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Clinical Trial ● Currently Recruiting Phase I / Phase II NCT07427680

Study of TGM-312-SC01 in Healthy Participants and Adults With MASH

Study of TGM-312-SC01 in Healthy Participants and Adults With MASH — Recruiting • Phase I / Phase II • Diabetes / Metabolic • NCT07427680.

📅 27 Mar 2026 ⏱ 1 min read
Currently Recruiting
This trial is actively seeking participants in the UK. Discuss eligibility with your patient before referring.
Status
Currently Recruiting
Phase
Phase I / Phase II
NCT ID
NCT07427680
Start
2026-02
Completion
2028-03
ClinicaliQ Trial Snapshot
  • Study of TGM-312-SC01 in Healthy Participants and Adults With MASH — Recruiting • Phase I / Phase II • Diabetes / Metabolic • NCT07427680.
  • Review the linked registry entry for study design, population, endpoints, and operational status.

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What This Trial Is Studying

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) effects of single ascending doses of TGM-312-SC01 in healthy adults and multiple ascending doses in patients with metabolic dysfunction-associated steatohepatitis (MASH). Conditions: Healthy Participants, MASH - Metabolic Dysfunction-Associated Steatohepatitis Interventions: TGM-312-SC01, Placebo Lead Sponsor: Tangram Therapeutics Plc Planned Enrollment: 99 participants

Full Trial Details
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Eligibility criteria, protocol, and results when available
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