Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Neurology Diabetes / Metabolic Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2236 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2236 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

active not recruiting Neurology
Electrical Impedance Tomography of Epilepsy
One-sentence summary: Study testing if EIT brain imaging produces accurate, reproducible results in epilepsy patients compared to MRI, CT, and EEG.
03 Jun 2026 NCT03050931
● Recruiting Phase III Neurology
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
XEN1101 added to existing treatment reduced seizures in patients with primary generalized tonic-clonic seizures compared to placebo.
03 Jun 2026 NCT05667142
active not recruiting Phase III Oncology
A Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously Untreated Metastatic or Unresectable Melanoma
Subcutaneous injection of two cancer drugs works as well as intravenous infusion for untreated advanced melanoma.
03 Jun 2026 NCT05625399
● Recruiting Phase III
A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ – ColdU and SD)
Barzolvolimab reduces symptoms of cold-induced urticaria and dermographism better than placebo in patients uncontrolled on antihistamines.
03 Jun 2026 NCT07266402
active not recruiting Phase III Rheumatology
Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)
Monthly ianalumab injections added to standard lupus treatment reduced disease activity better than placebo.
03 Jun 2026 NCT05624749
● Recruiting Phase III Diabetes / Metabolic
A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities
Orforglipron, a daily weight-loss pill, is being tested in teenagers with obesity or overweight with health complications over 18 months.
03 Jun 2026 NCT06672939
● Recruiting Phase I Oncology
TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
What is being tested: Tulmimetostat (a novel STAT3 inhibitor) combined with either darolutamide or abiraterone, compared to darolutamide monotherapy, to assess safety, tolerability, and…
03 Jun 2026 NCT07190300
● Recruiting Phase II
A Study of the Safety and Activity of Sparsentan for the Treatment of Patients With Immunoglobulin A Nephropathy
What is being tested: Sparsentan, a dual endothelin and angiotensin II receptor antagonist, is being evaluated for its nephroprotective efficacy and safety in patients…
03 Jun 2026 NCT04663204
● Recruiting Phase II Rheumatology
A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH – SLE/LN)
What is being tested: Rapcabtagene autoleucel, a one-time CAR-T cell therapy administered after lymphodepletion, in patients with active, treatment-refractory systemic lupus erythematosus or lupus…
03 Jun 2026 NCT06581198
● Recruiting Phase II Cardiology / Cardiovascular
A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis
What is being tested: LTI-03, an inhaled experimental medication designed to treat Idiopathic Pulmonary Fibrosis (IPF) by addressing the underlying pathophysiology of progressive lung…
03 Jun 2026 NCT06968845
● Recruiting Phase III Cardiology / Cardiovascular
A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide
What is being tested: Two novel bispecific antibody combinations (talquetamab plus pomalidomide, and talquetamab plus teclistamab) are being compared against standard treatment regimens (EPd…
03 Jun 2026 NCT06208150
● Recruiting Cardiology / Cardiovascular
Developing a Brief Intervention to Communicate Cardiovascular Risk to Patients Presenting to the Emergency Department With Chest Pain: a Co-Production Approach. Phase 2.
What is being tested: A brief intervention designed to communicate future cardiovascular risk to emergency department patients with chest pain who have not had…
03 Jun 2026 NCT06903442
● Recruiting Cardiology / Cardiovascular
A Study Investigating the Effectiveness and Safety of Garadacimab for Treating Patients With Hereditary Angioedema (HAE)
Treatment being tested: Garadacimab effectiveness and safety in real-world clinical practice for hereditary angioedema (HAE) management, with long-term follow-up data collected over 48 months…
03 Jun 2026 NCT07001280
● Recruiting Phase III Oncology
A Study to Evaluate Glofitamab as a Single Agent vs. Investigator’s Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma
What is being tested: Glofitamab monotherapy (a CD20/CD3 bispecific antibody) is being compared against standard salvage regimens (rituximab-bendamustine or rituximab-lenalidomide) in patients with relapsed…
03 Jun 2026 NCT06084936
● Recruiting Phase I Oncology
Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors
What is being tested: AZD5335, an antibody-drug conjugate, is being evaluated both as a standalone treatment and combined with established anti-cancer agents to assess…
03 Jun 2026 NCT05797168
● Recruiting Oncology
Vaginal Fluid Derived Biomarkers in the Early Detection and Evolution of Gynaecological Cancers
What is being tested: Vaginal fluid biomarkers are being investigated as potential early detection tools for gynaecological cancers by comparing specific molecular markers in…
03 Jun 2026 NCT07622953
active not recruiting Phase III Gastroenterology
A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)
A drug called resmetirom tested to see if it prevents liver disease progression in patients with advanced fatty liver cirrhosis.
