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Clinical Trial Active — Not Recruiting Phase II NCT05490446

A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)

A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS) — Active Not Recruiting • Phase II • NCT05490446.

📅 24 Apr 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase II
NCT ID
NCT05490446
Start
2022-11-07
Completion
2026-03-17
ClinicaliQ Trial Snapshot
  • A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS) — Active Not Recruiting • Phase II • NCT05490446.
  • A trial testing whether tebapivat reduces blood transfusion needs in patients with low-risk bone marrow disorders.

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What This Trial Is Studying

This purpose of this study is to establish proof of concept of tebapivat in participants with LR-MDS in Phase 2a and to evaluate the effect of tebapivat on transfusion independence (TI) in participants with LR-MDS in phase 2b. Conditions: Myelodysplastic Syndromes Interventions: Tebapivat Lead Sponsor: Agios Pharmaceuticals, Inc. Planned Enrollment: 87 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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