, an online Mediterranean diet intervention programme designed specifically for people living with Parkinson's…
Clinical News
Diabetes and ADHD drugs to be tested on Alzheimer’s patients in new study
Diabetes and ADHD medications are being simultaneously tested as potential Alzheimer's treatments, potentially accelerating drug development timelines for…
21 Oct 2026Christina Applegate says she was wrongly diagnosed with MS
Diagnostic delays in MS remain a clinical concern: Applegate's five-year misdiagnosis highlights the importance of rigorous diagnostic criteria…
05 Oct 2026Nobel Prize awarded for revealing inner workings of the brain
Karl Deisseroth, Peter Hegemann, and Georg Nagel have been awarded the Nobel Prize for developing optogenetics, a technique…
22 Sep 2026Sisters with life-limiting condition taking NHS fight to Parliament
Two sisters with life-limiting neurological condition are escalating NHS access dispute to parliamentary level, highlighting potential gaps in…
Relevant Mechanisms
CGRP Pathway — Migraine
CGRP Pathway — Migraine is a clinically relevant Drug Science explainer. Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide…
MechanismDopamine D2 Receptor
Dopamine D2 Receptor is a clinically relevant Drug Science explainer. Dopamine (DA) is a monoamine neurotransmitter with distinct functional roles…
MechanismS1P Receptor Modulation — MS/IBD
S1P Receptor Modulation — MS/IBD is a clinically relevant Drug Science explainer. Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite generated…
MechanismSerotonin/Noradrenaline Reuptake
Serotonin/Noradrenaline Reuptake is a clinically relevant Drug Science explainer. Serotonin (5-hydroxytryptamine, 5-HT) and noradrenaline (norepinephrine, NA) are monoamine neurotransmitters with…
CPD, Podcasts & Webinars
Follow Neurology safety updates
Get MHRA safety alerts and clinically relevant updates for this specialty in your ClinicaliQ digest.
Follow Neurology
Choose guideline, trial, Drug Science and education updates for this specialty.