- A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis — Recruiting • Phase I / Phase II • NCT04176198.
- Early-stage trial testing a new oral drug (nuvisertib) for safety and effectiveness in myelofibrosis patients.
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This study is a Phase 1/2, multicenter, dose-escalation, open-label trial to assess safety, tolerability, pharmacokinetics and pharmacodynamics of nuvisertib (TP-3654) in patients with intermediate or high-risk primary or secondary MF. Conditions: Myelofibrosis Interventions: Nusivertib, Ruxolitinib, Momelotinib Lead Sponsor: Sumitomo Pharma America, Inc. Planned Enrollment: 240 participants