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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

active not recruiting Phase III Oncology
A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer
Adding lurbinectedin to atezolizumab maintenance therapy versus atezolizumab alone for extensive-stage small-cell lung cancer after initial chemotherapy.
29 Jun 2026 NCT05091567
● Recruiting Phase III Cardiology / Cardiovascular
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
Treatment being tested: Sonlicromanol, a novel investigational medicine designed to reduce fatigue symptoms and improve physical function (including balance control) in patients with primary…
29 Jun 2026 NCT06451757
● Recruiting Phase III Cardiology / Cardiovascular
Study of Oral Deucrictibant XR Tablet for Prophylaxis and Deucrictibant IR Capsule for On-Demand Treatment of Angioedema Attacks in Adults With Acquired Angioedema Due to C1 Inhibitor Deficiency
What is being tested: Deucrictibant XR (extended-release) tablet for preventative treatment and deucrictibant IR (immediate-release) capsule for acute attack management in acquired angioedema due…
26 Jun 2026 NCT07266805
active not recruiting Phase III Rheumatology
A Study of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas (Scalp, Genital, and/or Palms of the Hands and the Soles of the Feet)
New drug JNJ-77242113 tested for treating psoriasis in difficult-to-treat areas like scalp, genitals, palms and soles.
25 Jun 2026 NCT06095102
● Recruiting Phase III Dermatology
A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis
Tralokinumab injections plus steroid cream safely and effectively treat moderate-to-severe eczema in young children and infants.
25 Jun 2026 NCT06311682
● Recruiting Phase III Diabetes / Metabolic
A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis
Efruxifermin tested against placebo in 1,650 patients with liver scarring from fatty liver disease (stages 2-3, non-cirrhotic).
25 Jun 2026 NCT06215716
● Recruiting Phase III Oncology
LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC
What is being tested: The combination of TTFields (tumour-treating fields) delivered via NovoTTF-200T device alongside pembrolizumab immunotherapy and platinum-based chemotherapy in patients with metastatic…
25 Jun 2026 NCT06216301
● Recruiting Phase III
A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy
Trial testing a new drug (volrustomig) versus monitoring in head and neck cancer patients after chemoradiotherapy.
24 Jun 2026 NCT06129864
● Recruiting Phase III
Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
This trial tests whether pridopidine slows ALS progression compared to placebo in adults over 96 weeks.
24 Jun 2026 NCT07322003
active not recruiting Phase III
A Study to Evaluate the Effect of Venglustat Tablets on Left Ventricular Mass Index in Male and Female Adult Participants With Fabry Disease
Venglustat compared to standard treatment for reducing heart thickening in adults with Fabry disease over 18 months.
24 Jun 2026 NCT05280548
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant
What is being tested: A novel combination therapy pairing elranatamab (a bispecific antibody engaging T-cells and myeloma cells) with daratumumab and lenalidomide, compared against…
24 Jun 2026 NCT05623020
active not recruiting Phase III
A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Non-Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-NTDT)
Mitapivat reduced anaemia in patients with non-transfusion-dependent thalassemia compared to placebo.
23 Jun 2026 NCT04770753
● Recruiting Phase III Mental Health / Psychiatry
NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Trial testing whether adding NBI-1065845 to existing depression treatment works better than placebo for improving symptoms.
23 Jun 2026 NCT06963021
● Recruiting Phase III Oncology
A Study of ZL-1310 Versus Investigator’s Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)
What is being tested: ZL-1310, a novel therapeutic agent, is being compared against standard investigator-selected treatments in patients with relapsed small cell lung cancer…
23 Jun 2026 NCT07218146
● Recruiting Phase III Diabetes / Metabolic
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Intervention being tested: Enicepatide (RO7795068), a dual GLP-1/GIP receptor agonist at multiple doses, compared with placebo for weight management and glycaemic control in patients…
23 Jun 2026 NCT07351058
● Recruiting Phase III Diabetes / Metabolic
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Treatment being tested: Enicepatide (RO7795068), a dual GLP-1/GIP receptor agonist, is being evaluated at multiple doses versus placebo for weight management efficacy and safety…
23 Jun 2026 NCT07351045
active not recruiting Phase III Oncology
Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing
Ongoing access to avelumab treatment for patients benefiting from it in completed Pfizer trials, with safety monitoring.
