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Trial Radar

1003 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

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Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

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active not recruiting Phase III Oncology
A Study of Subcutaneously Injected Epcoritamab Plus Oral Lenalidomide Tablets Compared to Intravenously (IV) Infused Rituximab Plus IV Infused Gemcitabine and IV Infused Oxaliplatin in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Trial comparing injected epcoritamab plus tablets (with or without lenalidomide) to intravenous chemotherapy for relapsed/refractory lymphoma.
08 Apr 2026 NCT06508658
active not recruiting Phase III Oncology
A Phase 3 Trial of Epcoritamab vs Investigator’s Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)
Epcoritamab (injected weekly then fortnightly) compared to standard chemotherapy for people with relapsed/refractory lymphoma ineligible for stem cell transplant.
08 Apr 2026 NCT04628494
● Recruiting Phase III Cardiology / Cardiovascular
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) is Recruiting • Phase III…
08 Apr 2026 NCT07517263
● Recruiting Phase III Oncology
Beamion LUNG-3: A Study to Test Whether Zongertinib Helps People With Surgically Removed, Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment
Beamion LUNG-3: A Study to Test Whether Zongertinib Helps People With Surgically Removed, Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment…
08 Apr 2026 NCT07195695
● Recruiting Phase III Oncology
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial…
08 Apr 2026 NCT06989112
● Recruiting Phase III Dermatology
A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis
A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than…
07 Apr 2026 NCT06461897
● Recruiting Phase III Diabetes / Metabolic
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight is Recruiting • Phase III…
07 Apr 2026 NCT07339423
● Recruiting Phase III Oncology
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer is Recruiting • Phase III…
07 Apr 2026 NCT05253651
● Recruiting Phase III Oncology
A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC) is Recruiting • Phase III • Oncology • NCT07164443. The…
07 Apr 2026 NCT07164443
● Recruiting Phase III Oncology
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer…
07 Apr 2026 NCT07062965
● Recruiting Phase III Oncology
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation…
07 Apr 2026 NCT05696626
● Recruiting Phase III Cardiology / Cardiovascular
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation is Recruiting • Phase III •…
07 Apr 2026 NCT06200207
● Recruiting Phase III Oncology
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer…
07 Apr 2026 NCT06875310
● Recruiting Phase III Oncology
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell…
07 Apr 2026 NCT06758401
● Recruiting Phase III Oncology
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors is Recruiting • Phase III • Oncology…
07 Apr 2026 NCT03067181
● Recruiting Phase III Oncology
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive…
07 Apr 2026 NCT07144280
● Recruiting Phase III Rheumatology
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines is Recruiting • Phase III…
06 Apr 2026 NCT06671496
active not recruiting Phase III Oncology
Efficacy and Safety of 177Lu-edotreotide PRRT in GEP-NET Patients
Efficacy and Safety of 177Lu-edotreotide PRRT in GEP-NET Patients is Active Not Recruiting • Phase III • Oncology • NCT03049189. Review the linked registry…
06 Apr 2026 NCT03049189
active not recruiting Phase III
A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Chronic Migraine in Adults
A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Chronic Migraine in Adults is Active Not Recruiting • Phase…
06 Apr 2026 NCT06047444
● Recruiting Phase III Dermatology
A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor
A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With…
06 Apr 2026 NCT06241118
● Recruiting Phase III Oncology
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer is Recruiting • Phase III • Oncology •…
06 Apr 2026 NCT07228832
● Recruiting Phase III Neurology
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson’s Disease
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson’s Disease is Recruiting • Phase III •…
06 Apr 2026 NCT07174310
● Recruiting Phase III Rheumatology
Crohn’s Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn’s Disease
Crohn’s Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn’s Disease is Recruiting • Phase III •…
06 Apr 2026 NCT06332534
● Recruiting Phase III Oncology
A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated…
06 Apr 2026 NCT04928846
● Recruiting Phase III
A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps
A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps…
03 Apr 2026 NCT06834347
active not recruiting Phase III Rare Diseases
