Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Cardiology / Cardiovascular
NAIF 2.0 – COGNIFY
What is being tested: This observational study investigates whether intracranial dural arteriovenous fistulae (abnormal arterial-venous connections in the brain's protective membrane) impair the glymphatic…
17 Sep 2026 NCT07824297
● Recruiting Phase I
A Study to Evaluate ALN-4915 in Adult Healthy Volunteers
A study testing a new drug called ALN-4915 in healthy adults to check if it's safe and how the body processes it.
16 Sep 2026 NCT07535606
active not recruiting Phase I Oncology
NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer
NG-350A combined with standard chemoradiotherapy improves outcomes in high-risk locally advanced rectal cancer patients.
16 Sep 2026 NCT06459869
● Recruiting Phase I
A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington’s Disease
A trial testing whether a new drug (ALN-HTT02) is safe and effective in adults with Huntington's disease.
16 Sep 2026 NCT06585449
active not recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer
Trial comparing divarasib to sotorasib/adagrasib for treating advanced lung cancer with KRAS G12C mutation in previously treated patients.
16 Sep 2026 NCT06497556
● Recruiting Phase II Respiratory / COPD / Asthma
Phase 2b Study of a Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Protein Vaccine Candidate in Adults 60 Years of Age and Older
A Phase 2b trial testing a single-dose vaccine against RSV and metapneumovirus in 8,000 adults aged 60+, measuring effectiveness, safety, and immune response.
16 Sep 2026 NCT07810010
● Recruiting Oncology
Feasibility Study to Evaluate the Use of Patient Reported Complications After Digital Consent
What is being tested: This feasibility study investigates whether patients can reliably report post-procedural complications directly through a digital consent platform, evaluating both the…
16 Sep 2026 NCT06351865
● Recruiting Respiratory / COPD / Asthma
PANDA-ASOCT: Paediatric Anterior Uveitis Detection With Automated Image Analysis Using ASOCT
What is being tested: Automated image analysis using Anterior Segment Optical Coherence Tomography (ASOCT) to detect paediatric anterior uveitis, aiming to improve diagnostic accuracy…
16 Sep 2026 NCT07813598
● Recruiting Phase II Oncology
A Study to Evaluate the Efficacy of VVD-133214 in Combination With Pembrolizumab Compared With Pembrolizumab Alone in Participants With Advanced Cancer of the Colon or Rectum
Treatment being tested: VVD-133214 (a novel therapeutic agent) combined with pembrolizumab (an immune checkpoint inhibitor) versus pembrolizumab monotherapy in patients with advanced colorectal cancer,…
16 Sep 2026 NCT07811193
● Recruiting Oncology
Magseed Pro(R)/ Sentimag(R) Gen3
What is being tested: The Magseed Pro®/Sentimag® Gen3 system—a magnetic marker and detection device combination—is being evaluated for safely and effectively marking suspicious or…
16 Sep 2026 NCT05142787
● Recruiting Phase I Oncology
A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)
What is being tested: Autologous CAR T cell therapy engineered to target CD19 antigen in pediatric patients with relapsed or refractory B-cell acute lymphoblastic…
16 Sep 2026 NCT06173518
active not recruiting Phase I / Phase II Neurology
Brainshuttle AD: A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Participants With Prodromal or Mild to Moderate Alzheimer’s Disease
Study testing increasing doses of RO7126209 infusions to assess safety and effectiveness in early Alzheimer's disease patients with amyloid buildup.
14 Sep 2026 NCT04639050
● Recruiting Phase III Mental Health / Psychiatry
Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia
KarXT may help prevent relapse in schizophrenia patients already responding to treatment.
14 Sep 2026 NCT07686263
● Recruiting Phase III Oncology
A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
Trial comparing subcutaneous versus intravenous tislelizumab plus chemotherapy for advanced gastric cancer in 351 patients.
14 Sep 2026 NCT07043400
active not recruiting
Long-term Follow-up of Participants With Cerebral Adrenoleukodystrophy Who Were Treated With Lenti-D Drug Product
Long-term safety and effectiveness follow-up study of gene therapy (eli-cel) in patients with cerebral adrenoleukodystrophy over 15 years.
