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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2240 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2240 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase III
A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia
Study testing intravenous efgartigimod versus placebo in adults with immune thrombocytopenia to assess effectiveness and safety.
29 Apr 2026 NCT06544499
● Recruiting Phase III
A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine
Xeomin injections tested against placebo for reducing monthly migraine days in chronic migraine patients over one year.
29 Apr 2026 NCT07018713
active not recruiting Phase III Neurology
A Phase 3 Study to Examine the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder.
ZX008 reduced seizures in children and adults with CDKL5 deficiency disorder compared to placebo.
29 Apr 2026 NCT05064878
active not recruiting Phase III Dermatology
A 52-Week Study to Learn About the Safety and Effects of Ritlecitinib in Participants With Nonsegmental Vitiligo
52-week trial testing whether continuing or increasing ritlecitinib dosing maintains or improves skin pigmentation recovery in non-segmental vitiligo patients.
29 Apr 2026 NCT06163326
active not recruiting Phase II Oncology
A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancer
Three immunotherapy combinations tested in chemotherapy-ineligible patients with advanced bladder cancer: LAG-3 alone, LAG-3 plus TIGIT inhibitor, versus PD-L1 inhibitor.
29 Apr 2026 NCT05645692
● Recruiting Phase IV
Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants
Long-term follow-up of an eye implant treatment for MacTel type 2, including patients who previously received sham surgery.
29 Apr 2026 NCT06971939
active not recruiting
PERIGON Pivotal Trial
PERIGON Trial Summary Study testing whether a new artificial heart valve (Model 400) is safe and effective for patients needing aortic valve replacement.
29 Apr 2026 NCT02088554
● Recruiting Phase II Rheumatology
FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis
Intervention being tested: Faecal Microbiota Transplant (FMT) versus placebo in patients with primary sclerosing cholangitis (PSC), a rare autoimmune liver disease with no established…
29 Apr 2026 NCT06286709
● Recruiting Phase I Respiratory / COPD / Asthma
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
What is being tested: LTP001 is a novel investigational treatment being evaluated in a two-part study: Part A assesses safety and tolerability in healthy…
29 Apr 2026 NCT06649110
● Recruiting Phase I Respiratory / COPD / Asthma
A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants
GSK4527363 is a novel investigational agent being evaluated for safety, tolerability, and pharmacokinetic/pharmacodynamic properties across healthy volunteers and patients with SLE and connective tissue…
29 Apr 2026 NCT06576271
● Recruiting Phase II Respiratory / COPD / Asthma
An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)
What is being tested: Long-term safety and efficacy outcomes of Avalyn's inhaled antifibrotic agent (AP01) in participants who previously completed earlier phase trials, using…
29 Apr 2026 NCT06951217
● Recruiting Cardiology / Cardiovascular
Hypertension Management in Young Adults Personalised by Echocardiography and Clinical Outcome.
What is being tested: Baseline transthoracic echocardiography combined with routine hypertension clinic data to guide personalised management and improve cardiovascular risk stratification in young…
29 Apr 2026 NCT03762499
● Recruiting Cardiology / Cardiovascular
Hypertension Explored in Long-term Postpartum Follow-up in Later Life
What is being tested: The study investigates the long-term cardiovascular mechanisms linking hypertensive pregnancy disorders (gestational hypertension and preeclampsia) to increased risk of chronic…
29 Apr 2026 NCT06187012
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
What is being tested: Finerenone (a non-steroidal mineralocorticoid receptor antagonist) versus placebo in hospitalized patients with acute decompensated heart failure, specifically targeting those with…
29 Apr 2026 NCT06008197
● Recruiting Cardiology / Cardiovascular
BoStOn SCientific Rhythm MAnagemenT REgiStry (SOCRATES)
What is being tested: SOCRATES is a post-market surveillance registry monitoring Boston Scientific's rhythm management devices (pacemakers, defibrillators, and related systems) to evaluate real-world…
29 Apr 2026 NCT04823663
● Recruiting Cardiology / Cardiovascular
Clinical Antenatal Randomised Study to CharactErise Key Roles of TetrahydroFOLate in HyperTensive Pregnancies
What is being tested: The role of tetrahydrofolate (active folate) supplementation in reducing adverse outcomes in pregnant women with hypertension, investigating whether enhanced folate…
29 Apr 2026 NCT05434195
● Recruiting Phase III Oncology
Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
Intervention being tested: Sacituzumab govitecan (an antibody-drug conjugate targeting Trop-2) compared against standard of care chemotherapy in patients with previously treated extensive-stage small cell…
29 Apr 2026 NCT06801834
● Recruiting Phase I Oncology
A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A)
Treatment being tested: Investigational agents administered alone or in combination with pembrolizumab (a PD-1 inhibitor) in patients with PD-1/L1-refractory urothelial carcinoma, addressing an unmet…
29 Apr 2026 NCT05562830
● Recruiting Phase III Oncology
Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations
What is being tested: Datopotamab deruxtecan (Dato-DXd), a TROP2-targeted antibody-drug conjugate, is being compared against standard docetaxel chemotherapy in previously treated advanced/metastatic non-squamous NSCLC…
29 Apr 2026 NCT07291037
● Recruiting Phase III
Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation
Ravulizumab drug reduced need for dialysis after kidney transplant compared to placebo in high-risk patients.