02 Jun 2026 NCT05500222
active not recruiting Cardiology / Cardiovascular
Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation
Comatose cardiac arrest survivors randomly assigned to different sedation depths, body temperatures, and blood pressure targets to find optimal treatment combinations.
02 Jun 2026 NCT05564754
● Recruiting Gastroenterology
The Effects of Postbiotic Supplementation in Female Athletes
Postbiotic supplement versus placebo in active women to assess whether it reduces gut and stomach symptoms during menstrual cycles and exercise.
02 Jun 2026 NCT07580118
active not recruiting Phase I / Phase II Dermatology
Safety and Efficacy Trial of Epcoritamab Combinations in Subjects With B-cell Non-Hodgkin Lymphoma (B-NHL)
Trial testing epcoritamab alone or combined with other drugs for B-cell non-Hodgkin lymphoma across ten treatment arms.
02 Jun 2026 NCT04663347
● Recruiting Phase III
A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich’s Ataxia
Study testing omaveloxolone safety and effectiveness in children aged 2-15 with Friedreich's ataxia over three years.
02 Jun 2026 NCT06953583
active not recruiting Phase III Oncology
A Study of DB-1303/BNT323 vs Investigator’s Choice Chemotherapy in HER2-Low, Hormone Receptor Positive Metastatic Breast Cancer (DYNASTY-Breast02)
DB-1303/BNT323 versus standard chemotherapy for HER2-low, hormone receptor positive advanced breast cancer, measuring time to disease progression.
02 Jun 2026 NCT06018337
● Recruiting Phase II Oncology
Safety and Efficacy of T-DXd vs. CDK4/6i-based ET as First-line Therapy of HR-positive and HER2-low/Ultralow Advanced Breast Cancer Patients Classified as Non-luminal Subtype
What is being tested: Trastuzumab deruxtecan (T-DXd), an antibody-drug conjugate, is being compared against standard CDK4/6 inhibitor-based endocrine therapy as first-line treatment for HR-positive/HER2-low…
02 Jun 2026 NCT06486883
● Recruiting Phase I
Study of BHV-1400 in IgA Nephropathy
What is being tested: BHV-1400, a novel investigational treatment, is being evaluated for safety and tolerability in patients with IgA Nephropathy (IgAN), the most…
02 Jun 2026 NCT07054684
● Recruiting Phase I Cardiology / Cardiovascular
A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)
Being Tested: Surzetoclax, an oral agent, administered alone or combined with established subcutaneous/oral antimyeloma treatments, to evaluate safety profile and disease activity changes in…
02 Jun 2026 NCT06953960
● Recruiting Cardiology / Cardiovascular
Heart Failure Carer Support Programme: Implementation Testing in the UK.
What is being tested: An implementation programme designed to provide structured support and preparation for family carers of heart failure patients, addressing the gap…
02 Jun 2026 NCT07373041
● Recruiting Phase III Oncology
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician’s Choice in Subjects With Relapsed Small Cell Lung Cancer
What is being tested: Ifinatamab deruxtecan (I-DXd), a novel antibody-drug conjugate targeting DLL3, is being compared against standard physician-selected chemotherapy in patients with relapsed…
02 Jun 2026 NCT06203210
● Recruiting Phase I Oncology
Pharmacokinetics and Safety Study of Pelabresib in Patients With Advanced Malignancies and Hepatic Impairment
What is being tested: Pelabresib pharmacokinetics and safety in patients with advanced malignancies, specifically comparing drug exposure and clearance between those with hepatic impairment…
02 Jun 2026 NCT07422610
● Recruiting Phase III Oncology
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma
What is being tested: A triple combination therapy consisting of subcutaneous epcoritamab (bispecific antibody), intravenous rituximab (monoclonal antibody), and oral lenalidomide (immunomodulatory agent) in…
02 Jun 2026 NCT06191744
● Recruiting Phase II
Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders
Tafasitamab was tested in adults with autoimmune blood disorders to assess whether it was safe and effective.
01 Jun 2026 NCT07104565
active not recruiting Phase III
A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy
Trial testing a new add-on treatment (taldefgrobep alfa) alongside existing spinal muscular atrophy medicines to see if it helps and is safe.
01 Jun 2026 NCT05337553
active not recruiting Diabetes / Metabolic
EasiVits Acceptability & Tolerance Study
EasiVits trial tested new low-carbohydrate, unflavoured vitamin supplements designed to improve adherence in children with metabolic disorders requiring restricted diets.
01 Jun 2026 NCT07619170
active not recruiting Phase III Oncology
A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma.
Adding tazemetostat to lenalidomide and rituximab improves progression-free survival in relapsed/refractory follicular lymphoma compared to placebo.
