Trial Radar

Study tracking safety and outcomes of a shoulder implant system over 10 years following surgery.

Weekly GLM101 treatment tested against placebo for a rare genetic disorder affecting protein processing in children and adults.

What is being tested: Cabotegravir ultra long-acting (CAB ULA) plus rilpivirine ultra-acting (RPV ULA) injections are being compared against standard long-acting formulations (CAB LA…

What is being tested: CSL889 (human hemopexin) administered intravenously in a phase 2 randomized controlled trial to evaluate safety, efficacy, and pharmacokinetics in managing…

What is being tested: ASC30, an oral once-daily medication, is being evaluated for efficacy and safety in reducing weight and improving glycaemic control in…

What is being tested: AZD0120 (a novel therapeutic agent) as consolidation/maintenance therapy following standard induction regimens (IsaVRd or DRd) compared to continuous standard therapy…

Device being tested: The Coroflex® ISAR NEO coronary stent system is undergoing post-market clinical follow-up to verify its safety and performance profile in real-world…

What is being tested: A personalised cardiac rehabilitation programme called MICROFIT combining high-intensity interval exercise (HIIT) and dietary advice, designed to improve outcomes in…

What is being tested: TAK-755, an investigational therapeutic agent, is being evaluated for safety and efficacy in treating acute ischemic stroke caused by blood…

What is being tested: A combined prehabilitation programme (ReHIIT) integrating resistance exercise training with high-intensity interval training in healthy adults to establish baseline physiological…

What is being tested: Sacituzumab tirumotecan (sac-TMT), an antibody-drug conjugate targeting Trop-2, is being evaluated as a potential new treatment for locally advanced or…

Study tracking safety and effectiveness of ceramic hip resurfacing implant over ten years, comparing it to metal versions.

Palazestrant versus standard hormone therapy in advanced breast cancer that's progressed on previous endocrine treatment plus CDK4/6 inhibitor.

Gene therapy AVB-101 delivered to the brain as one-time treatment for early-onset dementia caused by progranulin protein deficiency.

Concizumab daily injections tested in haemophilia A/B patients to prevent bleeds over 2-4 years.

Early-stage study testing a new cancer drug (tuvusertib) alone and combined with niraparib in advanced solid tumors to assess safety and effectiveness.

New drug bomedemstat compared to standard treatment for essential thrombocythemia patients who don't respond to or tolerate hydroxyurea.

A feasibility study testing whether a culturally adapted mindfulness and compassion programme is acceptable and deliverable in Thai secondary schools.

What is being tested: Early time-restricted eating (eTRE), where all daily meals are consumed within a specific time window, and its effects on health…

What is being tested: Adjuvant (post-surgical) therapy combining Intismeran (V940), a personalized neoantigen vaccine, with or without pembrolizumab coformulated with berahyaluronidase alfa (MK-3475A), a…

What is being tested: Safety and performance of GORE® ACUSEAL Vascular Graft, a synthetic vascular access device for haemodialysis in patients with end-stage renal…

What is being tested: Personal environmental exposure monitoring combined with home environmental assessments in children with chronic respiratory conditions to identify and characterise environmental…

What is being tested: The VDyne Transcatheter Tricuspid Valve Replacement System, a minimally invasive device designed to replace the tricuspid valve in patients with…

What is being tested: Long-term safety and performance of the GORE® TAG® Conformable Thoracic Stent Graft with ACTIVE CONTROL System in treating thoracic aortic…

Trial testing a new drug (LP352) against placebo for seizures in children and adults with severe developmental epilepsy over two years.

A device inserted into the coronary sinus improves blood flow and symptoms in patients with chest pain despite normal coronary arteries.

SURPASS-3 Trial Summary A phase 2 trial testing a new cell therapy alone or combined with immunotherapy in women with recurrent ovarian cancer.

Testing RO7269162 drug versus placebo in people with early-stage Alzheimer's disease brain changes over 90 weeks.

Trial testing a new sickle cell drug in children to check how the body processes it and whether it's safe over 96 weeks.

Trial testing efgartigimod IV dosing in teenagers with chronic immune thrombocytopenia to find correct treatment dose.

Long-term study showing octreotide depot injections safely and effectively control acromegaly symptoms in routine clinical practice over two years.

AZD5148 antibody reduces repeat Clostridioides difficile infections in adults compared to placebo.

A drug (sonefpeglutide) tested in patients with severe bowel disease to see if injections are safe and effective.

Long-term safety and effectiveness study of itepekimab injections for adults with chronic nasal polyps inadequately controlled by standard treatment.

What is being tested: A blood test measuring circulating progastrin (hPG80) and transposable elements (TEs) to predict colorectal cancer or polyps in adults referred…

What is being tested: AI-assisted MRI technology designed to improve the speed, accuracy, and consistency of brain and spinal cord imaging interpretation for MS…

What is being tested: AZD0120, a dual CAR T cell therapy targeting CD19 and BCMA, is being investigated as a potential treatment for adults…

What is being tested: Non-invasive mapping technology to identify and eliminate ventricular tachycardia in patients with structural heart disease from previous myocardial infarction, potentially…

What is being tested: M3554 is an anti-GD2 antibody-drug conjugate (ADC) being evaluated for dose optimisation and safety assessment in patients with advanced soft…

What is being tested: The study investigates the mechanisms underlying Cerebellar Mutism Syndrome (CMS), a postoperative complication affecting up to 25% of children undergoing…

What is being tested: TT-702 is a novel drug candidate undergoing evaluation for safety, tolerability, and optimal dosing in patients with advanced solid tumours,…

Maralixibat safely reduced severe itching in patients with cholestatic liver disease who hadn't responded to other treatments.

SureSmile clear aligners tested across three gum-line designs to check safety and accuracy of tooth movements.

New drug tested for Duchenne muscular dystrophy in patients whose genetic mutations can be treated by skipping exon 44.

A trial testing whether a microcurrent stimulation device applied through the eyelid safely improves vision in intermediate-to-advanced dry age-related macular degeneration.

CD19 CAR T-cell therapy tested for safety and effectiveness in patients with relapsed/refractory brain lymphoma.

Real-world study examining how ATTR amyloidosis patients present, are treated, and their outcomes including quality of life and disability.

Multicenter registry tracking uveal melanoma patients over time to understand disease progression and support new treatment development.

Gene therapy SRP-1003 tested for safety and effectiveness in patients with type 1 myotonic dystrophy.

ALXN2030 drug tested against placebo to see if it improves kidney damage from antibody rejection in transplant patients.