28 Apr 2026 NCT06830798
● Recruiting Rheumatology
Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)
PROMISSE Study Summary Blood markers (complement products and antiangiogenic factors) may predict pregnancy complications in SLE and antiphospholipid syndrome patients.
28 Apr 2026 NCT00198068
● Recruiting Diabetes / Metabolic
Assessing the Impact of a Leucine Enriched Whey Protein vs Isonitrogenous Whey on Muscle Protein Synthetic Responses in the Rested and Acute Post Exercise States in Older Adults
Testing whether leucine-enriched whey protein boosts muscle protein production in older adults at rest and after exercise, compared to standard whey protein.
28 Apr 2026 NCT06971822
● Recruiting Phase III
A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)
Enlicitide added to rosuvastatin reduced cholesterol more than rosuvastatin alone in high cholesterol patients.
28 Apr 2026 NCT07216482
active not recruiting Phase I Oncology
A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer
Trial testing immune-boosting antibodies plus cetuximab for advanced head and neck cancer patients who've failed standard treatment.
28 Apr 2026 NCT05249426
active not recruiting Phase I Rheumatology
A Study to Test How Well BI 3000202 is Tolerated by People With Type 1 Interferonopathies
Drug BI 3000202 safety and tolerability trial in adults with type 1 interferonopathies including AGS, COPA, and FCL syndromes.
28 Apr 2026 NCT06878365
● Recruiting Phase II
A Clinical Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1
This trial tests whether a new medicine (PGN-EDODM1) is safe and works for people with myotonic dystrophy type 1.
28 Apr 2026 NCT06667453
● Recruiting Rare Diseases
Pompe Disease Registry Protocol
Global registry tracking Pompe disease progression and treatment outcomes in patients to improve diagnosis, monitoring, and therapeutic guidance.
28 Apr 2026 NCT00231400
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer’s Disease (ADEPT-2)
Treatment being tested: KarXT, a novel muscarinic M1/M4 receptor agonist, is being evaluated for treating psychosis (including hallucinations, delusions, and agitation) in patients with…
28 Apr 2026 NCT06126224
● Recruiting Cardiology / Cardiovascular
Brain Training to Improve Balance in Parkinson’s Disease
Intervention being tested: A brain training programme designed to improve balance function in people with Parkinson's disease, addressing one of the most disabling symptoms…
28 Apr 2026 NCT05986643
● Recruiting Oncology
IMMUNO-FIT Observational Study
What is being tested: The study investigates how immunotherapy (checkpoint inhibitors) affects physical fitness, quality of life, and treatment tolerance in adults with solid…
28 Apr 2026 NCT07354971
● Recruiting Phase II Cardiology / Cardiovascular
Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)
Drug being tested: REGN13335, an experimental therapeutic agent, is being evaluated for safety and efficacy in adults with pulmonary arterial hypertension (PAH), a condition…
28 Apr 2026 NCT07318597
● Recruiting Phase III Oncology
MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia Vera
Treatment being tested: Ruxolitinib (a JAK1/2 inhibitor) compared against standard first-line therapies (hydroxycarbamide or interferon-alpha) in newly diagnosed high-risk polycythemia vera patients. Patient eligibility…
28 Apr 2026 NCT04116502
● Recruiting Phase III Oncology
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator’s Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
What is being tested: Nemtabrutinib (MK-1026), a novel Bruton's tyrosine kinase (BTK) inhibitor, is being directly compared against standard-of-care BTK inhibitors (ibrutinib or acalabrutinib)…
28 Apr 2026 NCT06136559
● Recruiting Phase I Diabetes / Metabolic
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.
