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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase I Oncology
Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors
What is being tested: mRNA-4359, a novel immunotherapy agent, is being evaluated for safety and tolerability when administered as monotherapy and in combination with…
14 Jul 2026 NCT05533697
● Recruiting Phase I Oncology
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed
What is being tested: GSK5764227, a novel therapeutic agent, is being evaluated for safety, efficacy, and pharmacokinetics as monotherapy or in combination with other…
14 Jul 2026 NCT06885034
● Recruiting Phase III Oncology
Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer
What is being tested: Zanidatamab (a HER2-directed bispecific antibody) combined with standard chemotherapy (Cisplatin/Gemcitabine ± PD-1/L1 inhibitor) versus chemotherapy alone in advanced HER2-positive biliary…
14 Jul 2026 NCT06282575
active not recruiting Phase III Oncology
A Phase III Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Non Small Cell Lung Cancer (NSCLC) Whose Disease Progressed On or After Prior Anti PD (L)1 Therapy And Platinum Based Chemotherapy
A new drug combination (ceralasertib plus durvalumab) tested against standard chemotherapy in advanced lung cancer patients whose disease progressed despite previous immunotherapy.
13 Jul 2026 NCT05450692
active not recruiting Phase III Oncology
A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer
Trial comparing a new drug combination (Dato-DXd plus durvalumab) against standard chemotherapy plus pembrolizumab for triple-negative breast cancer.
13 Jul 2026 NCT06112379
● Recruiting
A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)
Study tracking how geographic atrophy (vision loss from AMD) progresses in older adults, examining structural changes and links to genetics or lifestyle factors.
13 Jul 2026 NCT07144137
● Recruiting Phase I / Phase II Rare Diseases
A Clinical Trial of PR001 (LY3884961) in Patients With Peripheral Manifestations of Gaucher Disease (PROCEED)
LY3884961 (PR001) safety and tolerability study in adults with peripheral Gaucher disease across multiple dose levels over five years.
13 Jul 2026 NCT05487599
● Recruiting Gastroenterology
The Dirty Nappy Study
What is being tested: A machine-learning algorithm designed to automatically detect cholestasis (reduced or blocked bile flow) in newborns by analyzing patterns in clinical…
13 Jul 2026 NCT07697872
● Recruiting Oncology
TRAcking Thoracic Cancer Evolution Through Therapy (Rx) EVO
What is being tested: TRACERx EVO tracks tumour evolution and genetic changes throughout treatment in patients with early- and late-stage NSCLC, SCLC, and pleural…
13 Jul 2026 NCT05628376
● Recruiting Cardiology / Cardiovascular
Comprehensive LEFt Atrial Appendage Occlusion With Rhythm Restoration
What is being tested: This trial evaluates a combined procedure using the Volt PFA System for atrial fibrillation ablation alongside the Amulet 2 device…
13 Jul 2026 NCT07523620
● Recruiting Phase IV Cardiology / Cardiovascular
Clinical Trial in Patients With Barth Syndrome- 4TAZPower
Intervention being tested: Once-daily subcutaneous injection of elamipretide in genetically confirmed Barth syndrome, evaluated over 72 weeks in a Phase 3b/4 randomised, double-blind, placebo-controlled…
13 Jul 2026 NCT07531251
● Recruiting Oncology
To Assess the Correlation of High-resolution Specimen PET-CT Imaging, Using the XEOS AURA 10 PET-CT, With the Histopathology Results and Long-term Outcome of Patients Undergoing Resective Cancer Surgery.
What is being tested: High-resolution specimen PET-CT imaging using the XEOS AURA 10 scanner to evaluate resected cancer specimens intraoperatively, comparing imaging findings with…
13 Jul 2026 NCT06970275
● Recruiting Phase I Oncology
A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of LRK-4189 Alone and in Combination in Patients With Solid Tumors
What is being tested: LRK-4189, an investigational agent, is being evaluated as a monotherapy and in combination regimens for treating solid tumors, with particular…
13 Jul 2026 NCT07498725
● Recruiting Phase II
A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis
Trial tested whether ianalumab injections could safely improve diffuse cutaneous systemic sclerosis compared to placebo.
10 Jul 2026 NCT06470048
active not recruiting Cardiology / Cardiovascular
Exploring the Long-term Cardiovascular Effects of Vaping
A two-year study comparing heart and lung function across 200 people who vape, smoke, both, or neither to assess vaping's long-term cardiovascular safety.
10 Jul 2026 NCT05757934
active not recruiting Phase III Oncology
Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)
Adding rilvegostomig to standard chemotherapy after biliary tract cancer surgery may improve outcomes compared to chemotherapy alone.
