Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE)
Being tested: Long-term safety and efficacy of belimumab (a B-lymphocyte stimulator inhibitor) in adults with interstitial lung disease associated with systemic sclerosis and other…
09 Sep 2026 NCT06716606
● Recruiting Cardiology / Cardiovascular
Establishing the Incidence of Tako-tsubo Cardiomyopathy in Scotland
Study Focus: This research establishes the true incidence and epidemiology of Takotsubo cardiomyopathy (stress-induced cardiomyopathy) across Scotland, a condition that mimics acute myocardial infarction…
09 Sep 2026 NCT03299569
● Recruiting Cardiology / Cardiovascular
Barts Sex-CAD Database – Sex Hormones and Inflammatory Status in Coronary Artery Disease
What is being tested: The relationship between sex hormones, inflammatory markers, and the development/progression of coronary artery disease (CAD) in women, addressing a significant…
09 Sep 2026 NCT06327984
● Recruiting Phase III Cardiology / Cardiovascular
Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies
What is being tested: IgPro20 (immunoglobulin replacement therapy) efficacy, safety, and pharmacokinetics in adults with secondary immune deficiencies resulting from B-cell targeting CAR T-cell…
09 Sep 2026 NCT07648264
● Recruiting Phase III Oncology
A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)
What is being tested: Precemtabart tocentecan (Precem-TcT), administered with or without bevacizumab, is being compared against the standard treatment of trifluridine/tipiracil plus bevacizumab in…
09 Sep 2026 NCT07549412
● Recruiting Oncology
Observational Study of Acalabrutinib in Patients With Chronic Lymphocytic Leukaemia in the United Kingdom
What is being tested: Real-world clinical outcomes and patient characteristics of acalabrutinib (a Bruton tyrosine kinase inhibitor) in UK patients with chronic lymphocytic leukaemia…
09 Sep 2026 NCT05557695
● Recruiting Oncology
PRostate Cancer Enhanced Diagnosis by Calibration Technology
What is being tested: The CARE® Phantom system enables quantitative measurement of apparent diffusion coefficient (ADC) values in prostate tissue during multi-parametric MRI (mpMRI)…
09 Sep 2026 NCT06607783
● Recruiting Oncology
Anatomical Landmarks for Chest Wall Perforators Used for Partial Breast Reconstruction
What is being tested: Identification and mapping of chest wall perforator vessels in relation to anatomical landmarks to guide surgical planning for partial breast…
09 Sep 2026 NCT07006662
● Recruiting Phase III Oncology
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
What is being tested: Sonesitatug vedotin (an antibody-drug conjugate targeting Claudin18.2) combined with capecitabine, with or without rilvegostomig (an ADAM10 inhibitor), as first-line treatment…
09 Sep 2026 NCT07431281
active not recruiting
BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)
Study tracking disease progression and lumasiran treatment outcomes in primary hyperoxaluria type 1 patients over time.
08 Sep 2026 NCT04982393
active not recruiting Phase I Diabetes / Metabolic
To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Phase I trial testing inavolisib alone and combined with standard breast cancer treatments in patients with PIK3CA-mutant tumours.
08 Sep 2026 NCT03006172
● Recruiting Phase II Dermatology
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)
Brenipatide injections tested against placebo in patients with constipation-type irritable bowel syndrome over 35 weeks for safety and effectiveness.
08 Sep 2026 NCT07545772
● Recruiting Oncology
EORTC Metastatic Breast Cancer Module Development
What is being tested: Development of a specialised Health-Related Quality of Life (HRQOL) measurement module specifically designed for metastatic breast cancer patients, addressing the…
08 Sep 2026 NCT07806266
● Recruiting Phase I Neurology
SIZOMUS Safety of Ixazomib Targeting Plasma Cells in Multiple Sclerosis
What is being tested: Ixazomib (NINLARO), a proteasome inhibitor licensed for multiple myeloma, is being investigated as a novel therapeutic agent to target plasma…
08 Sep 2026 NCT03783416
● Recruiting Phase III Respiratory / COPD / Asthma
A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease
What is being tested: Belimumab, a monoclonal antibody targeting B-lymphocyte stimulator (BLyS), is being evaluated for its efficacy and safety in treating interstitial lung…
08 Sep 2026 NCT06572384
● Recruiting Cardiology / Cardiovascular
Diagnosing Variable Primary Aldosteronism.
