Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase III Oncology
A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)
What is being tested: This Phase 3 trial compares belantamab mafodotin combined with lenalidomide and dexamethasone (BRd) against daratumumab combined with lenalidomide and dexamethasone…
22 Apr 2026 NCT06679101
● Recruiting Phase III Oncology
A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma
What is being tested: Zanubrutinib (a Bruton tyrosine kinase inhibitor) combined with obinutuzumab (anti-CD20 monoclonal antibody) versus the standard regimen of lenalidomide plus rituximab…
22 Apr 2026 NCT05100862
● Recruiting Phase III Oncology
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis
Treatment being tested: IMVT-1402, a novel therapeutic agent, is being evaluated for efficacy, safety and tolerability in adults with generalized myasthenia gravis across mild…
22 Apr 2026 NCT07039916
● Recruiting Phase III Oncology
Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)
What is being tested: A novel oral cladribine formulation is being evaluated against placebo for efficacy and safety in treating generalized myasthenia gravis (gMG),…
22 Apr 2026 NCT06463587
● Recruiting Phase III Oncology
A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR – HN1)
Treatment being tested: Petosemtamab (a fibroblast activation protein inhibitor) combined with pembrolizumab compared to pembrolizumab monotherapy as first-line treatment for recurrent or metastatic head…
22 Apr 2026 NCT06525220
● Recruiting Phase III
A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)
A new drug (claseprubart) tested against placebo in adults with chronic inflammatory demyelinating polyneuropathy to assess whether it works and is safe.
21 Apr 2026 NCT06858579
active not recruiting Phase III
Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis
ALXN1720 (a complement inhibitor) was tested for safety and effectiveness in treating autoimmune myasthenia gravis in adults.
21 Apr 2026 NCT05556096
● Recruiting Phase III
A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)
Anifrolumab injection added to standard treatment improved muscle disease activity in adults with polymyositis and dermatomyositis compared to placebo.
21 Apr 2026 NCT06455449
active not recruiting Phase III Oncology
A Study to Compare ABP 234 and Keytruda® (Pembrolizumab) in Participants With Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer
Trial comparing a biosimilar copy of Keytruda with the original drug in advanced lung cancer patients to confirm equivalent effectiveness.
21 Apr 2026 NCT06311721
active not recruiting Phase III Gastroenterology
A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn’s Disease
Guselkumab (IL-23 inhibitor) tested for treating perianal fistulas in Crohn's disease patients, measuring effectiveness and safety.
21 Apr 2026 NCT05347095
● Recruiting Phase III Oncology
A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation
Treatment being tested: Saruparib (AZD5305), a PARP inhibitor, combined with standard radiotherapy and androgen deprivation therapy versus placebo in men with high-risk and very…
21 Apr 2026 NCT06952803
● Recruiting Phase III Neurology
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer’s Disease (ADEPT-5)
Treatment being tested: KarXT + KarX-EC combination therapy, a novel muscarinic M1/M4 receptor agonist approach, being evaluated specifically for psychosis symptoms in Alzheimer's disease…
21 Apr 2026 NCT06947941
● Recruiting Phase III Respiratory / COPD / Asthma
Randomised Evaluation of COVID-19 Therapy
What is being tested: RECOVERY is evaluating multiple therapeutic interventions (antivirals, immunomodulators, corticosteroids, and other agents) in hospitalised pneumonia patients, with the primary aim…
21 Apr 2026 NCT04381936
● Recruiting Phase III Oncology
AZD0486 1L Therapy for Elderly or Unfit Participants With LBCL
What is being tested: The trial compares R-mini-CHOP chemotherapy (2 cycles) followed by AZD0486 versus standard R-mini-CHOP (6 cycles) as first-line treatment for large…
21 Apr 2026 NCT07215585
● Recruiting Phase III Oncology
SUPRAME-ACTengine® IMA203 vs. Investigator’s Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma
Treatment Being Tested: IMA203, a novel immunotherapy agent, is being compared against investigator's choice of standard treatments (such as checkpoint inhibitors or chemotherapy) in…
21 Apr 2026 NCT06743126
active not recruiting Phase III Cardiology / Cardiovascular
A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) – ACCLAIM-Lp(a)
Lepodisiran injection reduces heart attacks and strokes in patients with high lipoprotein(a) levels and existing heart disease.
20 Apr 2026 NCT06292013
● Recruiting Phase III Oncology
A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).
