Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase I Oncology
A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer
Investigational Agent: GDC-1261 is being tested for the first time in prostate cancer patients to assess its safety profile, how the body processes it…
11 Aug 2026 NCT07567846
● Recruiting Neurology
Lived Experience Narratives in Dementia
What is being tested: The LEND research programme is investigating how narrative-based interventions can benefit people living with dementia across multiple work packages, with…
11 Aug 2026 NCT07757178
● Recruiting Neurology
Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)
What is being tested: The study evaluates the safety of diroximel fumarate (DRF/Vumerity) exposure during pregnancy by estimating the risk of major congenital malformations…
11 Aug 2026 NCT05658497
● Recruiting Phase I Respiratory / COPD / Asthma
A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)
TSRA-196 is being tested as a potential therapeutic intervention in adults with PiZZ alpha-1 antitrypsin deficiency (AATD), a serious genetic disorder causing progressive lung…
11 Aug 2026 NCT07227207
● Recruiting Gastroenterology
International Wilson’s Disease Patient Registry (iWilson Registry)
What is being tested: The iWilson Registry is a longitudinal, observational study collecting standardised clinical data from Wilson's disease patients attending routine clinic visits…
11 Aug 2026 NCT05239858
● Recruiting Rheumatology
PIBD-SETQuality: the Inception Cohort and Safety Registry
What is being tested: Effectiveness and safety of current treatment strategies for pediatric-onset inflammatory bowel disease (IBD) in routine clinical practice, with correlation to…
11 Aug 2026 NCT03571373
● Recruiting Phase II Cardiology / Cardiovascular
A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease
What is being tested: PRX-102, a novel therapeutic agent, is being evaluated for safety and efficacy in the paediatric population (children and adolescents) with…
11 Aug 2026 NCT06328608
● Recruiting Phase I Oncology
Investigating the Combination of Bexmarilimab and Nivolumab in Solid Tumours, Melanoma and NSCLC
What is being tested: A combination of bexmarilimab (a CSF-1R inhibitor) with nivolumab (a PD-1 checkpoint inhibitor) in patients with advanced melanoma and non-small…
11 Aug 2026 NCT07718243
● Recruiting Phase I Oncology
A Study of MGC026 in Participants With Advanced Solid Tumors
What is being tested: MGC026, a novel therapeutic agent, is being evaluated for safety, tolerability, pharmacokinetics, immunogenicity, and antitumor activity in patients with advanced…
11 Aug 2026 NCT06242470
● Recruiting Phase I Oncology
Allogeneic T Cells Expressing T Cell Receptor-KDEL and the Chimeric Antigen Receptor CAT19 for the Treatment of Advanced CD19+ Malignancies
What is being tested: KCAT19 evaluates allogeneic T cells engineered with dual receptors (TCR-KDEL and CAR-targeting CD19) as a novel immunotherapy for advanced, treatment-resistant…
11 Aug 2026 NCT05391490
● Recruiting Phase III Oncology
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)
Trial testing whether mRNA vaccine plus immunotherapy reduces lung cancer recurrence after surgery in high-risk patients.
10 Aug 2026 NCT07513376
● Recruiting Phase II
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy
Trial testing ARGX-119 injections in children aged 5-17 with spinal muscular atrophy alongside standard treatment.
10 Aug 2026 NCT07287982
● Recruiting Phase III Gastroenterology
A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for Induction and Maintenance Therapy in Children With Moderately to Severely Active Crohn’s Disease
Trial testing a new drug (Afimkibart) for treating moderate-to-severe Crohn's disease in children.
10 Aug 2026 NCT07298421
active not recruiting Phase III Diabetes / Metabolic
A Trial of Setmelanotide in Acquired Hypothalamic Obesity
Setmelanotide daily injections tested for weight loss and quality of life improvement in acquired hypothalamic obesity patients aged 4+ years.
10 Aug 2026 NCT05774756
active not recruiting Phase II Gastroenterology
A Gene Delivery Study to Evaluate the Safety and Expression of Delandistrogene Moxeparvovec in Participants Under the Age of Four With Duchenne Muscular Dystrophy (DMD)
Gene therapy trial testing safety and effectiveness of a new treatment for very young children with Duchenne muscular dystrophy over five years.