What is being tested: The study investigates whether patients with Primary Aldosteronism exhibit cyclical or exaggerated diurnal (daily) variations in aldosterone production, potentially identifying…
08 Sep 2026 NCT05765786
● Recruiting Cardiology / Cardiovascular
Cerebral Protection in Aortic Arch Surgery
What is being tested: Cerebral protection strategies during aortic arch repair surgery to reduce detrimental neurological complications (stroke and neuropsychological injury) that currently occur…
08 Sep 2026 NCT04966247
● Recruiting Women's Health
Effectiveness of Nutritional Resources for Milk Donors
Trial tests whether nutritional guidance for milk donors increases beneficial fatty acids in donated breast milk.
04 Sep 2026 NCT07042009
active not recruiting Phase III Oncology
Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC
Adding talazoparib to enzalutamide improves outcomes in men with metastatic prostate cancer and DNA repair gene mutations.
04 Sep 2026 NCT04821622
active not recruiting Respiratory / COPD / Asthma
Is the Vaginal Microbiome and Metabolome Associated With Spontaneous Preterm Birth (sPTB) in Multiple Pregnancies?
Study investigates whether vaginal bacteria in twin pregnancies are linked to early delivery to identify potential prevention treatments.
04 Sep 2026 NCT06053697
active not recruiting Phase III
A Phase 3 Study to Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and Rituximab Compared to Placebo Plus Lenalidomide and Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma or Marginal Zone Lymphoma.
Adding tafasitamab to standard lymphoma treatment improves outcomes in patients with relapsed or refractory follicular or marginal zone lymphoma.
04 Sep 2026 NCT04680052
● Recruiting Phase III
Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial
Depemokimab added to standard care reduced flares in adults with uncontrolled hypereosinophilic syndrome over 52 weeks.
04 Sep 2026 NCT05334368
● Recruiting Phase III
A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A
Study comparing NXT007 with emicizumab for preventing bleeding in hemophilia A patients aged 12 and over.
04 Sep 2026 NCT07416604
● Recruiting
Post-Market Clinical Follow-up (PMCF) Study of the Pitch-Patch for the Augmentation or Reinforcement of the Rotator Cuff
Study tracking long-term safety and effectiveness of Pitch-Patch, a synthetic reinforcement patch for rotator cuff tear repair, in 37 patients.
04 Sep 2026 NCT05906004
● Recruiting Cardiology / Cardiovascular
Real World European Investigation of Safety and Clinical Efficacy of the EVOQUE System (TRISCEND III EU)
What is being tested: The Edwards EVOQUE system is undergoing real-world safety and clinical efficacy evaluation across multiple European centres in a prospective, single-arm…
04 Sep 2026 NCT06569602
● Recruiting Phase III Oncology
Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer
What is being tested: This phase 3 trial evaluates whether lower doses of Androgen Receptor Pathway Inhibitors (ARPIs) can achieve equivalent clinical effectiveness compared…
04 Sep 2026 NCT07751133
● Recruiting Phase I Oncology
Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
ORIC-114 is being tested as a novel therapeutic agent either alone or combined with chemotherapy in patients with advanced solid tumors carrying EGFR or…
04 Sep 2026 NCT05315700
active not recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy
Adding immunotherapy to standard HER2 treatment reduces breast cancer recurrence risk in patients with residual disease after pre-surgery therapy.
03 Sep 2026 NCT04873362
active not recruiting Phase III Oncology
A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma
Trial testing combination immunotherapy plus targeted drugs for untreated advanced melanoma with BRAF mutations.
03 Sep 2026 NCT04657991
active not recruiting Phase II Oncology
Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01
Trial comparing two immunotherapy combinations with chemotherapy for advanced head and neck cancer, regardless of PD-L1 status.
03 Sep 2026 NCT06727565
● Recruiting Phase II Oncology
Irinotecan-ChemoSeed in Surgically Resectable Glioblastoma
What is being tested: Irinotecan-ChemoSeed, a locally-delivered chemotherapy implant, is being evaluated for safety, tolerability, and maximum tolerated dose (MTD) in patients undergoing surgical…
03 Sep 2026 NCT07356973
active not recruiting Phase I
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RG6496 in Huntington’s Disease
RG6496 is being tested in Huntington's disease gene carriers to assess its safety, tolerability, and how the body processes it.
02 Sep 2026 NCT07246941
active not recruiting
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy
Study tracking heart disease progression in children with MYBPC3 gene mutations to understand symptoms, treatments, and quality of life.
