ClinicaliQ Trial Snapshot
- Capillary OGTT Study — Recruiting • Respiratory / COPD / Asthma • NCT06815081.
- What is being tested: Capillary (fingerprick) oral glucose tolerance testing (OGTT) as an alternative to venous blood sampling for identifying stage 2 type 1 diabetes in at-risk individuals before symptom onset.
- Patient eligibility overview: Children under 15 years of age at risk of type 1 diabetes, including those with genetic susceptibility or autoimmune markers indicating pre-symptomatic disease stages.
Use This Page For
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying
Type 1 diabetes (T1D) is a chronic condition, affecting 1 in 490 children under the age of 15 years. It is caused by the immune system damaging the pancreas, the organ which makes insulin. T1D has recognised stages before symptoms develop, providing an opportunity for early diagnosis, education and treatment which may delay the onset of symptoms. Type 2 diabetes (T2D) is also a chronic condition where the body cannot make enough insulin, or cannot respond to the insulin properly. It is usually related to obesity, rather than an immune…
Eligibility Snapshot
- : Cohort 1 * Willing and able to give informed consent for participation, or assent with parental consent * Aged < 18 years old * Able to consume oral glucose drink within 10 minutes * Undergoing an OGTT, or consent to have one Cohort 2 * Positive for two or more islet autoantibodies at any time * Willing and able to give informed consent for participation, or assent with parental consent * Aged < 18 years old * Able to consume oral glucose drink within 10 minutes CGM sub-study * Willing and able to give informed consent for participation, or assent with parental consent * Aged < 18 years old * Able to consume oral glucose drink within 10 minutes * Confirmed to have stage 1, 2 or 3 T1D * Participation in Cohort 1 Qualitative sub-study * Willing and able to give informed consent for participation, or assent with parental consent Then EITHER * A young person positive for two or more islet autoantibodies (15 years old and above) at any time, or parent of a young person who has experienced a metabolic test e.g. OGTT OR * A healthcare professional involved in delivering metabolic testing Cohort 3…
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.