10 Aug 2026 NCT06128564
● Recruiting Cardiology / Cardiovascular
Improving Sleep and Learning in Rehabilitation After Stroke, Part 2
Digital cognitive behavioural therapy improves sleep in stroke survivors and may enhance motor learning recovery compared to standard care.
10 Aug 2026 NCT05511285
● Recruiting Phase III Rheumatology
A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic Arthritis
Baricitinib safety and effectiveness for children aged 1-17 with juvenile idiopathic arthritis.
07 Aug 2026 NCT03773965
● Recruiting
3D Animation and Models to Aid Management of Fetal CDH
3D models of unborn babies with lung defects help parents understand the condition and surgeons plan birth operations.
07 Aug 2026 NCT03750266
active not recruiting Phase III Infectious Disease
A Study of the Efficacy and Safety of Risankizumab in Participants With Crohn’s Disease
Risankizumab maintains remission in moderate-to-severe Crohn's disease; studies examine dosing schedules, long-term safety, and injection device preferences.
07 Aug 2026 NCT03105102
active not recruiting Phase II Gastroenterology
A Study to Evaluate the Long-Term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn’s Disease
A trial testing two maintenance doses of TEV-48574 injection to keep moderate-to-severe ulcerative colitis or Crohn's disease under control long-term.
07 Aug 2026 NCT05668013
● Recruiting Phase II Oncology
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
Treatment being tested: Zanzalintinib (a novel investigational agent) is being compared directly against everolimus (current standard of care) in patients with advanced neuroendocrine tumors…
07 Aug 2026 NCT06943755
● Recruiting Phase III
A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia
INCA033989 is tested against standard treatment in patients with essential thrombocythemia and CALR mutations who've had previous cytoreductive therapy.
06 Aug 2026 NCT07623200
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis
Trial testing whether nerandomilast tablet improves symptoms and slows disease in systemic sclerosis patients over one to four years.
06 Aug 2026 NCT07497087
● Recruiting Phase II
A Study of Brenipatide in Participants With Opioid Use Disorder
Testing whether brenipatide added to buprenorphine treatment improves outcomes for people with opioid addiction compared to placebo.
06 Aug 2026 NCT07420283
active not recruiting Phase III Diabetes / Metabolic
Weight Loss in People Living With Overweight or Obesity Following Treatment With Cagrilintide
Experimental weight-loss injection cagrilintide tested against placebo in overweight or obese adults over 18 months.
06 Aug 2026 NCT07220642
● Recruiting Phase III
A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A
NXT007 compared to standard Factor VIII treatment for preventing bleeding in people with moderate-to-severe hemophilia A.
06 Aug 2026 NCT07416526
● Recruiting Oncology
AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.
Being tested: AURORA is evaluating molecular aberrations in metastatic breast cancer through comprehensive genomic profiling to identify genetic and molecular drivers of disease progression…
06 Aug 2026 NCT02102165
● Recruiting Phase II Gastroenterology
Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions
What is being tested: AHB-137 injection is being evaluated as an add-on therapy to existing Nucleos(t)ide Analogue treatment in a phase 2 randomised controlled…
06 Aug 2026 NCT07654283
● Recruiting Respiratory / COPD / Asthma
Balance Training Following Pulmonary Rehabilitation on Balance in People With Chronic Obstructive Pulmonary Disease (COPD)
What is being tested: A co-designed balance training programme called Sport4Steadiness (S4S) delivered following pulmonary rehabilitation to assess its acceptability and feasibility in people…
06 Aug 2026 NCT07750821
● Recruiting Respiratory / COPD / Asthma
Less Invasive Surfactant Administration in Late Preterm or Early Term Born Infants
What is being tested: Less invasive surfactant administration (LISA) delivered via a thin catheter during high-flow nasal cannula therapy, compared to standard care, to…
06 Aug 2026 NCT06421506
● Recruiting Phase II Cardiology / Cardiovascular
A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma
What is being tested: Cemsidomide (a cereblon E3 ligase modulator) combined with dexamethasone in patients with relapsed/refractory multiple myeloma, evaluating its antimyeloma activity, safety,…
06 Aug 2026 NCT07284758
● Recruiting Phase III Oncology
BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease
What is being tested: BGB-43395 (a novel protein degrader) combined with letrozole is being compared against standard CDK4/6 inhibitors plus letrozole as first-line treatment…
06 Aug 2026 NCT07492641
● Recruiting Phase III
A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib
Trial testing whether adding elritercept to ruxolitinib improves anaemia and symptoms in myelofibrosis patients versus placebo.