A Study to Evaluate the Efficacy and Safety of Factor IX Gene Therapy With PF-06838435 in Adult Males With Moderately Severe to Severe Hemophilia B
A Study to Evaluate the Efficacy and Safety of Factor IX Gene Therapy With PF-06838435 in Adult Males With Moderately Severe to Severe Hemophilia…
03 Apr 2026 NCT03861273
● Recruiting Phase III
Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation
Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation is Recruiting •…
03 Apr 2026 NCT06465953
● Recruiting Phase III Oncology
Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician’s Choice New Hormonal Agents
Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician’s Choice New Hormonal Agents is Recruiting • Phase III • Oncology…
03 Apr 2026 NCT06120491
● Recruiting Phase III Oncology
Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.
Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i. is Recruiting • Phase III • Oncology • NCT06382948.…
03 Apr 2026 NCT06382948
● Recruiting Phase III Respiratory / COPD / Asthma
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer’s Disease
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer’s Disease is Recruiting • Phase III • Respiratory / COPD / Asthma • NCT07169578.…
03 Apr 2026 NCT07169578
● Recruiting Phase III Gastroenterology
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH is Recruiting • Phase III •…
03 Apr 2026 NCT06419374
● Recruiting Phase III Oncology
A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).
A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of…
03 Apr 2026 NCT06646276
● Recruiting Phase III Oncology
A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)
A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand…
03 Apr 2026 NCT06345729
● Recruiting Phase III Respiratory / COPD / Asthma
Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)
Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP) is Recruiting • Phase III • Respiratory / COPD / Asthma…
03 Apr 2026 NCT05722938
● Recruiting Phase III Respiratory / COPD / Asthma
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023) is Recruiting •…
03 Apr 2026 NCT06667700
● Recruiting Phase III Cardiology / Cardiovascular
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin is Recruiting • Phase III • Cardiology / Cardiovascular…
03 Apr 2026 NCT06677060
● Recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive…
03 Apr 2026 NCT06790693
● Recruiting Phase III Oncology
Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.
Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma. is Recruiting • Phase III • Oncology…
03 Apr 2026 NCT05727904
active not recruiting Phase III Dermatology
A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic Purpura
A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic Purpura is Active Not Recruiting • Phase III • Dermatology • NCT04683003. Review the…
02 Apr 2026 NCT04683003
● Recruiting Phase III Diabetes / Metabolic
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight is Recruiting • Phase III •…
02 Apr 2026 NCT07253285
● Recruiting Phase III Rheumatology
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK) is Recruiting • Phase III • Rheumatology • NCT07116967. Review the linked…
02 Apr 2026 NCT07116967
● Recruiting Phase III
The Efficacy and Safety of Rilzabrutinib in Patients Aged 10 to 65 Years With Sickle-cell Disease
The Efficacy and Safety of Rilzabrutinib in Patients Aged 10 to 65 Years With Sickle-cell Disease is Recruiting • Phase III • NCT06975865. Review…
02 Apr 2026 NCT06975865
active not recruiting Phase III
A Phase III Study to Evaluate the Efficacy and Safety of Benralizumab in Patients With Hypereosinophilic Syndrome (HES)
A Phase III Study to Evaluate the Efficacy and Safety of Benralizumab in Patients With Hypereosinophilic Syndrome (HES) is Active Not Recruiting • Phase…
02 Apr 2026 NCT04191304
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD) is Recruiting • Phase III • Respiratory…
02 Apr 2026 NCT05878769
● Recruiting Phase III Oncology
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012) is Recruiting • Phase III • Oncology • NCT06393374.…
02 Apr 2026 NCT06393374
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids) is Recruiting…
02 Apr 2026 NCT07107945
● Recruiting Phase III Cardiology / Cardiovascular
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin) is Recruiting • Phase III • Cardiology / Cardiovascular…
02 Apr 2026 NCT06531824
● Recruiting Phase III Respiratory / COPD / Asthma
A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast
A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast is…
02 Apr 2026 NCT06238622
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease is Recruiting • Phase III • Respiratory / COPD / Asthma •…
02 Apr 2026 NCT05595642
● Recruiting Phase III Respiratory / COPD / Asthma
MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma
MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma is Recruiting • Phase III • Respiratory / COPD / Asthma • NCT06097728.…
02 Apr 2026 NCT06097728