A new weight loss drug (AZD1043) is being tested for safety and effectiveness in overweight and obese adults.
27 Apr 2026 NCT07511205
● Recruiting
A Natural History Study in Participants With Congenital Myasthenic Syndromes (CMS) Due to Mutations in DOK7, MUSK, AGRN, or LRP4
Study tracking symptom changes and quality of life in patients with rare inherited muscle-nerve connection disorders caused by specific genetic mutations.
27 Apr 2026 NCT06078553
active not recruiting Phase II
Adagrasib in Patients With KRASG12C-mutant NSCLC Who Are Elderly or Have Poor Performance Status
Adagrasib showed benefit in elderly or unfit lung cancer patients with KRASG12C mutations who couldn't tolerate standard treatments.
27 Apr 2026 NCT05673187
● Recruiting Phase III Gastroenterology
Extension Study for the Port Delivery System With Ranibizumab (Portal)
Portal Extension Study Summary Implanted drug delivery system releasing ranibizumab shows sustained safety and effectiveness in wet age-related macular degeneration over extended follow-up.
27 Apr 2026 NCT03683251
● Recruiting
HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington’s Disease
HDClarity collects spinal fluid and blood samples from 2500 Huntington's disease patients to identify biomarkers for developing new treatments.
27 Apr 2026 NCT02855476
active not recruiting Phase II
A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases
A trial testing a new cell therapy (tabelecleucel) to treat diseases caused by Epstein-Barr virus infection.
27 Apr 2026 NCT04554914
● Recruiting Phase II / Phase III
A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation
Frexalimab injections compared to tacrolimus tablets in first kidney transplant patients over five years to assess effectiveness and safety.
27 Apr 2026 NCT07412470
● Recruiting Phase I / Phase II
A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK Inhibitors
Testing whether adding roginolisib to ruxolitinib safely improves outcomes in myelofibrosis patients who haven't responded to JAK inhibitors alone.
27 Apr 2026 NCT06887803
● Recruiting Phase III Rheumatology
OLE Study With Filgotinib in JIA
Filgotinib appears safe and effective for long-term use in children with polyarticular or systemic juvenile idiopathic arthritis.
27 Apr 2026 NCT07553182
active not recruiting Phase IV
A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis
Emicizumab treatment improves health, physical activity, and joint damage in teenagers and adults with moderate to severe haemophilia A.
27 Apr 2026 NCT05181618
active not recruiting Dermatology
A Proof-of-Concept Study to Evaluate the Efficacy of NOBO, a Novel Postbiotic, in Controlling Axillary Odor in Healthy Adults
Trial testing whether a yeast-based spray reduces underarm odor compared to placebo in healthy adults.
27 Apr 2026 NCT07547761
● Recruiting Gastroenterology
ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)
What is being tested: ELEVATE is a global registry documenting the natural disease progression of acute hepatic porphyria (AHP) and evaluating real-world safety and…
27 Apr 2026 NCT04883905
● Recruiting Phase III Cardiology / Cardiovascular
A Study of Roxadustat to Treat Anemia in Children and Teenagers With Chronic Kidney Disease
What is being tested: Roxadustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor already approved for treating anaemia in adult CKD patients, is being investigated…
27 Apr 2026 NCT05970172
● Recruiting Phase II Rheumatology
Obe-cel in Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis
What is being tested: Obe-cel, a B-cell targeted therapy designed to eliminate pathogenic B cells in patients with severe, refractory SLE and active lupus…
27 Apr 2026 NCT07053800
● Recruiting Phase III Infectious Disease
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
What is being tested: This Phase 3 trial compares two intravenous antiviral treatments—brincidofovir (BCV) and cidofovir (CDV)—for managing adenovirus (AdV) viremia in allogeneic hematopoietic…
27 Apr 2026 NCT07387367
● Recruiting Rheumatology
Describing Treatment Patterns and Creating an Updated Treatment Flow in an Ulcerative Colitis Population
What is being tested: This trial characterises current treatment patterns and pathways in ulcerative colitis management, developing an updated treatment algorithm to reflect contemporary…
27 Apr 2026 NCT07177209
● Recruiting Phase III Oncology
Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer
What is being tested: The trial evaluates whether adding stereotactic radiosurgery (SRS) to standard systemic immunotherapy or targeted therapy improves central nervous system progression-free…
27 Apr 2026 NCT05522660