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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2240 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2240 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase I Oncology
Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma
What is being tested: TGX-007, an AAV-mediated dual-payload gene therapy delivered directly into brain tumours to establish safety, optimal biological dose, and efficacy in…
04 May 2026 NCT07346144
● Recruiting Diabetes / Metabolic
Assessing the Dose-response of Muscle Protein Synthesis to “Super-whey” in Older Adults
One-sentence summary: This study tests three doses of leucine-enriched whey protein to find which best stimulates muscle building in older people.
01 May 2026 NCT05700058
● Recruiting Phase III Rheumatology
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
Dapirolizumab pegol added to standard treatment improves moderate to severe lupus disease activity.
01 May 2026 NCT06617325
● Recruiting Gastroenterology
Drivers and Barriers for Adopting Healthy and Sustainable Food Swaps in Young
Study tests whether personalised approaches help young adults swap red meat for fish or plants, improving health markers.
01 May 2026 NCT06714656
● Recruiting Gastroenterology
Fast Food Online Delivery Purchase Behaviour in the Presence and Absence of Price-based Incentives
Removing price discounts from fast food delivery apps slightly reduced calorie selections, but effects were unclear and based on hypothetical choices only.
01 May 2026 NCT07368881
active not recruiting Phase III Oncology
Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)
Adding pembrolizumab immunotherapy to chemoradiotherapy improves survival and delays cancer progression in muscle-invasive bladder cancer patients avoiding surgery.
01 May 2026 NCT04241185
active not recruiting Phase III Gastroenterology
Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)
Elafibranor tested against placebo in PBC patients inadequately responding to ursodeoxycholic acid, assessing alkaline phosphatase reduction and safety.
01 May 2026 NCT04526665
active not recruiting Phase III Oncology
Study of Durvalumab With Tremelimumab Versus SoC as 1st Line Therapy in Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE)
Two immunotherapy drugs versus standard chemotherapy for advanced lung cancer without specific genetic mutations.
01 May 2026 NCT02542293
active not recruiting Phase III Neurology
A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis
Long-term safety and efficacy study of ocrelizumab, a B-cell depleting antibody, in multiple sclerosis patients continuing from previous trials.
01 May 2026 NCT05269004
● Recruiting
Prospective Follow-up of the Prevision Hip Stem With Comparison of Different Implant Variants
Long-term safety and performance study of different Prevision hip stem variants in routine clinical practice.
01 May 2026 NCT06626490
active not recruiting Phase III Mental Health / Psychiatry
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)
MM120 was tested against placebo for anxiety disorder in a large, rigorous trial with long-term follow-up.
01 May 2026 NCT06809595
● Recruiting Phase I Oncology
A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs
What is being tested: AZD9750, a novel investigational agent, is being evaluated as monotherapy and in combination with saruparib (a PARP inhibitor) in metastatic…
01 May 2026 NCT07336446
● Recruiting Phase I Neurology
A Study of AZD0120 in Autoimmune Diseases
What is being tested: AZD0120, a dual-targeting CAR+ T-cell therapy that simultaneously targets BCMA and CD19, is being evaluated for safety and tolerability in…
01 May 2026 NCT07295847
● Recruiting Phase II
Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus
What is being tested: Safety and tolerability of difelikefalin, a novel therapeutic agent, in adolescent patients undergoing haemodialysis who experience moderate-to-severe pruritus (a significant…
01 May 2026 NCT06593392
● Recruiting Phase II Gastroenterology
A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)
Treatment being tested: ALG-000184, a novel oral antiviral agent administered once daily as monotherapy, compared against the established standard tenofovir disoproxil fumarate (TDF) in…
01 May 2026 NCT06963710
● Recruiting Phase I Cardiology / Cardiovascular
A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
What is being tested: FT819, a novel therapeutic agent targeting B-cell activity, is being evaluated for safety, pharmacokinetics, and anti-B-cell efficacy in patients with…
01 May 2026 NCT06308978
● Recruiting Cardiology / Cardiovascular
The Next Leap in Cardiac Magnetic Resonance Imaging:Cycling the Field
What is being tested: Development and clinical validation of a custom-built cardiac coil designed specifically for a whole-body Field-Cycling MRI (FFC-MRI) prototype to enable…
01 May 2026 NCT04458883
● Recruiting Phase II Cardiology / Cardiovascular
Coronary Artery Stents in Heart Failure With Preserved Ejection Fraction
What is being tested: This trial evaluates whether coronary artery stent placement improves outcomes in patients with HFpEF who have concurrent coronary artery disease,…
01 May 2026 NCT07560436
● Recruiting Cardiology / Cardiovascular
Multicentre Hypertrophic Cardiomyopathy Registry
What is being tested: A multicentre registry collecting comprehensive clinical data on hypertrophic cardiomyopathy patients to understand disease progression, phenotypes, and outcomes across diverse…
01 May 2026 NCT07381894
● Recruiting Phase I Oncology
Clinical Study to Assess the Safety and Efficacy of the SpectraCure P18 System
What is being tested: The SpectraCure P18 System combined with verteporfin (a photosensitizer) is being evaluated for safety, efficacy, and optimal dosing parameters in…
01 May 2026 NCT03067051
● Recruiting Phase II Oncology
A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement
Drug and target: Lirafugratinib, a selective FGFR2 inhibitor, is being tested in previously treated patients with advanced/metastatic solid tumours (excluding cholangiocarcinoma) that harbour FGFR2…
01 May 2026 NCT07359820
● Recruiting Phase II Oncology
A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer
What is being tested: ASP5541, a novel androgen receptor pathway inhibitor (ARPI), is being evaluated in a Phase 2 study as a potential treatment…
01 May 2026 NCT07005154
active not recruiting Phase III Gastroenterology
A Study of Elafibranor in Adults With Primary Biliary Cholangitis and Inadequate Response or Intolerance to Ursodeoxycholic Acid.
