ClinicaliQ Trial Snapshot
- A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer — Recruiting • Phase II • Oncology • NCT06792695.
- What is being tested: Novel therapeutic interventions and their combinations for colorectal cancer treatment, with primary focus on evaluating safety profiles and clinical efficacy in this patient population.
- Patient eligibility overview: Participants with confirmed colorectal cancer diagnosis are eligible; specific inclusion criteria regarding disease stage, prior treatment history, and performance status would be detailed in the full protocol.
Use This Page For
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying
The main purpose of this study is to evaluate the safety and efficacy of novel study interventions and combinations in participants with Colorectal Cancer (CRC).
Eligibility Snapshot
- Overall Inclusion Criteria: * Histopathologically confirmed colorectal adenocarcinoma. * Provision of FFPE tumor sample collected as per SoC. * Presence of measurable disease by RECIST 1.1 criteria. * ECOG performance status of 0 or 1. * Life expectancy ≥ 12 weeks at the time of screening. Substudy Inclusion Criteria: * No radiological evidence of liver metastasis. * No prior systemic therapy for mCRC, except for neoadjuvant/adjuvant chemotherapy where, > 6 months have elapsed between completion of therapy and documented date of diagnosis of recurrent or metastatic disease. * Known pMMR/MSS status (only pMMR/MSS mCRC allowed). * Adequate organ and bone marrow function * Body weight > 35 kg at screening and at randomization. * Contraceptive use by participants should be consistent with local regulations regarding the methods of contraception for those participating in clinical studies. Overall
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.