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Clinical Trial ● Currently Recruiting NCT06188065

Eosinopenia in Severe COPD Exacerbation

Eosinopenia in Severe COPD Exacerbation — Recruiting • Respiratory / COPD / Asthma • NCT06188065.

📅 14 Apr 2026 ⏱ 2 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
NCT ID
NCT06188065
Sponsor
Northumbria Healthcare NHS Foundation Trust
Start
2024-01-22
ClinicaliQ Trial Snapshot
  • Eosinopenia in Severe COPD Exacerbation — Recruiting • Respiratory / COPD / Asthma • NCT06188065.
  • What is being tested: This observational study investigates the causes and recovery patterns of eosinopenia (abnormally low blood eosinophil counts) in patients hospitalised with severe COPD exacerbations, identifying independent factors associated with this condition.
  • Patient eligibility overview: The study includes adults admitted to hospital with severe COPD exacerbations who have documented baseline eosinophil counts during stable disease, allowing comparison of acute versus baseline measurements.
Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

The goals of this observational study are to identify factors independently associated with admission eosinopenia in patients with a severe exacerbation of chronic obstructive pulmonary disease (COPD) and to determine when blood eosinophil count (BEC) will recover to baseline stable state in patients who are admitted to hospital with a severe exacerbation of COPD and associated eosinopenia. The main aims of the study are to: 1. Identify demographic, physiological and clinical factors independently associated with admission eosinopenia in patients with a severe exacerbation of COPD 2. Assess the time to…

Eligibility Snapshot
  • : * Admitted to hospital with primary clinical diagnosis of exacerbation of COPD* * Smoking history of at least 10 pack years * Airflow obstruction: FEV1/FVC ratio < 0.7 confirmed on historic or inpatient spirometry * Capacity to give informed consent to participate

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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