- GEneRating Mucosal Immunity After INfluenzA Infection and Vaccination in Lung and Lymphoid TissuE — Recruiting • Non-phase study • Respiratory / COPD / Asthma • NCT06620185.
- Sponsor: Imperial College London.
Verify eligibility, endpoints and current status on the original source registry before acting on this summary.
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
This experimental medicine study aims to compare immune responses in healthy adult volunteers aged 18-55 years against influenza vaccination and infection in the upper and lower respiratory tract, following administration of a live-attenuated influenza vaccine delivered by nasal spray versus influenza A (H3N2) viral challenge.
- : * Adults aged between 18-55 years inclusive * Sero-suitable as defined by a serum micro-neutralisation titre
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.