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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase I Cardiology / Cardiovascular
A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies
What is being tested: BGB-16673 is a novel investigational agent being evaluated in a dose-escalation and expansion study to determine safe and effective dosing…
15 Apr 2026 NCT05006716
● Recruiting Phase II Cardiology / Cardiovascular
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
What is being tested: Pelacarsen (TQJ230), a subcutaneous antisense oligonucleotide that lowers lipoprotein(a), is being evaluated against placebo to determine whether reducing Lp(a) levels…
15 Apr 2026 NCT05646381
● Recruiting Oncology
Met Non Small Cell Cancer Registry (MOMENT)
What is being tested: MOMENT is a prospective multi-national disease registry collecting standardized longitudinal data on non-small cell lung cancer (NSCLC) treatment patterns and…
15 Apr 2026 NCT05376891
● Recruiting Phase IV Oncology
Acalabrutinib Monotherapy vs Investigator’s Choice of Treatment in Patients With CL Leukaemia and Heart Failure
What is being tested: Acalabrutinib monotherapy (100 mg twice daily) versus investigator's choice of alternative treatment in a Phase IV randomised trial evaluating safety…
15 Apr 2026 NCT06651970
● Recruiting Phase III Oncology
Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)
Treatment Being Tested: Tarlatamab (a DLL3-targeting bispecific antibody) versus placebo administered after standard chemoradiotherapy in patients with limited-stage small-cell lung cancer, with primary efficacy…
15 Apr 2026 NCT06117774
● Recruiting Phase III Oncology
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
What is being tested: Sonrotoclax (a novel BCL2 inhibitor) combined with monoclonal antibodies (obinutuzumab or rituximab) versus the established standard treatment venetoclax plus rituximab…
15 Apr 2026 NCT06943872
● Recruiting
Influence of Perfluorocarbon Liquid (LIQUID) During Pars Plana Vitrectomy on Retinal Vessel Displacement in Primary Macula-involving Rhegmatogenous Retinal Detachment
Study examines whether using perfluorocarbon liquid during retinal detachment surgery affects post-operative retinal vessel shifting and vision outcomes.
14 Apr 2026 NCT07027098
● Recruiting Phase I / Phase II
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Early-stage trial testing a new oral drug (nuvisertib) for safety and effectiveness in myelofibrosis patients.
14 Apr 2026 NCT04176198
active not recruiting Phase II Oncology
Fulvestrant, Ipatasertib and CDK4/6 Inhibition in Metastatic ER+/HER2- Breast Cancer Patients Without ctDNA Suppression
FAIM Trial Summary Adding ipatasertib to fulvestrant and palbociclib may improve survival in advanced hormone-receptor positive breast cancer patients without early treatment response.
14 Apr 2026 NCT04920708
active not recruiting Phase II Oncology
A Study to Test Long-term Treatment With Brigimadlin in People With Solid Tumours Who Took Part in a Previous Study With This Medicine
Adults who previously tolerated brigimadlin continue taking tablets every three weeks to assess long-term safety and tumour response.
14 Apr 2026 NCT06619509
● Recruiting
Clinical and Molecular Studies in Families With Inherited Eye Disease
Study identifying genetic causes of inherited eye diseases through clinical examination, electrical eye testing, and blood/saliva genetic analysis.
14 Apr 2026 NCT02771236
active not recruiting Oncology
Does Screening With the Galleri Test in the NHS Reduce the Likelihood of a Late-stage Cancer Diagnosis in an Asymptomatic Population? A Randomised Clinical Trial
Blood test screening alongside standard NHS testing detected more early-stage cancers and fewer late-stage cancers in asymptomatic adults.
14 Apr 2026 NCT05611632
● Recruiting Phase II
Long-term Safety and Efficacy Evaluation of Lunsekimig in Adult Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Completed a Previous Lunsekimig CRSwNP Study
Long-term safety and efficacy study of lunsekimig (a new treatment) in adults with poorly controlled chronic rhinosinusitis with nasal polyps over 52 weeks.
