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GLP-1 Agonists: Semaglutide, Tirzepatide and the Cardiovascular Revolution

GLP-1 agonists have transformed the treatment of type 2 diabetes and obesity. In this episode, Dr Anzal Qurbain explains how they work, the landmark cardiovascular trials that changed prescribing practice, the significant weight loss data, and the key safety considerations every prescriber needs to know.

🎓 Dr Anzal Qurbain 📅 3 April 2026 ⏰ 00:15:32
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Public / open access

ClinicaliQ-created or curated content with no sponsor influence.

This on-demand webinar is a recorded episode from the Drug Class Explainers series.
Listen to the full session below and earn 0.5 CPD hours upon completion.

Use the slide outline alongside the recording for a structured review of the session.

GLP-1 agonists — session overview

  • Why GLP-1 biology matters in diabetes and obesity
  • How incretin signalling links gut, pancreas, appetite and metabolism

Physiological GLP-1 signalling

  • GLP-1 release after nutrient intake
  • Glucose-dependent insulin secretion and glucagon suppression
  • Effects on gastric emptying and satiety

Drug-class rationale

  • Why GLP-1 receptor agonists last longer than native GLP-1
  • Practical differences between short-acting and longer-acting approaches
  • Weekly injectable therapy as a clinical workflow consideration

Semaglutide and tirzepatide in context

  • Drug-class positioning within modern metabolic care
  • Diabetes, obesity and cardio-metabolic risk as overlapping clinical problems
  • Importance of balanced discussion and patient selection

Safety and tolerability discussion

  • Gastrointestinal adverse effects and dose escalation
  • Counselling points and follow-up considerations
  • When to review, pause or reassess therapy

Clinical takeaways

  • Match mechanism to patient goals and risk profile
  • Separate educational discussion from product-specific promotion
  • Use current guidance and local formulary pathways when making prescribing decisions
🎓
Dr Anzal Qurbain
Specialist Speaker
00:15:32
0.5 — UK CPD accredited
📅3 April 2026
🎓Dr Anzal Qurbain
🌐Watch on demand, online
Diabetes / Metabolic
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