14 Sep 2026 NCT02698579
● Recruiting Respiratory / COPD / Asthma
A Randomised Feasibility Study of CPAP in Large Airway Collapse
What is being tested: A feasibility study evaluating the effectiveness and safety of continuous positive airway pressure (CPAP) therapy as a non-invasive treatment for…
14 Sep 2026 NCT07504926
● Recruiting Cardiology / Cardiovascular
Non-invasive Coronary Thrombus Imaging to Define These Cause of Acute Myocardial Infarction
What is being tested: Non-invasive imaging techniques to identify coronary thrombus (blood clots) as the underlying cause of acute myocardial infarction, addressing the limitation…
14 Sep 2026 NCT06113510
● Recruiting Oncology
Computerized Registry of Patients With Venous Thromboembolism (RIETE)
What is being tested: RIETE is a computerized registry prospectively collecting extensive clinical data on consecutive patients diagnosed with venous thromboembolism (VTE), including deep…
14 Sep 2026 NCT02832245
active not recruiting Phase II Gastroenterology
Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
A new drug called tilpisertib fosmecarbil tested against placebo in patients with moderate-to-severe ulcerative colitis to see if it improves symptoms by week 12.
11 Sep 2026 NCT06029972
● Recruiting Phase I Gastroenterology
Human Mass Balance Study of [14C] Ontunisertib in Healthy Volunteers
Study tracking how the body absorbs, processes and eliminates a single dose of ontunisertib using radioactive labelling in healthy men.
11 Sep 2026 NCT07672574
active not recruiting Phase II
A Study of Ianalumab (VAY736) in Patients With Primary Immune Thrombocytopenia (ITP) Previously Treated With at Least Two Lines of Therapies
Ianalumab is tested in adults with hard-to-treat immune thrombocytopenia who've failed previous treatments.
11 Sep 2026 NCT05885555
● Recruiting Oncology
International Prospective REgistry on Pre-pectorAl Breast REconstruction
What is being tested: Surgical outcomes, aesthetic results, and oncological safety of pre-pectoral breast implant reconstruction following mastectomy for breast cancer across multiple international…
11 Sep 2026 NCT05817175
● Recruiting Phase II Gastroenterology
A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial).
What is being tested: A combination therapy using human albumin and enoxaparin (low-molecular-weight heparin) in hospitalised patients with decompensated cirrhosis to assess safety and…
11 Sep 2026 NCT05895136
● Recruiting Cardiology / Cardiovascular
Mechanisms of Atrial Pathoelectrophysiology in HCM
What is being tested: This research investigates the underlying electrophysiological mechanisms responsible for the increased incidence and treatment resistance of atrial fibrillation in patients…
11 Sep 2026 NCT07454135
● Recruiting Cardiology / Cardiovascular
The Origin and Role of Thromboembolism in the Pathogenesis of Ischaemic Stroke
What is being tested: This trial investigates the origin of thrombi causing ischaemic stroke and examines whether thrombosis itself is the primary pathogenic mechanism,…
11 Sep 2026 NCT05636748
● Recruiting Oncology
Breath Research Narrow Validation for Gastrointestinal Cancer Detection
What is being tested: A non-invasive breath test designed to detect volatile organic compounds (VOCs) as biomarkers for early identification of gastrointestinal cancers (oesophageal,…
11 Sep 2026 NCT07714538
● Recruiting Neurology
Natural History of Type 1 Interferonopathies: Insights From a European Cohort
European study tracking type 1 interferonopathy progression in children and adults to improve diagnosis, prognosis, and personalise treatment options.
10 Sep 2026 NCT07040774
● Recruiting Diabetes / Metabolic
Effects of Quercetin on Cardiometabolic Outcomes
Quercetin supplement compared to placebo in randomized trial to test whether it improves heart disease and diabetes risk factors.
10 Sep 2026 NCT06230861
active not recruiting Cardiology / Cardiovascular
Early Valve Replacement Guided by Biomarkers of LV Decompensation in Asymptomatic Patients With Severe AS
Early aortic valve surgery guided by heart scarring markers may improve outcomes in asymptomatic patients with severe stenosis.
10 Sep 2026 NCT03094143
active not recruiting Infectious Disease
Accelerometry and Rehabilitation After Knee Replacement Study (ARK)
Wearable sensors with remote monitoring may improve exercise compliance and outcomes after knee replacement compared to standard physiotherapy.
10 Sep 2026 NCT05412940
● Recruiting Phase II
Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
A study testing whether a new drug called Imeroprubart helps adults with chronic nerve inflammation and weakness.
10 Sep 2026 NCT07032662
active not recruiting
Versius Paediatrics Study
Testing whether Versius robotic surgery is safe and effective for urological procedures in children, starting with three procedures then expanding if safe.
10 Sep 2026 NCT06539442
active not recruiting
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)
Older adults with leaky mitral valves randomly received either catheter-based or surgical repair to compare which approach works better.