What is being tested: PF-06821497 (mevrometostat), a novel investigational medicine, combined with enzalutamide versus standard treatments (enzalutamide alone or docetaxel chemotherapy) in men with…
20 Apr 2026 NCT06551324
● Recruiting Phase III Oncology
Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)
What is being tested: Capivasertib (AKT inhibitor) combined with CDK4/6 inhibitors and fulvestrant compared to CDK4/6 inhibitors and fulvestrant alone in advanced/metastatic HR+/HER2- breast…
20 Apr 2026 NCT04862663
● Recruiting Phase III Respiratory / COPD / Asthma
Outpatient Treatment With Anti-Coronavirus Immunoglobulin
What is being tested: A single infusion of anti-COVID-19 hyperimmune intravenous immunoglobulin (hIVIG) compared to placebo in recently diagnosed COVID-19 patients, evaluating both safety…
20 Apr 2026 NCT04910269
● Recruiting Phase III Oncology
DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy
What is being tested: Obrixtamig (a DLL3-targeting agent) combined with atezolizumab, carboplatin, and etoposide versus standard chemotherapy alone in adults with advanced small cell…
20 Apr 2026 NCT07472517
● Recruiting Phase III Oncology
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
What is being tested: Sotorasib (a KRAS G12C inhibitor) combined with platinum doublet chemotherapy versus pembrolizumab (PD-L1 inhibitor) combined with platinum doublet chemotherapy as…
20 Apr 2026 NCT05920356
active not recruiting Phase III Diabetes / Metabolic
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
Weekly semaglutide injections tested against placebo over 5 years to see if it helps fatty liver disease.
17 Apr 2026 NCT04822181
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
What is being tested: Finerenone (a non-steroidal mineralocorticoid receptor antagonist) efficacy, safety, and pharmacokinetics in children with heart failure and left ventricular systolic dysfunction,…
17 Apr 2026 NCT07188805
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria
Treatment being tested: Finerenone (a non-steroidal mineralocorticoid receptor antagonist) in combination with ACE inhibitors or angiotensin receptor blockers in children with chronic kidney disease…
17 Apr 2026 NCT05196035
● Recruiting Phase III Cardiology / Cardiovascular
Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease
What is being tested: Orforglipron, a once-daily treatment, is being evaluated for its efficacy and safety in managing Fontaine II peripheral arterial disease (symptomatic…
17 Apr 2026 NCT07223593
● Recruiting Phase III Cardiology / Cardiovascular
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
What is being tested: AZD0780, an oral PCSK9 inhibitor, is being evaluated in a Phase III randomized controlled trial to assess its efficacy in…
17 Apr 2026 NCT07000357
● Recruiting Phase III Cardiology / Cardiovascular
A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)
What is being tested: Orforglipron (LY3502970), a GLP-1 receptor agonist, is being evaluated for its effects on cardiovascular outcomes compared to placebo over approximately…
17 Apr 2026 NCT07241390
● Recruiting Phase III Oncology
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
Intervention being tested: Vepugratinib (LY3866288), a novel therapeutic agent, is being evaluated against placebo in a randomised controlled trial to assess safety, tolerability, and…
17 Apr 2026 NCT07218380
● Recruiting Phase III Oncology
Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia
A new drug combination tested against standard treatment in older adults with newly diagnosed acute lymphoblastic leukaemia.
16 Apr 2026 NCT04994717
active not recruiting Phase III Dermatology
Study With Elranatamab Versus Lenalidomide in Patients With Newly Diagnosed Multiple Myeloma After Transplant
Elranatamab injections compared to lenalidomide tablets for newly diagnosed myeloma patients after stem cell transplant.
16 Apr 2026 NCT05317416
active not recruiting Phase III
Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)
New drug combination (sonrotoclax plus zanubrutinib) tested against standard treatment (venetoclax plus obinutuzumab) for chronic lymphocytic leukaemia.
16 Apr 2026 NCT06073821
● Recruiting Phase III
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Researchers tested whether a new migraine drug (BHV-3000) works better than placebo for treating severe migraines in young people.
16 Apr 2026 NCT04649242
● Recruiting Phase III
Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B
CSL222 Trial Summary CSL222 gene therapy tested in teenage boys with moderate-to-severe hemophilia B for safety, tolerability, and effectiveness.
