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MHRA • NHS England • NICE • UKHSA

Clinical News & Alerts

1103+ sourced updates — safety alerts, regulatory decisions and NHS England announcements, verified for UK clinicians.

MHRA Safety Alert NHS England NICE Update UKHSA
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Clinical News

Latest Alerts & Updates

⚠️ Safety Alert
MHRA Diabetes / Metabolic
Insulin pumps and continuous glucose monitoring (CGM) equipment: guidance for users on reporting suspected adverse incidents and safety concerns to the MHRA’s Yellow Card scheme
We ask healthcare professionals to support new guidance for users of diabetes management equipment, their families, care givers and representatives. This update…
24 Oct 2024 View brief →
⚠️ Safety Alert
MHRA Cardiology / Cardiovascular
Bromocriptine: monitor blood pressure when prescribing bromocriptine for prevention or inhibition of post-partum physiological lactation
A safety review has been conducted by the MHRA following a Yellow Card report concerning a patient who was taking bromocriptine. The…
24 Oct 2024 View brief →
⚠️ Safety Alert
MHRA
Letters and medicine recalls sent to healthcare professionals in September 2024
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. This update is best treated as…
24 Oct 2024 View brief →
⚠️ Safety Alert
MHRA
Letters and medicine recalls sent to healthcare professionals in August 2024
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. This update is best treated as…
26 Sep 2024 View brief →
⚠️ Safety Alert
MHRA
Valproate use in men: as a precaution, men and their partners should use effective contraception
A retrospective observational study has indicated a possible association between valproate use by men around the time of conception and an increased…
05 Sep 2024 View brief →
⚠️ Safety Alert
MHRA
Yellow Card Biobank: call to contribute to study of genetic links to side effects
Support this initiative to explore whether there is a genetic basis of side effects associated with direct-acting oral anticoagulants (DOACs) and allopurinol.…
21 Aug 2024 View brief →
⚠️ Safety Alert
MHRA
Letters and medicine recalls sent to healthcare professionals in July 2024
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. This update is best treated as…
21 Aug 2024 View brief →
⚠️ Safety Alert
MHRA
Epimax Ointment and Epimax Paraffin-Free Ointment: reports of ocular surface toxicity and ocular chemical injury
Epimax Ointment and Epimax Paraffin-Free Ointment can harm the eyes if used on the face. Do not prescribe these ointments for use…
23 Jul 2024 View brief →
⚠️ Safety Alert
MHRA
Letters and medicine recalls sent to healthcare professionals in June 2024
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. This update is best treated as…
23 Jul 2024 View brief →
⚠️ Safety Alert
MHRA Women's Health
Topiramate (Topamax): introduction of new safety measures, including a Pregnancy Prevention Programme
Topiramate is now contraindicated in pregnancy and in women of childbearing potential unless the conditions of a Pregnancy Prevention Programme are fulfilled.…
20 Jun 2024 View brief →