Trial testing elafibranor versus placebo in primary biliary cholangitis patients who cannot tolerate or inadequately respond to ursodeoxycholic acid, measuring effects on alkaline phosphatase…
30 Apr 2026 NCT06383403
active not recruiting Phase III
A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment
Two new PNH drugs (pozelimab + cemdisiran) tested for safety and effectiveness against existing complement inhibitor treatments.
30 Apr 2026 NCT05133531
active not recruiting
ADH1 and ADH2 Disease Monitoring Study (DMS)
Study tracking how autosomal dominant hypocalcaemia types 1 and 2 develop and progress over time using patient medical records.
30 Apr 2026 NCT05227287
● Recruiting Phase I Dermatology
A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis
Early-stage trial testing new drug SYX-5219 for safety and effectiveness in healthy people and atopic dermatitis patients.
30 Apr 2026 NCT07558668
● Recruiting
Diagnostic Accuracy of Oral Images, OPGs, Biomarkers and Questionnaires vs. Clinical Assessment for Periodontal Disease (PostNCT07164573)
Study tests whether photos, scans, saliva tests and questionnaires can accurately detect gum disease compared to clinical examination.
30 Apr 2026 NCT07406867
● Recruiting Gastroenterology
VertiGreens Investigating the Effects of Iron Biofortification of Microgreens on Iron Status in Women
Iron-enriched microgreens in smoothies for 28 days improve iron levels in women, assessed via blood tests and dietary tracking.
30 Apr 2026 NCT06972927
active not recruiting Phase II
A Study to Evaluate RO7204239 in Participants With Facioscapulohumeral Muscular Dystrophy
A study testing a new antibody drug to block myostatin in adults with facioscapulohumeral muscular dystrophy.
30 Apr 2026 NCT05548556
active not recruiting Diabetes / Metabolic
The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema
Real-world study collecting data on vision outcomes in patients with wet macular degeneration or diabetic eye swelling treated with aflibercept 8mg injections.
30 Apr 2026 NCT06075147
active not recruiting Phase IV
A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration
Faricimab injections given every 24 weeks or less maintain vision in treatment-naive wet age-related macular degeneration over 100 weeks.
30 Apr 2026 NCT06795048
active not recruiting Oncology
A Study of the Effectiveness of Cabozantinib in Combination With Nivolumab as First-line Treatment of Advanced Renal Cell Carcinoma (aRCC) in Adults
Cabozantinib plus nivolumab as first-line treatment for advanced kidney cancer: real-world safety and effectiveness study.
