Gastroenterology
Gastroenterology guidance, inflammatory bowel disease mechanisms, trial updates and education for clinicians following digestive disease evidence.
Latest Guidelines
2022 ESPGHAN Guidelines on Coeliac Disease Diagnosis
This ESPGHAN guideline addresses 2022 ESPGHAN Guidelines on Coeliac Disease Diagnosis in Gastroenterology. Use it to review current recommendation wording, eligibility criteria, and implementation considerations in…
2023 EASL Clinical Practice Guidelines on Cirrhosis
This EASL guideline addresses 2023 EASL Clinical Practice Guidelines on Cirrhosis in Gastroenterology. Use it to review current recommendation wording, eligibility criteria, and implementation considerations in…
2023 EASL-EASD-EASO Clinical Practice Guidelines for MASLD
This EASL guideline addresses 2023 EASL-EASD-EASO Clinical Practice Guidelines for MASLD in Gastroenterology. Use it to review current recommendation wording, eligibility criteria, and implementation considerations in…
2022 EASL Clinical Practice Guidelines on Hepatitis C
This EASL guideline addresses 2022 EASL Clinical Practice Guidelines on Hepatitis C in Gastroenterology. Use it to review current recommendation wording, eligibility criteria, and implementation considerations…
Pancreatitis (NICE NG104)
Confirm acute pancreatitis diagnosis using serum lipase (or amylase if unavailable) with characteristic clinical features; perform baseline assessment including FBC, U&Es, LFTs, glucose, calcium, CRP and…
Acute Upper Gastrointestinal Bleeding in Over 16s (NICE CG141)
Use Glasgow-Blatchford score at initial assessment to stratify risk and determine whether patients can be managed as outpatients or require admission Insert two large-bore IV cannulae…
Trial Radar
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein
Treatment being tested: Fazirsiran, an investigational therapy designed to reduce liver fibrosis in patients with alpha-1 antitrypsin (AAT)…
TrialApplication of Functional Renal MRI to Improve Assessment of Chronic Kidney Disease
MRI scan measures kidney structure and function to predict chronic kidney disease progression and guide treatment decisions.
PHASE2, PHASE3A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn’s Disease
Guselkumab, a new antibody treatment, shows promise for reducing symptoms and inflammation in moderate-to-severe Crohn's disease.
TrialRETHINK REFLUX Registry
Long-term safety study tracking patients with surgically implanted LINX reflux devices for up to 10 years after implantation.
Clinical News
‘We have to respond to women’s health needs more easily’
Women's Health Initiative - Key Takeaways Liverpool-based groups are addressing long-standing gaps in women's healthcare provision, highlighting systemic…
24 Apr 2026‘I used delivery apps to hide the shame of alcoholism’
Alcohol addiction can be masked through anonymous delivery services, making problematic drinking less visible to family, friends, and…
09 Apr 2026Incontinence problems leave me ‘leaking while competing’
Childbirth can cause pelvic floor dysfunction severe enough to require surgical intervention, with stress urinary incontinence potentially affecting…
02 Apr 2026Prince William praises £20m milestone for Bowelbabe fund
The Bowelbabe fund, established by Dame Deborah James in 2022, has reached a £20 million fundraising milestone to…
Relevant Mechanisms
Alpha-4-Beta-7 Integrin — Gut-selective Lymphocyte Trafficking
Alpha-4-Beta-7 Integrin — Gut-selective Lymphocyte Trafficking is a clinically relevant Drug Science explainer. Lymphocyte trafficking to the intestinal mucosa is…
MechanismCFTR Modulation
CFTR Modulation is a clinically relevant Drug Science explainer. Cystic fibrosis (CF) is caused by mutations in the CFTR gene…
MechanismJAK-STAT Pathway
JAK-STAT Pathway is a clinically relevant Drug Science explainer. The Janus kinase–signal transducer and activator of transcription (JAK-STAT) pathway is…
MechanismS1P Receptor Modulation — MS/IBD
S1P Receptor Modulation — MS/IBD is a clinically relevant Drug Science explainer. Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite generated…
MechanismThe IL-17/IL-23 Axis
The IL-17/IL-23 Axis is a clinically relevant Drug Science explainer. The IL-23/IL-17 axis is a central driver of immune-mediated inflammatory…
CPD, Podcasts & Webinars
No specialty-tagged education live yet
Gastroenterology podcasts, webinars and CPD modules will appear here as new education is published and tagged.
Useful starting points in Gastroenterology
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein
Treatment being tested: Fazirsiran, an investigational therapy designed to reduce liver fibrosis in patients with alpha-1 antitrypsin (AAT)…
TrialApplication of Functional Renal MRI to Improve Assessment of Chronic Kidney Disease
MRI scan measures kidney structure and function to predict chronic kidney disease progression and guide treatment decisions.
Clinical News‘We have to respond to women’s health needs more easily’
Women's Health Initiative - Key Takeaways Liverpool-based groups are addressing long-standing gaps in women's healthcare provision, highlighting systemic…
Education that still supports this area
SGLT2 Inhibitors: From Glycaemia to Heart Failure and Chronic Kidney Disease
recorded webinar focused on SGLT2 Inhibitors in diabetes and metabolic medicine. Use the recording with the slide outline…
WebinarJAK Inhibitors: Updated Safety Signals, Patient Selection and Post-ORAL Surveillance
Recorded webinar focused on JAK inhibitors in rheumatology and immune-mediated inflammatory disease. Reviews JAK-STAT signalling, patient selection, ORAL…
WebinarGLP-1 Agonists: Semaglutide, Tirzepatide and the Cardiovascular Revolution
recorded webinar focused on GLP-1 Agonists in diabetes and metabolic medicine. Use the recording with the slide outline…
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