Clinical Trials Archive - Page 3 of 16

recruiting PHASE3 Cardiology / Cardiovascular NCT05712200

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

A study to evaluate the effect of abelacimab relative to placebo on the rate of ischemic stroke or systemic embolism (SE) in patients with Atrial Fibrillation (AF) who have been…

Sponsor: Anthos Therapeutics, Inc.

View Trial ClinicalTrials.gov ↗

recruiting Cardiology / Cardiovascular NCT06808217

A Registry on the FARAVIEW Technology of the OPAL HDx Mapping System When Used With the FARAWAVE NAV Ablation Catheter in the Treatment of Atrial Fibrillation

The study is designed to collect data on the acute and long-term (1 year) safety and effectiveness outcome when an ablation procedure is performed in a commercial and standard of…

Sponsor: Boston Scientific Corporation

View Trial ClinicalTrials.gov ↗

recruiting Cardiology / Cardiovascular NCT06905405

The Use of Advanced Imaging in HFpEF

Heart failure with preserved ejection fraction (HFpEF) causes symptoms of breathlessness and leg swelling. It is associated with significant number of hospital admissions and could lead to the patient's death.…

Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust

View Trial ClinicalTrials.gov ↗

recruiting PHASE3 Cardiology / Cardiovascular NCT06424288

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

This study is open to adults aged 18 or above legal age with heart failure. People can join the study if they have heart failure symptoms and a left ventricular…

Sponsor: Boehringer Ingelheim

View Trial ClinicalTrials.gov ↗

recruiting NA Cardiology / Cardiovascular NCT03854071

Development of Novel Physiological CMR Methods in Health and Disease

Physiological cardiovascular stress test plays a crucial role in the assessment of patients with suspected heart disease. There are several methods of cardiac physiological stress tests and each of them…

Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust

View Trial ClinicalTrials.gov ↗

recruiting PHASE2 Cardiology / Cardiovascular NCT06991257

A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)

The purpose of this study is to learn about the safety and effects of the study medicine (PF-07328948) for the possible treatment of heart failure (HF).

Sponsor: Pfizer

View Trial ClinicalTrials.gov ↗

recruiting PHASE2 Cardiology / Cardiovascular NCT05714085

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

This study aims to compare the efficacy of vericiguat versus placebo on change in n-terminal pro-brain natriuretic peptide (NTproBNP) from baseline to Week 16 of the Base Period. The primary…

Sponsor: Merck Sharp & Dohme LLC

View Trial ClinicalTrials.gov ↗

recruiting PHASE3 Cardiology / Cardiovascular NCT07207811

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

This study will find out if a new medicine called NNC6019-0001 can help reduce the risk of heart-related death and illness in participants with a condition called transthyretin amyloid cardiomyopathy…

Sponsor: Novo Nordisk A/S

View Trial ClinicalTrials.gov ↗

recruiting PHASE3 Cardiology / Cardiovascular NCT06307652

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

This is a Phase III, international, multi-centre, randomised, double-blind, parallel-group, double-dummy, active-controlled, event-driven study in patients with chronic HF and impaired kidney function who had a recent HF event. The…

Sponsor: AstraZeneca

View Trial ClinicalTrials.gov ↗

recruiting PHASE3 Cardiology / Cardiovascular NCT06935370

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

This study is open to adults with chronic heart failure (HF) who have a reduced left ventricular ejection fraction (LVEF) of less than 40%. People can join the study if…

Sponsor: Boehringer Ingelheim

View Trial ClinicalTrials.gov ↗

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