Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
Explore Trial Collections Follow research updates
All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
🔬
Trial Radar

Clinical Trial Intelligence

● Recruiting Phase III Cardiology / Cardiovascular
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
Drug being tested: Mavorixafor, a CXCR4 antagonist, is being evaluated for efficacy, safety and tolerability in patients with chronic neutropenic disorders (both congenital and…
14 Apr 2026 NCT06056297
● Recruiting Phase III Oncology
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
What is being tested: Amivantamab (a bispecific antibody) combined with standard chemotherapy (mFOLFOX6 or FOLFIRI) versus the current standard treatment of cetuximab plus chemotherapy…
14 Apr 2026 NCT06662786
● Recruiting Phase III Oncology
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
What is being tested: Amivantamab (a bispecific antibody targeting EGFR and MET) combined with FOLFIRI chemotherapy, compared to the standard treatment of cetuximab/bevacizumab with…
14 Apr 2026 NCT06750094
● Recruiting Phase III Oncology
A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
Treatment being tested: Pasritamig (a novel therapeutic agent) combined with docetaxel chemotherapy versus docetaxel alone in metastatic castration-resistant prostate cancer (mCRPC), with primary endpoint…
14 Apr 2026 NCT07225946
● Recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
What is being tested: Divarasib (a KRAS G12C inhibitor) combined with pembrolizumab (immunotherapy) versus standard chemotherapy (pemetrexed plus carboplatin or cisplatin) combined with pembrolizumab…
14 Apr 2026 NCT06793215
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
What is being tested: Finerenone (a non-steroidal mineralocorticoid receptor antagonist) safety and tolerability in children and young adults aged 1-18 years with chronic kidney…
14 Apr 2026 NCT05457283
● Recruiting Phase III
A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression
What is being tested: Sefaxersen (RO7434656), a novel antisense oligonucleotide therapy designed to reduce kidney disease progression in patients with primary IgA nephropathy who…
14 Apr 2026 NCT05797610
● Recruiting Phase III
Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN
What is being tested: Long-term efficacy, safety and tolerability of iptacopan, a Factor B inhibitor targeting the alternative complement pathway, in patients with C3…
14 Apr 2026 NCT03955445
● Recruiting Phase III Rheumatology
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
Treatment being tested: Long-term safety and efficacy of guselkumab (an IL-23 inhibitor administered subcutaneously) in pediatric patients with moderately to severely active ulcerative colitis,…
14 Apr 2026 NCT06663332
● Recruiting Phase III Rheumatology
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
What is being tested: Oral icotrokinra, a novel therapeutic agent, is being evaluated for its efficacy, safety, and tolerability in treating moderately to severely…
14 Apr 2026 NCT07196748
● Recruiting Phase III Cardiology / Cardiovascular
A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE
What is being tested: Milvexian, a Factor XIa inhibitor, is being evaluated as a novel anticoagulant to reduce recurrent ischemic stroke risk compared to…
14 Apr 2026 NCT05702034
● Recruiting Phase III Cardiology / Cardiovascular
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Intervention being tested: Treprostinil palmitil inhalation powder (TPIP) administered once daily for 24 weeks as a potential treatment for pulmonary hypertension associated with interstitial…
14 Apr 2026 NCT07179380
● Recruiting Phase III Oncology
A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)
What is being tested: BMS-986393 (arlo-cel), a novel therapeutic agent, is being compared against standard treatment regimens in patients with relapsed or refractory multiple…
14 Apr 2026 NCT06615479
● Recruiting Phase III Oncology
ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors
What is being tested: ONC-392 (gotistobart), a next-generation anti-CTLA-4 antibody, is being compared against standard docetaxel chemotherapy in patients with metastatic non-small cell lung…
14 Apr 2026 NCT05671510
● Recruiting Phase III Oncology
Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer
What is being tested: Saruparib (a PARP inhibitor) combined with camizestrant (an estrogen receptor degrader) versus standard CDK4/6 inhibitor plus endocrine therapy in patients…
14 Apr 2026 NCT06380751
active not recruiting Phase III
A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma
CAR-T cell therapy cilta-cel compared with standard chemotherapy in patients with relapsed multiple myeloma resistant to lenalidomide.
13 Apr 2026 NCT04181827
● Recruiting Phase III
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
Trial testing whether adding bleximenib to venetoclax-azacitidine improves outcomes in newly diagnosed AML with specific genetic mutations.
13 Apr 2026 NCT06852222
active not recruiting Phase III Oncology
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Participants With Metastatic Prostate Cancer
Adding niraparib to standard prostate cancer treatment (abiraterone and prednisone) delays cancer progression compared to standard treatment alone.
13 Apr 2026 NCT03748641
● Recruiting Phase II / Phase III
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).
Aficamten improves symptoms and safety in children with obstructive hypertrophic cardiomyopathy, a serious heart muscle condition.
13 Apr 2026 NCT06412666
● Recruiting Phase III Oncology
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma
Trial testing new drug epcoritamab combined with existing treatments for untreated follicular lymphoma, measuring safety and effectiveness in 1095 patients.
13 Apr 2026 NCT06191744
● Recruiting Phase III Infectious Disease
BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies
Trial testing a group B streptococcus vaccine in pregnant women and babies to assess safety and immune response.
13 Apr 2026 NCT07160244
● Recruiting Phase III Oncology
A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy
New hormone therapy drug tested against standard treatment in early breast cancer patients who've completed two years of initial hormone therapy.
13 Apr 2026 NCT05774951
active not recruiting Phase III Oncology
A Study of TAR-200 Versus Intravesical Chemotherapy in Participants With Recurrent High-Risk Non-Muscle-Invasive Bladder Cancer (HR-NMIBC) After Bacillus Calmette-Guérin (BCG)
TAR-200 compared to standard chemotherapy for bladder cancer recurrence after BCG in patients refusing surgery.
