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Clinical Trial ● Currently Recruiting Phase III NCT03955445

Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN — Recruiting • Phase III • NCT03955445.

📅 14 Apr 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase III
NCT ID
NCT03955445
Sponsor
Novartis Pharmaceuticals
Start
2019-10-03
ClinicaliQ Trial Snapshot
  • Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN — Recruiting • Phase III • NCT03955445.
  • What is being tested: Long-term efficacy, safety and tolerability of iptacopan, a Factor B inhibitor targeting the alternative complement pathway, in patients with C3 glomerulopathy (C3G) or idiopathic immune-complex membranoproliferative glomerulonephritis (IC-MPGN).
  • Patient eligibility overview: Subjects with confirmed C3G or IC-MPGN who have completed a preceding iptacopan trial; this is an open-label extension study allowing continued access to treatment for responders and those who may benefit from ongoing therapy.
Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

This is an open-label extension study to evaluate the long-term efficacy, safety and tolerability of iptacopan in subjects with C3 glomerulopathy or idiopathic immune-complex-membranoproliferative glomerulonephritis

Eligibility Snapshot
  • : - Patients must have completed the treatment period of the CLNP023X2202, CLNP023B12301 or CLNP023B12302 study on study drug

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
View Trial ↗
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