10 Sep 2026 NCT05051033
● Recruiting Phase III Respiratory / COPD / Asthma
A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer’s Disease
Treatment being tested: Trontinemab, a monoclonal antibody targeting Alzheimer's disease pathology, is being evaluated in cognitively unimpaired individuals with biomarker evidence of AD pathology…
10 Sep 2026 NCT07717411
● Recruiting Neurology
Digital App for Speech & Health Monitoring
What is being tested: A smartphone application that uses digital technology to record and analyse speech patterns in patients with neurodegenerative conditions (dementia, MND,…
10 Sep 2026 NCT06450418
● Recruiting Phase II Respiratory / COPD / Asthma
Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD
Treatment Being Tested: Two different oral doses of vapendavir (an investigational antiviral) versus placebo in COPD patients with rhinovirus (RV) infection, aimed at reducing…
10 Sep 2026 NCT07610395
● Recruiting Phase II Respiratory / COPD / Asthma
A Study to Investigate the Efficacy and Safety of SC0032, a Magnesium Salt Oral Spray, in Adults With Refractory or Unexplained Chronic Cough
What is being tested: SC0032, a magnesium salt oral spray formulation, is being evaluated in a randomized placebo-controlled trial to assess its efficacy and…
10 Sep 2026 NCT07690059
● Recruiting Respiratory / COPD / Asthma
Perpetual Observational Study – Ventilator Associated Pneumonia
What is being tested: This perpetual observational study is monitoring the epidemiology, microbiology, and outcomes of ventilator-associated pneumonia (VAP) in ICU patients requiring mechanical…
10 Sep 2026 NCT05719259
● Recruiting Phase II Respiratory / COPD / Asthma
Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)
What is being tested: BTI-203 evaluates rhu-pGSN (recombinant human plasma gelsolin), an anti-inflammatory agent, combined with standard care versus placebo in a randomized, double-blind…
10 Sep 2026 NCT05947955
● Recruiting Phase III Diabetes / Metabolic
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
What is being tested: AZD6234 as an adjunctive treatment to incretin-based therapies, with efficacy measured by percentage body weight change from baseline over 68…
10 Sep 2026 NCT07776509
● Recruiting Phase III Cardiology / Cardiovascular
Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)
What is being tested: Intranasal cenegermin (a recombinant human nerve growth factor) versus vehicle control to assess efficacy and safety in treating non-arteritic anterior…
10 Sep 2026 NCT07453888
● Recruiting Cardiology / Cardiovascular
Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation
What is being tested: Novel echocardiographic technologies and methods to improve the accuracy of measuring left ventricular filling pressure in patients with concurrent heart…
10 Sep 2026 NCT07436299
● Recruiting Phase I Oncology
CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors
CR-001 monotherapy is being evaluated for safety, tolerability, and dose optimization (MTD/RP2D) in adults with locally advanced or metastatic solid tumors, representing early-stage clinical…
10 Sep 2026 NCT07335497
active not recruiting Phase III Diabetes / Metabolic
A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight
Semaglutide weekly injections help children and teenagers lose weight better than placebo, alongside lifestyle support.
09 Sep 2026 NCT05726227
● Recruiting
Influence of Gut Microbiome in Gallstone Disease
Study examining whether gut bacteria composition relates to gallstone complications and changes after gallbladder removal surgery.
09 Sep 2026 NCT05732480
active not recruiting Rheumatology
Development of a New Patient Reported Outcome Measure (PROM) to Assess Patient’s Emotional Wellbeing, and Perceptions of Total Knee Replacement Surgery for the Treatment of Knee Arthritis
Researchers created a new questionnaire to measure how knee replacement patients feel emotionally and perceive their surgery outcomes.
09 Sep 2026 NCT06585267
● Recruiting Respiratory / COPD / Asthma
A Long-term Observational Study Evaluating the Presentation and Management of Acute Respiratory Tract Infections in Primary Care Across Europe
Long-term European study examining how respiratory infections present and are managed in GP surgeries.
09 Sep 2026 NCT06282718
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
What is being tested: Elecoglipron, a novel therapeutic agent, is being evaluated against placebo for its effects on cardiovascular outcomes in patients with HFpEF…
09 Sep 2026 NCT07761117
● Recruiting Oncology
Chemo Brain Prehab Project
What is being tested: A prehabilitation (pre-treatment) intervention designed to prevent or mitigate chemotherapy-induced cognitive impairment ("chemo brain") in colorectal cancer patients receiving fluorouracil,…
09 Sep 2026 NCT07341217
● Recruiting Phase III Diabetes / Metabolic
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
What is being tested: Elecoglipron (a novel therapeutic agent) versus placebo in adults with chronic kidney disease, with or without type 2 diabetes, all…
09 Sep 2026 NCT07753993