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Clinical Trial Active — Not Recruiting Phase I NCT06545942

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors — Active Not Recruiting • Phase I • Oncology • NCT06545942.

📅 17 Apr 2026 ⏱ 1 min read
Active — Not Recruiting
Check the registry for current status and eligibility criteria.
Status
Active — Not Recruiting
Phase
Phase I
NCT ID
NCT06545942
Start
2024-08-13
Completion
2027-05-31
ClinicaliQ Trial Snapshot
  • Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors — Active Not Recruiting • Phase I • Oncology • NCT06545942.
  • A study testing a new oral drug (MOMA-313) in patients with advanced cancers, assessing safety, dosage, and effectiveness alone or combined.

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What This Trial Is Studying

This Phase 1, multi-center, open-label, dose escalation and dose optimization study is designed to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and preliminary clinical activity of MOMA-313 administered orally as a single agent or combination therapy in patients with homologous recombinant deficient solid tumors. Conditions: Advanced Solid Tumor, Metastatic Solid Tumor, Prostate Cancer, Pancreas Cancer, Breast Cancer, Ovarian Cancer, Homologous Recombination Deficiency Interventions: MOMA-313, Olaparib Lead Sponsor: MOMA Therapeutics Planned Enrollment: 220 participants

Full Trial Details
View this trial on the source registry
Eligibility criteria, protocol, and results when available
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