ClinicaliQ Trial Snapshot
- Graft Failure and Consequences of Coronary Artery Bypass Graft Surgery — Recruiting • Cardiology / Cardiovascular • NCT06800430.
- What is being tested: This research investigates graft failure mechanisms in coronary artery bypass graft (CABG) surgery, examining why arterial and venous grafts used to bypass coronary blockages deteriorate over time and the clinical consequences of this failure.
- Patient eligibility overview: The trial involves patients undergoing CABG surgery who receive grafts to circumvent coronary artery disease, likely stratified by graft type (arterial versus venous) and follow-up timeframes to assess long-term patency and failure rates.
Use This Page For
- Quick orientation before opening the registry record.
- Checking recruitment status, phase and sponsor at a glance.
- Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying
Coronary artery bypass graft (CABG) surgery is the commonest type of heart operation performed. During this, arteries or veins (termed 'grafts') are used to supply blood around blockages within the blood vessels that supply the heart. Unfortunately, these grafts can sometimes fail, and patients can also experience complications like heart attacks and strokes, after surgery. It is known that vein grafts are more likely to narrow over time. Additionally, treating vein graft failure is very challenging, as repeat surgery is riskier and procedures to stent open the veins can also…
Eligibility Snapshot
- : Cohort 1: Patients undergoing CABG surgery * Males and females over 18 years of age * Patients undergoing CABG surgery for multivessel coronary artery disease, who receive at least one saphenous vein graft Cohort 2: Patients with symptomatic saphenous vein graft vasculopathy * Males and females over 18 years of age * Patients who underwent CABG surgery ≥ 5 years prior to recruitment for multivessel disease and received 2 or more saphenous vein grafts * Referred for invasive coronary angiography due to recurrent symptoms and with a high suspicion of graft vasculopathy
Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.