30 Apr 2026 NCT05361434
● Recruiting Phase III Oncology
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician’s Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Treatment being tested: Sacituzumab govitecan-hziy (an antibody-drug conjugate targeting Trop-2) combined with pembrolizumab (PD-L1 inhibitor) versus physician's choice treatment in the adjuvant setting following…
30 Apr 2026 NCT05633654
● Recruiting Oncology
Sodium-glucose Transporter Type 2 Inhibition in Anthracycline-related Cardiotoxicity
What is being tested: SGLT2 inhibitors are being investigated as a potential preventive or therapeutic intervention for anthracycline-induced cardiotoxicity, a serious heart damage complication…
30 Apr 2026 NCT07070765
● Recruiting Gastroenterology
Drug-induced Liver Injury: Itching Study
What is being tested: The study investigates itching (pruritus) associated with drug-induced liver injury (DILI), specifically focusing on cholestatic or mixed-pattern hepatic reactions—an unpredictable…
30 Apr 2026 NCT06446609
● Recruiting Phase III Oncology
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen
What is being tested: Paltusotine, an oral daily medication, is being evaluated against placebo in a Phase 3 randomized controlled trial to assess its…
30 Apr 2026 NCT07087054
● Recruiting Phase III Oncology
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients
Treatment Being Tested: Ivonescimab (a dual TIGIT/PD-L1 pathway inhibitor) combined with chemotherapy compared to pembrolizumab (PD-L1 inhibitor) combined with chemotherapy as first-line therapy for…
30 Apr 2026 NCT05899608
● Recruiting Cardiology / Cardiovascular
Rebalancing the Fat Content of the Heart and Muscles
What is being tested: Semaglutide's effects on reducing fat accumulation in the heart and skeletal muscles, beyond its traditional role in blood sugar control…
30 Apr 2026 NCT07065383
● Recruiting Cardiology / Cardiovascular
Manganese-enhanced Magnetic Resonance Imaging (MEMRI) in Heart Failure With Preserved Ejection Fraction
What is being tested: Manganese-enhanced Magnetic Resonance Imaging (MEMRI) as a novel imaging technique to visualise cardiac function and myocardial viability in heart failure…
30 Apr 2026 NCT06652763
● Recruiting Phase III Cardiology / Cardiovascular
Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)
Treatment being tested: ADX-324 is a novel therapy being evaluated for long-term safety and efficacy in hereditary angioedema (HAE) Types I and II, building…
30 Apr 2026 NCT07428499
● Recruiting Cardiology / Cardiovascular
The Role of Epicardial Adiposity in Heart Failure With Preserved Ejection Fraction
What is being tested: The relationship between epicardial adiposity (fat surrounding the heart) and heart failure with preserved ejection fraction (HFpEF), using advanced imaging…
30 Apr 2026 NCT06768437
● Recruiting Cardiology / Cardiovascular
Is There a Genetic Predisposition for Acute Stress-induced (Takotsubo) Cardiomyopathy
What is being tested: The study investigates whether genetic factors predispose certain individuals to developing takotsubo cardiomyopathy (stress-induced cardiomyopathy), rather than this condition occurring…
30 Apr 2026 NCT04513054
● Recruiting Cardiology / Cardiovascular
Non-invasive Diagnosis of Coronary Microvascular Disease: Pilot Study
What is being tested: Non-invasive diagnostic methods to identify coronary microvascular disease (CMD) in patients with angina symptoms but no significant blockage in main…
30 Apr 2026 NCT06070662
● Recruiting Phase III Oncology
A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)
What is being tested: AZD0120, a dual-targeted CAR-T cell therapy targeting both BCMA and CD19 antigens, is being compared against standard chemotherapy regimens (daratumumab-based…
30 Apr 2026 NCT07391657
● Recruiting Phase III Oncology
Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML
What is being tested: Quizartinib (a FLT3 inhibitor) plus standard chemotherapy versus placebo plus chemotherapy in newly diagnosed FLT3-ITD negative AML patients to determine…
30 Apr 2026 NCT06578247
● Recruiting Phase I Oncology
LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve
What is being tested: EG-70 is an intravesical immunotherapy being evaluated for safety and efficacy in non-muscle invasive bladder cancer (NMIBC), with a Phase…
30 Apr 2026 NCT04752722
● Recruiting Phase III Oncology
A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
What is being tested: A randomised comparison of two triple-drug regimens—mezigdomide (a novel cereblon modulator) combined with bortezomib and dexamethasone versus the established pomalidomide…
30 Apr 2026 NCT05519085
active not recruiting Phase III
A Randomized, Double-blind 2-arm, Followed by an Open-label 1-arm, NEPTUNUS Extension Study to Assess the Long-term Safety and Efficacy of Ianalumab in Patients With Sjogrens Syndrome.
Long-term safety and effectiveness study of ianalumab, a new drug treatment for patients with Sjögren's syndrome.
29 Apr 2026 NCT05985915
● Recruiting Phase II
EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)
Alpelisib (a targeted drug) tested in children and adults with PIK3CA gene mutations causing abnormal tissue overgrowth.
29 Apr 2026 NCT06997588
● Recruiting Phase III
Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN
Iptacopan reduces kidney damage better than placebo in patients with a specific type of glomerulonephritis.
29 Apr 2026 NCT05755386