ClinicaliQ Trial Snapshot
- Clinical Antenatal Randomised Study to CharactErise Key Roles of TetrahydroFOLate in HyperTensive Pregnancies — Recruiting • Non-phase study • Cardiology / Cardiovascular • NCT05434195.
- What is being tested: The role of tetrahydrofolate (active folate) supplementation in reducing adverse outcomes in pregnant women with hypertension, investigating whether enhanced folate metabolism improves maternal and fetal health.
- Patient eligibility overview: Pregnant women with hypertensive disorders (gestational hypertension, pre-eclampsia, or chronic hypertension), recruited during pregnancy to receive either active folate supplementation or standard care.
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What This Trial Is Studying
Study background High blood pressure during pregnancy is a worldwide health problem that can be dangerous to mothers and commonly causes premature birth and small babies. There is also growing evidence that mothers who suffer from high blood pressure in pregnancy, and their babies, have a higher risk of high blood pressure and cardiovascular disease later in life. Previous studies have revealed detrimental changes in the structure and function of the heart and blood vessels of mothers, and their babies, who experience this common complication. These changes may explain their…
Eligibility Snapshot
- (Preeclampsia individuals): * Diagnosed with preeclampsia, as defined in Section 8.1, at
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.