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Clinical Trial ● Currently Recruiting Phase II NCT06989359

Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease

Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease — Recruiting • Phase II • NCT06989359.

📅 22 Apr 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase II
NCT ID
NCT06989359
Sponsor
ADARx Pharmaceuticals, Inc.
Start
2025-08-28
ClinicaliQ Trial Snapshot
  • Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease — Recruiting • Phase II • NCT06989359.
  • Drug being tested: ADX-038, a novel therapeutic agent targeting complement-mediated pathways, is being evaluated for safety, efficacy, and how the body processes and responds to the drug (PK/PD) in adult patients with complement-mediated kidney diseases.
  • Patient eligibility: The study focuses on adult patients with confirmed complement-mediated kidney disease; specific inclusion/exclusion criteria would determine baseline kidney function, disease activity, and prior treatment requirements.
Use This Page For
  • Quick orientation before opening the registry record.
  • Checking recruitment status, phase and sponsor at a glance.
  • Connecting this trial to nearby guidelines, Drug Science and education.
What This Trial Is Studying

This Phase 2 study is designed to assess the safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of ADX-038 in adults with complement-mediated kidney diseases.

Eligibility Snapshot
  • : * Mean eGFR greater than or equal to 30 mL/min/1.73m2 * Clinical evidence of active kidney disease * Treated with supportive care including an ACE inhibitor or ARB if applicable * Willing to receive required vaccinations * Primary diagnosis of IgAN, C3G or IC-MPGN confirmed by a kidney biopsy

Use the source registry for the full inclusion and exclusion criteria before discussing referral or enrolment.

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
View Trial ↗
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