16 Apr 2026 NCT07080905
active not recruiting Phase III Oncology
A Study to Learn More About How Well Elinzanetant Works and How Safe it is Compared to Placebo for the Treatment of Hot Flashes Caused by Anti-cancer Therapy in Women With, or at High Risk for Developing Hormone-receptor Positive Breast Cancer
Elinzanetant reduces hot flashes from cancer therapy in breast cancer patients better than placebo.
16 Apr 2026 NCT05587296
active not recruiting Phase III Oncology
Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib
Patients benefiting from olaparib in previous cancer trials can continue receiving it under this extension study.
16 Apr 2026 NCT04421963
● Recruiting Phase III
Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)
What is being tested: Ravulizumab, a complement C5 inhibitor, is being evaluated against placebo for its ability to reduce proteinuria and slow decline in…
16 Apr 2026 NCT06291376
● Recruiting Phase III Respiratory / COPD / Asthma
A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn’s Disease (CD)
What is being tested: Long-term safety and efficacy of vedolizumab (an anti-α4β7 integrin monoclonal antibody) as maintenance therapy in paediatric patients with moderate-to-severe ulcerative…
16 Apr 2026 NCT05442567
● Recruiting Phase III Oncology
JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer
What is being tested: A comparison of stereotactic ablative radiotherapy (SAbR) versus surgical sublobar resection (SR) to determine which approach provides superior survival outcomes…
16 Apr 2026 NCT02468024
● Recruiting Phase III Oncology
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)
What is being tested: Elranatamab, a bispecific antibody targeting BCMA and CD3, is being evaluated against standard treatments in relapsed/refractory multiple myeloma (RRMM) patients…
16 Apr 2026 NCT06152575
● Recruiting Phase III Cardiology / Cardiovascular
Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD
What is being tested: Pelacarsen (TQJ230), an antisense oligonucleotide therapy designed to lower lipoprotein(a) (Lp(a)), is being evaluated for efficacy and safety in patients…
16 Apr 2026 NCT06813911
● Recruiting Phase III Oncology
A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
What is being tested: Sacituzumab tirumotecan (MK-2870), an antibody-drug conjugate, as maintenance therapy either alone or combined with bevacizumab, compared to standard of care…
16 Apr 2026 NCT06824467
● Recruiting Phase III Oncology
Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer
What is being tested: T-DXd (trastuzumab deruxtecan) combined with rilvegostomig or as monotherapy, compared against standard-of-care gemcitabine plus cisplatin with durvalumab in treatment-naïve patients…
16 Apr 2026 NCT06467357
● Recruiting Phase III Oncology
A Study of BGB-16673 Compared to Investigator’s Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors
What is being tested: BGB-16673, a novel therapeutic agent, is being evaluated against standard investigator-selected treatments (idelalisib, bendamustine, or venetoclax—each combined with rituximab) in…
16 Apr 2026 NCT06846671
● Recruiting Phase III Oncology
Study to Evaluate INCB123667 Versus Investigator’s Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
What is being tested: INCB123667, a targeted therapy, is being compared against standard chemotherapy regimens in patients with platinum-resistant ovarian cancer specifically selected for…
16 Apr 2026 NCT07214779
● Recruiting Phase III Oncology
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
What is being tested: Palazestrant (an oral selective oestrogen receptor degrader) combined with ribociclib (CDK4/6 inhibitor) versus the standard treatment of letrozole (aromatase inhibitor)…
16 Apr 2026 NCT07085767
active not recruiting Phase III Oncology
Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer
Ongoing access to darolutamide for prostate cancer patients who benefited from previous trials, with continued monitoring.
15 Apr 2026 NCT04464226
● Recruiting Phase III Neurology
A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)
DEEP SEA Study Summary LP352 tested against placebo to reduce seizures in children and adults with Dravet syndrome over 24 months.
15 Apr 2026 NCT06660394
● Recruiting Phase III Oncology
Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)
Treatment Being Tested: Tarlatamab (a DLL3-targeting bispecific antibody) versus placebo administered after standard chemoradiotherapy in patients with limited-stage small-cell lung cancer, with primary efficacy…
15 Apr 2026 NCT06117774
● Recruiting Phase III Oncology
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
What is being tested: Sonrotoclax (a novel BCL2 inhibitor) combined with monoclonal antibodies (obinutuzumab or rituximab) versus the established standard treatment venetoclax plus rituximab…
15 Apr 2026 NCT06943872
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
What is being tested: Tezepelumab, a thymic stromal lymphopoietin (TSLP) inhibitor monoclonal antibody, is being evaluated for efficacy and safety in adult patients with…
14 Apr 2026 NCT06883305