- Eosinopenia in Severe COPD Exacerbation — Recruiting • Respiratory / COPD / Asthma • NCT06188065.
- What is being tested: This observational study investigates the causes and recovery patterns of eosinopenia (abnormally low blood eosinophil counts) in patients hospitalised with severe COPD exacerbations, identifying independent factors associated with this condition.
- Patient eligibility overview: The study includes adults admitted to hospital with severe COPD exacerbations who have documented baseline eosinophil counts during stable disease, allowing comparison of acute versus baseline measurements.
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
The goals of this observational study are to identify factors independently associated with admission eosinopenia in patients with a severe exacerbation of chronic obstructive pulmonary disease (COPD) and to determine when blood eosinophil count (BEC) will recover to baseline stable state in patients who are admitted to hospital with a severe exacerbation of COPD and associated eosinopenia. The main aims of the study are to: 1. Identify demographic, physiological and clinical factors independently associated with admission eosinopenia in patients with a severe exacerbation of COPD 2. Assess the time to…
- : * Admitted to hospital with primary clinical diagnosis of exacerbation of COPD* * Smoking history of at least 10 pack years * Airflow obstruction: FEV1/FVC ratio < 0.7 confirmed on historic or inpatient spirometry * Capacity to give informed consent to participate
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.