01 Jun 2026 NCT04224493
active not recruiting Phase II
A Study of Acalabrutinib Plus Venetoclax and Rituximab in Participants With Treatment Naïve Mantle Cell Lymphoma
TrAVeRse Trial Summary Acalabrutinib, venetoclax and rituximab combination therapy for untreated mantle cell lymphoma, testing whether maintenance treatment improves outcomes.
01 Jun 2026 NCT05951959
● Recruiting Dermatology
Characterization And Clinical Outcomes of AA Patients Treated With Ritlecitinib
Ritlecitinib (JAK3 inhibitor) shows effective hair regrowth in severe alopecia areata patients in routine clinical practice.
01 Jun 2026 NCT06531109
● Recruiting Phase III Oncology
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
Treatment being tested: BNT327 (pumitamig), a novel investigational therapy, combined with standard chemotherapy (etoposide/carboplatin) versus the current standard of care atezolizumab plus chemotherapy in…
01 Jun 2026 NCT06712355
● Recruiting
Diagnostic and Therapeutic Applications in Microarrays in Organ Transplantation
What is being tested: Microarray-based molecular diagnostic approaches to replace or supplement the current Banff Classification consensus system for identifying kidney transplant dysfunction, using…
01 Jun 2026 NCT01299168
● Recruiting Rheumatology
A Prospective Randomised Study of Treatment Selection Based on Epigenetic Markers Versus Standard of Care Treatment Selection in Adults With CROHN’s Disease
What is being tested: Epigenome-guided treatment selection for biologic therapy in active Crohn's disease, comparing personalised epigenetic marker-based approaches against standard-of-care treatment protocols to…
01 Jun 2026 NCT07363044
● Recruiting Phase II Respiratory / COPD / Asthma
Study to Evaluate the Efficacy, Safety, and Tolerability of PIPE 791 in Subjects With Idiopathic Pulmonary Fibrosis
What is being tested: PIPE-791, a novel investigational agent, is being evaluated in a Phase 2 randomised controlled trial to assess its efficacy, safety,…
01 Jun 2026 NCT07284459
● Recruiting Oncology
Strategy for EArly Recognition of Cancer, COPD & Heart Failure in the Emergency Department
What is being tested: A computer programme designed to assist emergency department clinicians in earlier recognition and diagnosis of three major conditions—cancer, COPD, and…
01 Jun 2026 NCT07391280
● Recruiting Phase I Oncology
A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
What is being tested: Pembrolizumab (an anti-PD-1 immunotherapy checkpoint inhibitor) is being evaluated for efficacy and safety in pediatric patients with advanced solid tumors,…
01 Jun 2026 NCT02332668
● Recruiting Phase III Oncology
A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis
Treatment being tested: Remibrutinib, a Bruton's tyrosine kinase (BTK) inhibitor, is being evaluated as an add-on therapy to standard-of-care treatment in generalised myasthenia gravis…
01 Jun 2026 NCT06744920
● Recruiting Phase I / Phase II
A Study of AAVB-039 in Participants With Stargardt Disease (STGD1)
Gene therapy injection for Stargardt disease shows safety and early effectiveness in patients with ABCA4 gene mutations.
29 May 2026 NCT07161544
● Recruiting
PRESERFLO™ MicroShunt XI Observational PMCF Study With no Control Group
This study tracks safety and effectiveness of a tiny glaucoma drainage device in patients whose eye pressure remains too high despite maximum medication.
29 May 2026 NCT07235592
active not recruiting Phase III Dermatology
Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to <18 Years of Age With Atopic Dermatitis (AD)
Long-term safety and effectiveness study of dupilumab injection in children aged six months to eighteen years with atopic dermatitis.
29 May 2026 NCT02612454
active not recruiting Phase I / Phase II Oncology
A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin’s Lymphoma
Early-stage trial testing new cancer drug englumafusp alfa combined with existing treatments in patients with relapsed/refractory lymphoma.
29 May 2026 NCT04077723
active not recruiting Phase III Neurology
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)
Remibrutinib and teriflunomide showed similar effectiveness and safety for treating relapsing multiple sclerosis.
29 May 2026 NCT05156281
active not recruiting Phase III Neurology
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)
Remibrutinib was tested against teriflunomide in relapsing MS patients to compare how well each drug works and its safety profile.
29 May 2026 NCT05147220
active not recruiting
Stryker PEEK Customized Implant: A Prospective Post Market Follow Up to Evaluate Safety, Performance and Effectiveness
Custom PEEK implants safely restore bone and soft tissue defects in the skull and face over two years.
29 May 2026 NCT05362370
● Recruiting Phase II Rheumatology
A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
Trial testing whether new drug BI 3000202 at different doses improves lupus symptoms in adults over one year.
29 May 2026 NCT07409181