22 Jun 2026 NCT05059522
active not recruiting Phase II / Phase III Rheumatology
A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
Litifilimab injections tested for efficacy and safety in adults with active cutaneous lupus unresponsive to antimalarial therapy.
22 Jun 2026 NCT05531565
● Recruiting Phase III Neurology
A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
This trial tests whether inhaled alprazolam stops prolonged seizures faster than placebo in people aged 12+.
22 Jun 2026 NCT05077904
● Recruiting Phase III Oncology
A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)
What is being tested: Sacituzumab govitecan-hziyah (Sac-TMT), an antibody-drug conjugate targeting TROP-2, is being evaluated as a treatment option for advanced ovarian cancer patients…
22 Jun 2026 NCT07318558
active not recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy
New cancer drug inavolisib plus fulvestrant compared with alpelisib plus fulvestrant for advanced breast cancer resistant to previous treatments.
18 Jun 2026 NCT05646862
active not recruiting Phase III Oncology
A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer
Testing two immunotherapy combinations after chemotherapy and radiotherapy in advanced lung cancer patients.
18 Jun 2026 NCT05221840
● Recruiting Phase III Diabetes / Metabolic
Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
Treatment being tested: KAI-9531, a novel subcutaneous injection administered weekly, is being evaluated for its efficacy in reducing body weight compared to placebo in…
18 Jun 2026 NCT07284875
● Recruiting Phase III Cardiology / Cardiovascular
A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
What is being tested: Lepodisiran, an investigational therapy designed to reduce lipoprotein(a) [Lp(a)] levels, is being evaluated for its ability to reduce coronary artery…
18 Jun 2026 NCT07613294
● Recruiting Phase III Cardiology / Cardiovascular
Timing to Restart Direct Oral Anticoagulants After Traumatic Intracranial Haemorrhage
What is being tested: The optimal timing for restarting direct oral anticoagulants (DOACs) in older patients after traumatic intracranial haemorrhage, comparing early versus delayed…
18 Jun 2026 NCT06322953
● Recruiting Phase III Oncology
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)
Treatment being tested: Two immunotherapy-based regimens for advanced biliary tract cancer (BTC)—rilvegostomig combined with gemcitabine/cisplatin versus durvalumab combined with gemcitabine/cisplatin—compared as first-line therapy in…
18 Jun 2026 NCT07221253
active not recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician’s Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
Giredestrant versus standard hormone therapy for early breast cancer: a Phase III trial testing a new treatment option.
18 Jun 2026 NCT04961996
active not recruiting Phase III
Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren’s Syndrome
Trial testing whether ianalumab improves symptoms and safety in people with active Sjögren's syndrome compared to placebo.
18 Jun 2026 NCT05349214
active not recruiting Phase III Infectious Disease
Attachment Inhibitor Comparison in Heavily Treatment Experienced Patients
A new HIV drug (BMS-663068) tested in patients with resistant virus who have failed multiple previous treatments.
18 Jun 2026 NCT02362503
active not recruiting Phase III Diabetes / Metabolic
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
Retatrutide weekly injection tested to reduce heart attacks, strokes, and kidney damage in obese adults over five years.
18 Jun 2026 NCT06383390
active not recruiting Phase III Cardiology / Cardiovascular
A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIa AL Amyloidosis (CARES)
CAEL-101 antibody tested to remove amyloid deposits, improve survival and reduce heart hospitalisations in advanced light chain amyloidosis patients.
18 Jun 2026 NCT04512235
active not recruiting Phase III
A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment
Imetelstat improves survival compared to standard treatment in patients with advanced myelofibrosis who haven't responded to JAK inhibitors.
18 Jun 2026 NCT04576156
active not recruiting Phase III Dermatology
A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis
Ruxolitinib cream safely and effectively reduced moderate eczema in children and teenagers aged 6-17 years.
17 Jun 2026 NCT06832618
active not recruiting Phase III Gastroenterology
Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis
Tofacitinib tablet oral treatment for children aged 2-17 with moderate-severe ulcerative colitis, measuring remission rates after 44 weeks.