10 Jul 2026 NCT06109779
● Recruiting Phase II
EXACT Study: A Blinded Study in Patients With Alport Syndrome to Evaluate Exaluren Efficacy and Safety
What is being tested: Exaluren, a therapeutic agent designed to enable read-through of nonsense mutations in COL4A3/4/5 genes, is being evaluated in a randomized,…
10 Jul 2026 NCT07523581
● Recruiting Phase III Diabetes / Metabolic
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
What is being tested: Elecoglipron, a novel therapeutic agent, is being evaluated for efficacy and safety in reducing weight in adults with obesity or…
10 Jul 2026 NCT07667803
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
What is being tested: Finerenone (a non-steroidal mineralocorticoid receptor antagonist) versus placebo in patients with heart failure and reduced ejection fraction (HFrEF) to evaluate…
10 Jul 2026 NCT06033950
● Recruiting Cardiology / Cardiovascular
Post-Market Clinical Follow Up Study With Navitor Valve
What is being tested: The Navitor TAVI (Transcatheter Aortic Valve Implantation) System is undergoing post-market evaluation to assess its safety profile and clinical performance…
10 Jul 2026 NCT06008080
● Recruiting Phase II Cardiology / Cardiovascular
Comparative Evaluation of Sustained meChanical AsPiration Thrombectomy and no Thrombus Modification for Pre-stent Thrombus bUrden Reduction in Patients With Acute Myocardial Infarction Study: the CAPTURE AMI Study
Treatment being tested: Sustained mechanical aspiration thrombectomy versus standard percutaneous coronary intervention (PCI) without thrombus modification in STEMI patients with angiographically confirmed high thrombus…
10 Jul 2026 NCT07687576
● Recruiting Phase I Oncology
A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )
LY4152199 is a novel investigational agent being evaluated for dose-optimisation, safety, and efficacy in patients with relapsed or refractory B-cell malignancies who have failed…
10 Jul 2026 NCT07101328
active not recruiting Phase III Oncology
Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Osimertinib (TAGRISSO) (ROSY-T)
Osimertinib continuation study for cancer patients benefiting from treatment in previous trials.
09 Jul 2026 NCT05629234
● Recruiting Infectious Disease
Clinical Outcomes Study of the Nexel Total Elbow
Nexel Total Elbow implant study confirms it's safe and works well for new and repeat elbow replacement surgery.
09 Jul 2026 NCT02469662
active not recruiting Phase III Diabetes / Metabolic
Extension Trial Evaluating the Long-term Safety and Efficacy of Dasiglucagon in Children With Congenital Hyperinsulinism
Long-term safety study of dasiglucagon injections in children with congenital hyperinsulinism, following earlier trial completion. (Word count: 19)
09 Jul 2026 NCT03941236
active not recruiting Phase III
Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 in Clinical Trials
Patients who received OAV101 for spinal muscular atrophy are being monitored for five years to check long-term safety and effectiveness.
09 Jul 2026 NCT05335876
● Recruiting Phase II Cardiology / Cardiovascular
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
What is being tested: CDR132L, a novel therapeutic agent, is being evaluated at different doses versus placebo to assess its effects on cardiac structure…
09 Jul 2026 NCT06979362
● Recruiting Phase II Oncology
A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer
What is being tested: Telisotuzumab adizutecan (a novel targeted therapy) combined with standard chemotherapy (oxaliplatin, fluorouracil, folinic acid), bevacizumab, and panitumumab in metastatic colorectal…
09 Jul 2026 NCT06820463
● Recruiting Phase I Oncology
Study of ORIC-944 in Patients With Metastatic Prostate Cancer
What is being tested: ORIC-944, a novel therapeutic agent, is being evaluated both as monotherapy and in combination with androgen receptor pathway inhibitors (ARPIs)…
09 Jul 2026 NCT05413421
● Recruiting
Registry for Patients With X-Linked Hypophosphatemia
What is being tested: This international prospective registry collects observational data on treatment patterns, disease progression, and long-term outcomes in patients with X-Linked Hypophosphatemia…
09 Jul 2026 NCT03193476
● Recruiting Phase I Oncology
A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
NXP900 is a first-in-human investigational agent being tested in a dose escalation and expansion study to determine safety, tolerability, and optimal dosing in patients…
09 Jul 2026 NCT05873686
● Recruiting Phase II Oncology
A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
What is being tested: Telisotuzumab adizutecan (a novel antibody-drug conjugate targeting HER3) administered intravenously as monotherapy or combined with osimertinib (EGFR tyrosine kinase inhibitor),…
09 Jul 2026 NCT07155187
● Recruiting Diabetes / Metabolic
Low EnerGy DiEt iN Adolescents With Obesity and Type 2 Diabetes: The LEGEND Study
Testing: A feasibility study investigating recruitment/retention rates for low energy diet (LED) interventions in adolescents with type 2 diabetes and obesity, with measurement of…
09 Jul 2026 NCT06572345
● Recruiting Cardiology / Cardiovascular
Abbott Structural Heart Device Registry
What is being tested: Safety and performance of Abbott's structural heart devices in real-world clinical practice, using data collected from routine hospital procedures rather…
09 Jul 2026 NCT06590467
● Recruiting Phase III Oncology
Surovatamig as Consolidation Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable (IGHV)
What is being tested: Surovatamig (a subcutaneous monoclonal antibody) administered as consolidation therapy following initial treatment in patients with CLL/SLL, focusing on therapeutic efficacy…
09 Jul 2026 NCT07509151
● Recruiting Phase I / Phase II
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
Gene therapy trial testing whether a single injection can enable the body to produce its own clotting factor in severe haemophilia B patients.
