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Clinical Trial ● Currently Recruiting Phase I / Phase II NCT04176198

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis — Recruiting • Phase I / Phase II • NCT04176198.

📅 14 Apr 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase I / Phase II
NCT ID
NCT04176198
Start
2019-12-16
Completion
2027-04-30
ClinicaliQ Trial Snapshot
  • A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis — Recruiting • Phase I / Phase II • NCT04176198.
  • Early-stage trial testing a new oral drug (nuvisertib) for safety and effectiveness in myelofibrosis patients.

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  • Quick orientation before opening the registry record.
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What This Trial Is Studying

This study is a Phase 1/2, multicenter, dose-escalation, open-label trial to assess safety, tolerability, pharmacokinetics and pharmacodynamics of nuvisertib (TP-3654) in patients with intermediate or high-risk primary or secondary MF. Conditions: Myelofibrosis Interventions: Nusivertib, Ruxolitinib, Momelotinib Lead Sponsor: Sumitomo Pharma America, Inc. Planned Enrollment: 240 participants

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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