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MHRA • NHS England • NICE • UKHSA

Clinical News & Alerts

225+ sourced updates — safety alerts, regulatory decisions and NHS England announcements, verified for UK clinicians.

MHRA Safety Alert NHS England NICE Update UKHSA
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Clinical News

Latest Alerts & Updates

⚠️ Safety Alert
MHRA
Letters and medicine recalls sent to healthcare professionals in April 2024
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices, and information about the publication of…
29 May 2024 View brief →
⚠️ Safety Alert
MHRA Mental Health / Psychiatry
Finasteride: reminder of the risk psychiatric side effects and of sexual side effects (which may persist after discontinuation of treatment)
Finasteride: reminder of the risk psychiatric side effects and of sexual side ef...
29 Apr 2024 View brief →
⚠️ Safety Alert
MHRA Mental Health / Psychiatry
Montelukast: reminder of the risk of neuropsychiatric reactions
Healthcare professionals prescribing montelukast should be alert to the risk of neuropsychiatric reactions in all patients including children and adolescents. Reported neuropsychiatric…
29 Apr 2024 View brief →
⚠️ Safety Alert
MHRA
Letters and medicine recalls sent to healthcare professionals in March 2024
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. This update is best treated as…
29 Apr 2024 View brief →
⚠️ Safety Alert
MHRA
Letters and medicine recalls sent to healthcare professionals in February 2024
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. This update is best treated as…
27 Mar 2024 View brief →
⚠️ Safety Alert
MHRA
Codeine linctus (codeine oral solutions): reclassification to prescription-only medicine
Advice for healthcare professionals on the reclassification of codeine linctus to a prescription-only medicine (POM), following a public consultation. This update is…
20 Feb 2024 View brief →
⚠️ Safety Alert
MHRA
Pseudoephedrine: very rare risk of posterior reversible encephalopathy syndrome (PRES) and reversible cerebral vasoconstriction syndrome (RCVS)
There have been very rare reports of posterior reversible encephalopathy syndrome (PRES) and reversible cerebral vasoconstriction syndrome (RCVS) with pseudoephedrine. This update…
20 Feb 2024 View brief →
⚠️ Safety Alert
MHRA
Letters and medicine recalls sent to healthcare professionals in January 2024
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. This update is best treated as…
20 Feb 2024 View brief →
⚠️ Safety Alert
MHRA Women's Health
Valproate (Belvo, Convulex, Depakote, Dyzantil, Epilim, Epilim Chrono or Chronosphere, Episenta, Epival, and Syonell▼): new safety and educational materials to support regulatory measures in men and women under 55 years of age
Valproate (Belvo, Convulex, Depakote, Dyzantil, Epilim, Epilim Chrono or Chronos...
22 Jan 2024 View brief →
⚠️ Safety Alert
MHRA
Fluoroquinolone antibiotics: must now only be prescribed when other commonly recommended antibiotics are inappropriate
Systemic fluoroquinolones must now only be prescribed when other commonly recommended antibiotics are inappropriate. This follows a review by the MHRA which…
22 Jan 2024 View brief →