02 Sep 2026 NCT05112237
● Recruiting Phase III
A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia
A trial testing a new drug called atumelnant in adults with a genetic condition affecting the adrenal glands to check if it works, is…
02 Sep 2026 NCT07144163
active not recruiting Phase III Oncology
Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Adding quemliclustat to standard chemotherapy did not improve survival in advanced pancreatic cancer compared to chemotherapy alone.
02 Sep 2026 NCT06608927
active not recruiting Phase III
SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM
Trial comparing subcutaneous versus intravenous isatuximab combined with pomalidomide and dexamethasone in relapsed multiple myeloma.
02 Sep 2026 NCT05405166
● Recruiting Gastroenterology
Vision Baby : The Measurement of Vital Signs in Neonates by Lifelight® Software in Comparison to the Standard of Care
Vision Baby Study Summary Lifelight® software uses facial video to measure vital signs in newborns, compared against standard monitoring equipment.
02 Sep 2026 NCT07799870
● Recruiting Phase III Oncology
A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer
What is being tested: BNT324, a novel therapeutic agent, is being evaluated against docetaxel (standard chemotherapy) combined with corticosteroids in patients with metastatic castration-resistant…
02 Sep 2026 NCT07365995
● Recruiting Phase IV Respiratory / COPD / Asthma
A Randomized Controlled Trial Comparing Percutaneous CT-Guided Biopsy and Shape-Sensing Robotic-Assisted Bronchoscopy
What is being tested: The ENCOMPASS study compares diagnostic accuracy and safety outcomes between CT-guided percutaneous lung biopsy and shape-sensing robotic-assisted bronchoscopy with cone-beam…
02 Sep 2026 NCT07761351
● Recruiting Phase III Cardiology / Cardiovascular
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
What is being tested: IKT-001, a novel therapeutic agent, is being evaluated for efficacy and safety in treating WHO Group 1 pulmonary arterial hypertension…
02 Sep 2026 NCT07365332
● Recruiting Phase III Oncology
Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML
What is being tested: Revumenib (a menin inhibitor) combined with azacitidine and venetoclax in patients with newly diagnosed acute myeloid leukaemia (AML) harbouring NPM1…
02 Sep 2026 NCT06652438
● Recruiting
Influence of Timing of Implant Placement on Early Healing Molecular Events
Immediate dental implant placement may trigger different healing responses compared to delayed placement, based on inflammatory and bone-forming markers.
01 Sep 2026 NCT06276335
active not recruiting Phase II Oncology
A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)
Avelumab combined with other cancer drugs was tested as maintenance therapy in advanced bladder cancer to assess safety and effectiveness.
01 Sep 2026 NCT05327530
active not recruiting Phase III Oncology
A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers
Testing whether zanidatamab combined with chemotherapy (with or without an immunotherapy drug) works better than standard trastuzumab treatment in advanced stomach and gullet cancers.
01 Sep 2026 NCT05152147
active not recruiting Mental Health / Psychiatry
Correcting Myopia Among Secondary School Children to Increase Academic High School Attendance Rates in Rural Communities
Free glasses with teacher support increases academic high school attendance among short-sighted rural Chinese secondary school students.
01 Sep 2026 NCT04077086
● Recruiting Phase I Neurology
A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson’s Disease
Drug being tested: LY3962681, a novel investigational compound undergoing evaluation for safety, tolerability, and pharmacokinetic/pharmacodynamic properties in both healthy volunteers and Parkinson's disease patients…
01 Sep 2026 NCT06565195
● Recruiting Neurology
Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants Earlier Within Advanced Parkinson Disease
What is being tested: Foslevodopa/foscarbidopa (a continuous subcutaneous infusion therapy) is being evaluated for its effects on quality of life outcomes in adults with…
01 Sep 2026 NCT07227896
● Recruiting Rare Diseases
Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study
What is being tested: This is a natural history study tracking disease progression in Friedreich ataxia patients over time across multiple international centers, rather…
01 Sep 2026 NCT06016946
● Recruiting Phase I Respiratory / COPD / Asthma
To Identify if a COPD Self-management App Can Safety and Appropriately Identify When Patients Are Not on the Best Medication Plan for Their COPD Symptoms and Support Their COPD Management.
What is being tested: A COPD self-management app designed to safely and accurately identify when patients are not receiving optimal inhaled therapy for their…
01 Sep 2026 NCT07797985
● Recruiting Phase III Cardiology / Cardiovascular
Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE
What is being tested: Once-daily oral deucrictibant extended-release tablet as a preventative treatment to reduce angioedema attack frequency in patients with hereditary angioedema (HAE),…
01 Sep 2026 NCT06679881