17 Jun 2026 NCT04624230
● Recruiting Phase III Oncology
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
Treatment being tested: Dato-DXd (a HER2-directed antibody-drug conjugate) combined with rilvegostomig (an immunostimulatory agent), versus rilvegostomig alone or pembrolizumab monotherapy, as first-line therapy for…
17 Jun 2026 NCT06357533
active not recruiting Phase III Infectious Disease
Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With Biktarvy
Trial comparing a new two-drug HIV combination against standard three-drug treatment in people with well-controlled infection.
15 Jun 2026 NCT06333808
active not recruiting Phase II / Phase III Oncology
A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Participants With PIK3CA-Mutant, Hormone Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer
Adding inavolisib to standard breast cancer treatment improves outcomes in patients with specific genetic mutations and advanced hormone-receptor-positive disease.
15 Jun 2026 NCT04191499
● Recruiting Phase III Neurology
Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder
Radiprodil versus placebo for rare genetic brain disorder causing seizures and developmental problems, with open-label extension.
12 Jun 2026 NCT07224581
● Recruiting Phase III Dermatology
A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
Trial testing whether subcutaneous mezagitamab maintains stable platelet counts in adults with immune thrombocytopenia compared to placebo.
12 Jun 2026 NCT06722235
● Recruiting Phase III Respiratory / COPD / Asthma
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
Intervention being tested: Filgotinib, a JAK1-selective inhibitor, is being evaluated for efficacy, safety, tolerability, and pharmacokinetics in paediatric and adolescent patients with ulcerative colitis…
12 Jun 2026 NCT06865417
● Recruiting Phase III Oncology
Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)
What is being tested: Belzutifan (MK-6482), a hypoxia-inducible factor (HIF-2α) inhibitor, is being evaluated in an extension study for patients with advanced solid tumors…
12 Jun 2026 NCT07405164
● Recruiting Phase III Cardiology / Cardiovascular
Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke
What is being tested: Sovateltide, a neuroprotective agent designed to protect brain tissue during acute ischaemic stroke and potentially promote neural repair in the…
12 Jun 2026 NCT05691244
● Recruiting Phase III Oncology
A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy
What is being tested: IDRX-42 (GSK6042981), a novel investigational drug, is being evaluated against sunitinib (standard comparator) in adults with gastrointestinal stromal tumors (GIST)…
12 Jun 2026 NCT07218926
● Recruiting Phase III Oncology
A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study
What is being tested: Continued treatment with Roche investigational medicinal products (IMPs), either as monotherapy or in combination with other agents or comparators, in…
12 Jun 2026 NCT05862285
active not recruiting Phase III Cardiology / Cardiovascular
A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.
Inclisiran injection reduces heart attacks, strokes, and cardiovascular deaths in high-risk patients without prior heart disease, compared to placebo.
12 Jun 2026 NCT05739383
● Recruiting Phase III Diabetes / Metabolic
Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity
MET097 injected once weekly helped adults with obesity or overweight lose weight over 64 weeks of treatment.
12 Jun 2026 NCT07311850
● Recruiting Phase III Oncology
An Extension Study for Patients Previously Enrolled in Studies With Pelabresib
What is being tested: Long-term safety and clinical benefit of pelabresib (a BET inhibitor) in patients with hematological and/or solid tumors, including evaluation of…
12 Jun 2026 NCT06401356
● Recruiting Phase III Rheumatology
A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants With Moderate to Severe Plaque Psoriasis
Trial testing deucravacitinib dosing, effectiveness and safety in children aged 4-17 with moderate-to-severe psoriasis over five years.
09 Jun 2026 NCT04772079
● Recruiting Phase III Oncology
A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Treatment being tested: Pirtobrutinib (LOXO-305), a novel BTK inhibitor, is being compared against ibrutinib (standard BTK inhibitor) in patients with chronic lymphocytic leukaemia/small lymphocytic…
09 Jun 2026 NCT05254743
active not recruiting Phase III Neurology
Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis
Fingolimod was safer and more effective than interferon beta-1a for reducing MS relapses in children.
08 Jun 2026 NCT01892722