05 Aug 2026 NCT07623161
● Recruiting Phase II
Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)
Early-stage trial testing whether a new injection drug is safe and well-tolerated in adults with sickle cell disease over 64 weeks.
05 Aug 2026 NCT07224360
active not recruiting Mental Health / Psychiatry
12-week Magnesium Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being
Magnesium supplementation for 12 weeks may improve hot flushes, sleep, mood, and thinking in perimenopausal women.
05 Aug 2026 NCT07235878
● Recruiting Infectious Disease
Teamwork for Resilient Staff and Safe Care in ICU
Study observing how ICU staff collaborate daily, identifying teamwork strengths, challenges, and pandemic-related changes through shadowing and interviews.
05 Aug 2026 NCT06389773
active not recruiting Phase III
A Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)
Aficamten improves symptoms and exercise ability in non-obstructive hypertrophic cardiomyopathy compared to placebo.
05 Aug 2026 NCT06081894
● Recruiting Phase I / Phase II Rare Diseases
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations
Gene therapy trial testing safety and effectiveness of DB-OTO for hearing loss caused by otoferlin gene mutations in children and adults.
05 Aug 2026 NCT05788536
active not recruiting Phase II Oncology
Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study
TAPISTRY Trial Summary Study tests tailored cancer drugs matched to individual tumour genetic mutations across multiple cancer types.
05 Aug 2026 NCT04589845
● Recruiting
Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears
REGENETEN implant may help patients return to daily activities faster than standard repair for partial rotator cuff tears.
05 Aug 2026 NCT05444465
● Recruiting
A Long-Term Observational Study of Patients With Fucosidosis
Study tracking how fucosidosis develops over time to inform future treatments, with no experimental intervention given.
05 Aug 2026 NCT07615400
● Recruiting Oncology
HER2+ CNS Surveillance
What is being tested: The feasibility of implementing regular brain MRI surveillance (baseline plus two six-monthly scans) versus no surveillance in patients with metastatic…
05 Aug 2026 NCT07748598
● Recruiting Phase IV Rare Diseases
Real-World Effectiveness and Safety of Pegcetacoplan in Patients With C3G or IC-MPG: A Multi-Country Study
What is being tested: Pegcetacoplan (a complement C3 inhibitor) effectiveness and safety in real-world clinical practice for patients with C3 glomerulopathy (C3G) and immune…
05 Aug 2026 NCT07746895
● Recruiting Respiratory / COPD / Asthma
Automated Oxygen Control in Preterms on Non-invasive Ventilation
What is being tested: Closed-loop automated oxygen control (CLAC) systems that automatically adjust oxygen delivery in preterm infants on non-invasive ventilation, compared to standard…
05 Aug 2026 NCT07622563
● Recruiting Phase III Oncology
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
What is being tested: RLY-2608 (zovegalisib), a PI3K inhibitor, combined with fulvestrant is being compared against capivasertib (another PI3K inhibitor) plus fulvestrant in patients…
05 Aug 2026 NCT06982521
active not recruiting Phase I / Phase II
First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma
Early-stage trial testing epcoritamab (new antibody) for treatment-resistant B-cell lymphoma, measuring safety, dosing, and effectiveness.
04 Aug 2026 NCT03625037
active not recruiting Phase II Dermatology
A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis
Trial testing lutikizumab injections alone and in combination for moderate to severe eczema over 52 weeks.
04 Aug 2026 NCT06718101
active not recruiting Phase III Diabetes / Metabolic
A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes
Semaglutide injection tested against placebo over five years to see if it slows diabetic eye disease in type 2 diabetes.
04 Aug 2026 NCT03811561
active not recruiting Phase II
An Open-label, Phase 2 Study of ACP-196 (Acalabrutinib) in Subjects With Mantle Cell Lymphoma
Acalabrutinib showed safety and effectiveness in treating patients with relapsed or refractory mantle cell lymphoma.
04 Aug 2026 NCT02213926
● Recruiting Cardiology / Cardiovascular
Middle Meningeal Artery Coagulation During Burr-Hole Drainage for Chronic Subdural Haematoma (BURR-MMA)
What is being tested: Coagulation of the middle meningeal artery (MMA) during standard burr-hole drainage surgery for chronic subdural haematoma, aiming to reduce recurrence…
04 Aug 2026 NCT07549893