Drug safety updates, recalls and regulatory warnings from MHRA, organised for rapid clinical review and specialty follow-up.
Amiodarone carries serious risks of pulmonary, hepatic, and thyroid toxicity requiring regular patient monitoring and supervision throughout treatment Healthcare professionals must ensure appropriate baseline investigations and regular follow-up assessments to detect potentially life-threatening adverse…
20 May 2026 · Read clinical summarySupport this initiative to explore whether there is a genetic basis of side effects associated with direct-acting oral anticoagulants (DOACs) and allopurinol. This update is best treated as…
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. This update is best treated as a linked clinical news item for…
Epimax Ointment and Epimax Paraffin-Free Ointment can harm the eyes if used on the face. Do not prescribe these ointments for use on the face. Tell patients to…
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. This update is best treated as a linked clinical news item for…
Topiramate is now contraindicated in pregnancy and in women of childbearing potential unless the conditions of a Pregnancy Prevention Programme are fulfilled. This follows a review by the…
Taking warfarin and tramadol together can cause harmful drug interactions, which can raise the International Normalised Ratio (INR), and result in severe bruising and bleeding, which in some…
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. This update is best treated as a linked clinical news item for…
Topical steroid products are safe and highly effective treatments for the management of a wide range of inflammatory skin diseases but have important risks, especially with prolonged use…
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices, and information about the publication of two recent Device Safety Information pages.…
Finasteride: reminder of the risk psychiatric side effects and of sexual side ef...
Healthcare professionals prescribing montelukast should be alert to the risk of neuropsychiatric reactions in all patients including children and adolescents. Reported neuropsychiatric reactions include sleep disorders, hall… This…
A summary of recent letters and notifications sent to healthcare professionals about medicines and medical devices. This update is best treated as a linked clinical news item for…