14 Apr 2026 NCT06914908
● Recruiting Respiratory / COPD / Asthma
Eosinopenia in Severe COPD Exacerbation
What is being tested: This observational study investigates the causes and recovery patterns of eosinopenia (abnormally low blood eosinophil counts) in patients hospitalised with…
14 Apr 2026 NCT06188065
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
What is being tested: Tezepelumab, a thymic stromal lymphopoietin (TSLP) inhibitor monoclonal antibody, is being evaluated for efficacy and safety in adult patients with…
14 Apr 2026 NCT06883305
● Recruiting Phase IV Cardiology / Cardiovascular
Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial Fibrillation Occurring Transiently With Stress
What is being tested: Oral anticoagulation therapy compared to no anticoagulation for stroke prevention in patients with stress-induced transient atrial fibrillation who have additional…
14 Apr 2026 NCT03968393
● Recruiting Phase III Cardiology / Cardiovascular
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
Drug being tested: Mavorixafor, a CXCR4 antagonist, is being evaluated for efficacy, safety and tolerability in patients with chronic neutropenic disorders (both congenital and…
14 Apr 2026 NCT06056297
● Recruiting Phase I Oncology
A Phase 1/1b Study of IAM1363 in HER2 Cancers
What is being tested: IAM1363, a novel therapeutic agent, is undergoing Phase 1/1b evaluation to assess its safety profile and preliminary efficacy in patients…
14 Apr 2026 NCT06253871
● Recruiting Phase III Oncology
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
What is being tested: Amivantamab (a bispecific antibody) combined with standard chemotherapy (mFOLFOX6 or FOLFIRI) versus the current standard treatment of cetuximab plus chemotherapy…
14 Apr 2026 NCT06662786
● Recruiting Phase III Oncology
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
What is being tested: Amivantamab (a bispecific antibody targeting EGFR and MET) combined with FOLFIRI chemotherapy, compared to the standard treatment of cetuximab/bevacizumab with…
14 Apr 2026 NCT06750094
● Recruiting Phase I Oncology
Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer
Treatment Being Tested: Gedatolisib (a PI3K/mTOR inhibitor) combined with darolutamide (an androgen receptor antagonist) in metastatic castration-resistant prostate cancer, with dose-finding and efficacy evaluation…
14 Apr 2026 NCT06190899
● Recruiting Phase I Oncology
A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer
What is being tested: A phase 1/2 dose-escalation study investigating the combination of two investigational drugs—Pasritamig (JNJ-78278343) and JNJ-86974680—to identify the optimal tolerated dose…
14 Apr 2026 NCT07319871
● Recruiting Phase I Oncology
Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection
What is being tested: (177Lu) rhPSMA-10.1 is a radioligand therapy targeting PSMA-expressing tumours in metastatic castrate-resistant prostate cancer, with evaluation of optimal dosing, safety…
14 Apr 2026 NCT05413850
● Recruiting Phase III Oncology
A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
Treatment being tested: Pasritamig (a novel therapeutic agent) combined with docetaxel chemotherapy versus docetaxel alone in metastatic castration-resistant prostate cancer (mCRPC), with primary endpoint…
14 Apr 2026 NCT07225946
● Recruiting Phase I Oncology
A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer
What is being tested: A Phase 1b/2 dose-escalation study evaluating the combination of two investigational agents (JNJ-78278343 and JNJ-95298177) in prostate cancer, with Part…
14 Apr 2026 NCT07082920
● Recruiting Phase II Oncology
A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study
What is being tested: Long-term safety monitoring of enzalutamide in prostate cancer patients who are continuing to benefit from treatment in previous Astellas or…
14 Apr 2026 NCT02960022
● Recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
What is being tested: Divarasib (a KRAS G12C inhibitor) combined with pembrolizumab (immunotherapy) versus standard chemotherapy (pemetrexed plus carboplatin or cisplatin) combined with pembrolizumab…
14 Apr 2026 NCT06793215
● Recruiting Phase II Oncology
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
What is being tested: Amivantamab (a bispecific antibody targeting EGFR and MET) administered subcutaneously with recombinant human hyaluronidase in combination regimens, primarily for advanced/metastatic…
14 Apr 2026 NCT05498428
● Recruiting Phase II Oncology
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Treatment being tested: Amivantamab (a bispecific antibody) combined with either lazertinib (a third-generation EGFR tyrosine kinase inhibitor) or platinum-based chemotherapy in patients with EGFR-mutated…
14 Apr 2026 NCT06667076
● Recruiting Phase II Oncology
To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer
What is being tested: Inavolisib (a PI3K inhibitor) combined with fulvestrant (an oestrogen receptor degrader) in patients with PIK3CA-mutated, hormone receptor-positive, HER2-negative locally advanced…
14 Apr 2026 NCT07368998
● Recruiting Phase I Oncology
Study of INCB123667 in Subjects With Advanced Solid Tumors
Drug Being Tested: INCB123667 is a novel investigational agent being evaluated for safety, tolerability, pharmacokinetics, and anti-tumour efficacy in advanced/metastatic solid tumours, tested both…
14 Apr 2026 NCT05238922
● Recruiting Neurology
Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