13 Apr 2026 NCT06211764
● Recruiting Phase III Respiratory / COPD / Asthma
Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
What is being tested: Depemokimab, a biologic therapy administered as an add-on treatment, is being evaluated for efficacy and safety in patients with uncontrolled…
10 Apr 2026 NCT06961214
● Recruiting Phase III Cardiology / Cardiovascular
A Study of Navenibart in Participants With Hereditary Angioedema
What is being tested: Navenibart, a subcutaneous treatment for hereditary angioedema (HAE types 1 and 2), is being evaluated in a Phase 3 randomised…
10 Apr 2026 NCT06842823
● Recruiting Phase III Oncology
A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)
What is being tested: Safety and risk of tumor lysis syndrome (TLS) in treatment-naïve adults with CLL receiving venetoclax combined with either intravenous obinutuzumab…
10 Apr 2026 NCT06428019
● Recruiting Phase III Oncology
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
What is being tested: Rilvegostomig (a novel VEGF inhibitor) combined with fluoropyrimidine chemotherapy and trastuzumab deruxtecan (T-DXd) versus standard trastuzumab plus chemotherapy with pembrolizumab…
10 Apr 2026 NCT06764875
● Recruiting Phase III Oncology
A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma
What is being tested: Ficlatuzumab (a hepatocyte growth factor inhibitor) combined with cetuximab versus placebo plus cetuximab in patients with recurrent or metastatic HPV-negative…
10 Apr 2026 NCT06064877
active not recruiting Phase III
Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis
Trial testing selinexor combined with ruxolitinib versus ruxolitinib alone for untreated myelofibrosis patients.
09 Apr 2026 NCT04562389
active not recruiting Phase III Oncology
Effectiveness Study of Nivolumab Compared to Placebo in Prevention of Recurrent Melanoma After Complete Resection of Stage IIB/C Melanoma
Nivolumab immunotherapy reduced melanoma recurrence risk compared to placebo in high-risk patients after surgery.
09 Apr 2026 NCT04099251
active not recruiting Phase III Oncology
Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)
TAILORx showed hormone therapy alone is sufficient for most women with early-stage hormone-responsive breast cancer, avoiding unnecessary chemotherapy.
09 Apr 2026 NCT00310180
● Recruiting Phase III
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Trial testing two new drugs (pozelimab and cemdisiran) to slow vision loss in advanced age-related macular degeneration.
09 Apr 2026 NCT06541704
● Recruiting Phase II / Phase III Neurology
Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
BHV-7000 is being tested to see if it works safely in adults with focal epilepsy that doesn't respond to current drugs.
09 Apr 2026 NCT06309966
● Recruiting Phase III Oncology
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
New drug rilvegostomig combined with chemotherapy and trastuzumab deruxtecan tested against standard immunotherapy treatment for advanced HER2-positive stomach cancer.
09 Apr 2026 NCT06764875
● Recruiting Phase III Oncology
A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma
Trial testing whether adding ficlatuzumab to cetuximab improves survival in advanced HPV-negative head and neck cancer.
09 Apr 2026 NCT06064877
● Recruiting Phase II / Phase III Diabetes / Metabolic
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis
A trial testing clazakizumab (an anti-inflammatory drug) to reduce heart disease and death in dialysis patients with inflammation. Word count: 18 words
09 Apr 2026 NCT05485961
active not recruiting Phase III Oncology
A Study of Subcutaneously Injected Epcoritamab Plus Oral Lenalidomide Tablets Compared to Intravenously (IV) Infused Rituximab Plus IV Infused Gemcitabine and IV Infused Oxaliplatin in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Trial comparing injected epcoritamab plus tablets (with or without lenalidomide) to intravenous chemotherapy for relapsed/refractory lymphoma.
08 Apr 2026 NCT06508658
active not recruiting Phase III Oncology
A Phase 3 Trial of Epcoritamab vs Investigator’s Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)
Epcoritamab (injected weekly then fortnightly) compared to standard chemotherapy for people with relapsed/refractory lymphoma ineligible for stem cell transplant.
08 Apr 2026 NCT04628494
● Recruiting Phase III Cardiology / Cardiovascular
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) is Recruiting • Phase III…
08 Apr 2026 NCT07517263
● Recruiting Phase III Oncology
Beamion LUNG-3: A Study to Test Whether Zongertinib Helps People With Surgically Removed, Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment
Beamion LUNG-3: A Study to Test Whether Zongertinib Helps People With Surgically Removed, Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment…
08 Apr 2026 NCT07195695
● Recruiting Phase III Oncology
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial…
08 Apr 2026 NCT06989112
● Recruiting Phase III Dermatology
A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis
A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than…
07 Apr 2026 NCT06461897
● Recruiting Phase III Diabetes / Metabolic
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight is Recruiting • Phase III…
07 Apr 2026 NCT07339423
● Recruiting Phase III Oncology
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer is Recruiting • Phase III…
07 Apr 2026 NCT05253651
● Recruiting Phase III Oncology
A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC) is Recruiting • Phase III • Oncology • NCT07164443. The…
07 Apr 2026 NCT07164443
● Recruiting Phase III Oncology
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer…
07 Apr 2026 NCT07062965
● Recruiting Phase III Oncology
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation…
07 Apr 2026 NCT05696626
● Recruiting Phase III Cardiology / Cardiovascular
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation is Recruiting • Phase III •…
07 Apr 2026 NCT06200207
● Recruiting Phase III Oncology
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer…
07 Apr 2026 NCT06875310
● Recruiting Phase III Oncology
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell…
07 Apr 2026 NCT06758401