Respiratory / COPD / Asthma
Respiratory guidelines, trial intelligence, inhaled and biologic therapy mechanisms, and education across asthma, COPD and severe respiratory disease.
Latest Guidelines
Digital technologies to support self-management of asthma: early-use assessment
Use digital asthma self-management tools (apps, web platforms, wearables) as adjuncts to standard care to help patients monitor symptoms, track triggers, and improve medication adherence—particularly beneficial…
Digital technologies for applying algorithms to spirometry to support asthma and COPD diagnosis in primary care and community diagnostic centres: early-use assessment
Digital spirometry algorithms can improve diagnostic accuracy for asthma and COPD in primary care and community diagnostic centres, potentially reducing unnecessary referrals to secondary care and…
GOLD 2025 Report: Global Strategy for Prevention, Diagnosis and Management of COPD
GOLD 2025 updates COPD diagnosis criteria: spirometry FEV1/FVC
GINA 2024 Report: Global Strategy for Asthma Management and Prevention
GINA 2024 reinforces no SABA-only treatment for any asthma severity: all patients should receive ICS-containing controller therapy or ICS-formoterol MART as first-line to reduce exacerbation risk…
2021 ESCMID Guidelines for the Management of Community-acquired Pneumonia
This ESCMID guideline addresses 2021 ESCMID Guidelines for the Management of Community-acquired Pneumonia in Respiratory / COPD / Asthma. Use it to review current recommendation wording,…
2023 ERS Guidelines on Sleep-disordered Breathing
This ERS guideline addresses 2023 ERS Guidelines on Sleep-disordered Breathing in Respiratory / COPD / Asthma. Use it to review current recommendation wording, eligibility criteria, and…
Trial Radar
A Two-part Study to Investigate the Effects in Adults of Two Doses of Golexanolone in Patients With Primary Biliary Cholangitis (PBC) With Fatigue and Cognitive Dysfunction
The present phase 1b/2 randomised, double-blind, placebo-controlled, two-part study is designed to evaluate the safety, tolerability, pharmacokinetic characteristics…
NAChronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System (NAVIGATE)
The purpose of this research study is to determine if the Enterra® Therapy System can decrease nausea and…
TrialHealth Impact of Non-Tuberculous Mycobacteria Pulmonary Disease (NTM-PD)
Nontuberculous mycobacteria (NTM) are environmental organisms found in soil and water. The majority do not cause human disease.…
NAClosed-loop TMS for Tremor
What is being tested: Phase-locked transcranial magnetic stimulation (TMS) delivered in synchronisation with tremor oscillations as a non-invasive…
Clinical News
How is Keir Starmer getting on with his pledges to deliver change?
I appreciate you've provided a political news article, but this isn't health/medical news suitable for UK doctors. The…
23 Apr 2026‘I gave up my job due to the stress of my child’s food allergies’
Parental burden of food allergies: Severe childhood food allergies can create such significant psychological stress that parents may…
23 Apr 2026‘My baby scratches and scratches’: Families say their homes are making their children sick
Temporary housing conditions are contributing to increased rates of childhood skin conditions (notably atopic dermatitis), with families reporting…
21 Apr 2026Rogue sperm donor who says he’s fathered 180 children won’t be on child’s birth certificate
A rogue sperm donor case highlights the legal vulnerability of recipients using unregulated private donation arrangements, where donors…
Relevant Mechanisms
Beta-2 Adrenergic and Muscarinic Receptors — COPD/Asthma
Beta-2 Adrenergic and Muscarinic Receptors — COPD/Asthma is a clinically relevant Drug Science explainer. Bronchodilation in obstructive airway disease is…
MechanismCFTR Modulation
CFTR Modulation is a clinically relevant Drug Science explainer. Cystic fibrosis (CF) is caused by mutations in the CFTR gene…
MechanismEGFR Pathway
EGFR Pathway is a clinically relevant Drug Science explainer. The epidermal growth factor receptor (EGFR/ErbB1/HER1) is a transmembrane receptor tyrosine…
MechanismIL-4/IL-13 Axis
IL-4/IL-13 Axis is a clinically relevant Drug Science explainer. Interleukin-4 (IL-4) and interleukin-13 (IL-13) are hallmark type 2 cytokines produced…
MechanismIL-5 Pathway — Severe Eosinophilic Asthma
IL-5 Pathway — Severe Eosinophilic Asthma is a clinically relevant Drug Science explainer. Interleukin-5 (IL-5) is the principal cytokine governing…
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