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MHRA • NHS England • NICE • UKHSA

Clinical News & Alerts

1103+ sourced updates — safety alerts, regulatory decisions and NHS England announcements, verified for UK clinicians.

MHRA Safety Alert NHS England NICE Update UKHSA
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Clinical News

Latest Alerts & Updates

⚠️ Safety Alert
MHRA Gastroenterology
Fezolinetant▼(Veoza): risk of liver injury; new recommendations to minimise risk
Fezolinetant treatment is associated with a risk of drug induced liver injury. New recommendations have been introduced to minimise this risk. Liver…
10 Apr 2025 View brief →
⚠️ Safety Alert
MHRA
Prolonged-release opioids: Removal of indication for relief of post-operative pain
Prolonged-release opioids: Removal of indication for relief of post-operative pa...
12 Mar 2025 View brief →
⚠️ Safety Alert
MHRA
Letters and medicine recalls sent to healthcare professionals in January 2025
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.  This update is best treated as…
26 Feb 2025 View brief →
⚠️ Safety Alert
MHRA
Valproate (Belvo, Convulex, Depakote, Dyzantil, Epilim, Epilim Chrono or Chronosphere, Episenta, Epival, and Syonell▼): review by two specialists is required for initiating valproate but not for male patients already taking valproate
Valproate (Belvo, Convulex, Depakote, Dyzantil, Epilim, Epilim Chrono or Chrono...
13 Feb 2025 View brief →
⚠️ Safety Alert
MHRA Diabetes / Metabolic
GLP-1 and dual GIP/GLP-1 receptor agonists: potential risk of pulmonary aspiration during general anaesthesia or deep sedation
Healthcare professionals should be aware of the potential risk of pulmonary aspiration in patients using GLP-1 or dual GIP/GLP-1 receptor agonists who…
28 Jan 2025 View brief →
⚠️ Safety Alert
MHRA
Letters and medicine recalls sent to healthcare professionals in December 2024
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices.  This update is best treated as…
28 Jan 2025 View brief →
⚠️ Safety Alert
MHRA
Letters and medicine recalls sent to healthcare professionals in November 2024
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. This update is best treated as…
12 Dec 2024 View brief →
⚠️ Safety Alert
MHRA
MedSafetyWeek November 2024: your Yellow Card report helps prevent future harm to others and improves patient safety
The ninth annual #MedSafetyWeek social media campaign is taking place 4 to 10 November 2024. This update is best treated as a…
06 Nov 2024 View brief →
⚠️ Safety Alert
MHRA
Letters and medicine recalls sent to healthcare professionals in October 2024
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. This update is best treated as…
06 Nov 2024 View brief →
⚠️ Safety Alert
MHRA Diabetes / Metabolic
GLP-1 receptor agonists: reminder of the potential side effects and to be aware of the potential for misuse
Healthcare professionals are reminded to inform patients about the common and serious side effects associated with glucagon-like peptide-1 receptor agonists (GLP-1RAs). This…
24 Oct 2024 View brief →