- Study of TGM-312-SC01 in Healthy Participants and Adults With MASH — Recruiting • Phase I / Phase II • Diabetes / Metabolic • NCT07427680.
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The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) effects of single ascending doses of TGM-312-SC01 in healthy adults and multiple ascending doses in patients with metabolic dysfunction-associated steatohepatitis (MASH). Conditions: Healthy Participants, MASH - Metabolic Dysfunction-Associated Steatohepatitis Interventions: TGM-312-SC01, Placebo Lead Sponsor: Tangram Therapeutics Plc Planned Enrollment: 99 participants