What is being tested: Real-world outcomes and effectiveness of Boston Scientific's Vercise DBS System for Parkinson's disease treatment, including the role of Image Guided…
14 Apr 2026 NCT02071134
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
What is being tested: Finerenone (a non-steroidal mineralocorticoid receptor antagonist) safety and tolerability in children and young adults aged 1-18 years with chronic kidney…
14 Apr 2026 NCT05457283
● Recruiting Phase III
A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression
What is being tested: Sefaxersen (RO7434656), a novel antisense oligonucleotide therapy designed to reduce kidney disease progression in patients with primary IgA nephropathy who…
14 Apr 2026 NCT05797610
● Recruiting Phase III
Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN
What is being tested: Long-term efficacy, safety and tolerability of iptacopan, a Factor B inhibitor targeting the alternative complement pathway, in patients with C3…
14 Apr 2026 NCT03955445
● Recruiting Phase III Rheumatology
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
Treatment being tested: Long-term safety and efficacy of guselkumab (an IL-23 inhibitor administered subcutaneously) in pediatric patients with moderately to severely active ulcerative colitis,…
14 Apr 2026 NCT06663332
● Recruiting Phase II Rheumatology
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn’s Disease
Investigational agent: TAK-279, a novel therapeutic agent, is being tested for its efficacy and safety in reducing bowel inflammation specifically in patients with moderately…
14 Apr 2026 NCT06233461
● Recruiting Phase III Rheumatology
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
What is being tested: Oral icotrokinra, a novel therapeutic agent, is being evaluated for its efficacy, safety, and tolerability in treating moderately to severely…
14 Apr 2026 NCT07196748
● Recruiting Respiratory / COPD / Asthma
Biologics and Paediatric Enteral Nutrition in Crohn’s Disease Study
What is being tested: This study evaluates the effectiveness and safety of biologic medications (injectable drugs targeting inflammation) compared to enteral nutrition therapy (specialised…
14 Apr 2026 NCT07522528
● Recruiting Respiratory / COPD / Asthma
The PARS Study: Paediatric Advanced Respiratory Service Study – An Observational Diagnostic Feasibility Study
What is being tested: The feasibility of using advanced diagnostic investigations (adapted for smaller patient size and improved tolerability) to identify sleep-disordered breathing in…
14 Apr 2026 NCT06292299
● Recruiting Respiratory / COPD / Asthma
Using Multiomics to Define Mechanisms of Rhinovirus-induced Chronic Obstructive Pulmonary Disease Exacerbations to Develop Novel Therapies and Therapeutic Targets
What is being tested: Multi-omics analysis of rhinovirus-induced COPD exacerbations to identify underlying biological mechanisms and develop novel therapeutic targets and treatments for this…
14 Apr 2026 NCT07112235
● Recruiting Respiratory / COPD / Asthma
Capillary OGTT Study
What is being tested: Capillary (fingerprick) oral glucose tolerance testing (OGTT) as an alternative to venous blood sampling for identifying stage 2 type 1…
14 Apr 2026 NCT06815081
● Recruiting Phase III Cardiology / Cardiovascular
A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE
What is being tested: Milvexian, a Factor XIa inhibitor, is being evaluated as a novel anticoagulant to reduce recurrent ischemic stroke risk compared to…
14 Apr 2026 NCT05702034
● Recruiting Cardiology / Cardiovascular
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
What is being tested: Long-term safety, performance, and functional outcomes of the Indigo Aspiration System, a mechanical thrombectomy device designed to remove blood clots…
14 Apr 2026 NCT04798261
● Recruiting Phase III Cardiology / Cardiovascular
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Intervention being tested: Treprostinil palmitil inhalation powder (TPIP) administered once daily for 24 weeks as a potential treatment for pulmonary hypertension associated with interstitial…
14 Apr 2026 NCT07179380
● Recruiting Phase I Oncology
An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)
Treatment being tested: A combination of two novel agents—tulmimetostat (DZR123), a targeted therapy, and JSB462 (luxdegalutamide), a GLP-1 receptor agonist—evaluated against standard of care…
14 Apr 2026 NCT07206056
● Recruiting Phase II Oncology
A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)
What is being tested: JNJ-90301900 (an investigational immunotherapy agent) combined with standard concurrent platinum-based chemotherapy and radiation therapy, followed by consolidation immunotherapy, to determine…
14 Apr 2026 NCT06667908
● Recruiting Phase I Oncology
Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer
BNT116 is a first-in-human immunotherapy being evaluated as monotherapy and in combination regimens for advanced non-small cell lung cancer (NSCLC), with the primary aim…
14 Apr 2026 NCT05142189
● Recruiting Phase III Oncology
A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)
What is being tested: BMS-986393 (arlo-cel), a novel therapeutic agent, is being compared against standard treatment regimens in patients with relapsed or refractory multiple…
14 Apr 2026 NCT06615479
● Recruiting Phase III Oncology
ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors
What is being tested: ONC-392 (gotistobart), a next-generation anti-CTLA-4 antibody, is being compared against standard docetaxel chemotherapy in patients with metastatic non-small cell lung…
14 Apr 2026 NCT05671510