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Clinical Trial Active — Not Recruiting Phase IV NCT03953300

Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics

Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics — Active Not Recruiting • Phase IV • Respiratory / COPD / Asthma • NCT03953300.

📅 05 May 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase IV
NCT ID
NCT03953300
Start
2019-10-08
Completion
2026-10-19
ClinicaliQ Trial Snapshot
  • Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics — Active Not Recruiting • Phase IV • Respiratory / COPD / Asthma • NCT03953300.
  • Benralizumab improves lung structure and function in severe eosinophilic asthma poorly controlled by standard inhalers.

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What This Trial Is Studying

The purpose of the study is to evaluate effect of benralizumab on structural and lung function changes in severe eosinophilic asthmatics. Changes will be assessed over 48 week treatment period in patients with persistent symptoms despite standard therapy of inhaled corticosteroids (ICS) plus long acting B2-agonist (LABA) with or without additional controller medication. Patients who complete treatment will enter 4 weeks follow-up period. Conditions: Asthma Interventions: Benralizumab, Placebo Lead Sponsor: AstraZeneca Planned Enrollment: 75 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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