08 Jul 2026 NCT06379789
active not recruiting Phase I Neurology
A Study to Assess THN391 in Subjects With Alzheimer’s Disease
Early-stage trial testing whether THN391 drug is safe and tolerable in Alzheimer's disease patients compared to placebo.
08 Jul 2026 NCT06814730
active not recruiting Phase III Oncology
177Lu-PSMA-617 vs. Androgen Receptor-Directed Therapy in the Treatment of Progressive Metastatic Castrate Resistant Prostate Cancer
Radioactive lutetium treatment improved survival compared to hormone therapy in men with advanced prostate cancer resistant to standard hormonal treatment.
08 Jul 2026 NCT04689828
active not recruiting Phase III
Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA)
Depemokimab was compared to mepolizumab for treating difficult-to-control EGPA in adults already on standard treatment.
08 Jul 2026 NCT05263934
active not recruiting
LIQUIBAND FIX8® for Ventral Incisional Hernia
Real-world safety and performance data on LiquiBand FIX8, a CE-marked adhesive device for securing mesh in ventral incisional hernia repair.
08 Jul 2026 NCT07295379
active not recruiting Phase III
A Study to Test How Safe Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Alone Are and How Well They Work in Adult Patients With Generalized Myasthenia Gravis
Trial testing two new drugs alone and combined for generalised myasthenia gravis, measuring safety, effectiveness, and how the body responds.
08 Jul 2026 NCT05070858
active not recruiting Phase III Oncology
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma
Trial testing if adding epcoritamab injections to standard rituximab and lenalidomide improves outcomes in adults with relapsed/refractory follicular lymphoma.
08 Jul 2026 NCT05409066
active not recruiting
Entropy-based Physiological Signal Analysis in Patients With Obstructive Sleep Apnoea
Study examines whether CPAP therapy reduces physiological signal complexity in obstructive sleep apnoea patients over six months.
08 Jul 2026 NCT07406620
active not recruiting Phase I / Phase II
Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma
Testing whether combining vorasidenib with standard chemotherapy is safe and effective for IDH-mutant brain tumours.
08 Jul 2026 NCT06478212
active not recruiting Phase II Infectious Disease
Study of Bepirovirsen in Participants Living With Human Immunodeficiency Virus and Chronic Hepatitis B Virus Infection (B-Focus)
Bepirovirsen compared to placebo for treating people with both HIV and hepatitis B infection, measuring effectiveness and safety.
08 Jul 2026 NCT06497504
● Recruiting Oncology
Robotic Prostatectomy Artificial Intelligence Low Pressure Pain (RALP) Trial
What is being tested: Feasibility of using artificial intelligence to review operative outcomes, specifically pain levels, when comparing two commonly used robotic surgical devices…
08 Jul 2026 NCT06915909
● Recruiting Phase IV Rheumatology
Stopping PPI Therapy in Inactive IBD
What is being tested: The feasibility and safety of withdrawing proton pump inhibitor (PPI) therapy in patients with inactive inflammatory bowel disease (IBD), with…
08 Jul 2026 NCT07691138
● Recruiting Rheumatology
NAZA – Nottingham/Astra ZenecA Prospective IBD Cohort Study
What is being tested: This observational cohort study compares inflammatory markers between patients with inflammatory bowel disease (IBD) and non-IBD controls to identify potential…
08 Jul 2026 NCT06956703
● Recruiting Cardiology / Cardiovascular
A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
What is being tested: The trial compares two coronary imaging strategies—a calcium modification approach guided by coronary CT angiography (CCTA) versus standard imaging protocols—to…
08 Jul 2026 NCT07286578
● Recruiting Phase II Oncology
KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis
What is being tested: Anti-CD19 chimeric antigen receptor T-cell (CAR-T) therapy, a genetically modified T-cell immunotherapy designed to target and eliminate CD19-expressing B cells…
08 Jul 2026 NCT06193889