Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Women's Health Rheumatology Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase III Oncology
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
What is being tested: Daraxonrasib (RMC-6236), a novel RAS(ON) inhibitor, is being evaluated for safety and efficacy as adjuvant therapy in resected pancreatic ductal…
25 Aug 2026 NCT07252232
● Recruiting Phase I Dermatology
A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)
Study comparing how the body processes nusinersen delivered via an implantable device versus lumbar puncture in spinal muscular atrophy patients.
24 Aug 2026 NCT06555419
active not recruiting Oncology
PASS of Paediatric Patients Initiating Selumetinib
Study monitoring safety of selumetinib (a cancer drug) in children with neurofibromatosis type 1 nerve tumours in routine clinical practice.
24 Aug 2026 NCT05388370
active not recruiting Phase III
Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)
Anifrolumab injection versus placebo tested in early systemic sclerosis patients to assess effectiveness and safety.
24 Aug 2026 NCT05925803
● Recruiting Phase II Rheumatology
A Study of Zasocitinib (TAK-279) in Adults With Active Crohn’s Disease
What is being tested: Zasocitinib (TAK-279), an investigational therapy targeting cellular and molecular mechanisms of inflammation, is being evaluated for its efficacy in treating…
24 Aug 2026 NCT07403968
● Recruiting Phase II Respiratory / COPD / Asthma
Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis
What is being tested: ABBV-142, an investigational therapeutic agent, is being evaluated for its safety profile and effects on disease progression in adult patients…
24 Aug 2026 NCT07230288
● Recruiting Gastroenterology
Plant-Protein Dominant Tube Feed Study
Plant-based tube feeds tested against animal-based feeds for home patients over 12 months, measuring tolerance, compliance, and physical outcomes.
21 Aug 2026 NCT07422935
active not recruiting Phase III
A Study to Evaluate the Safety and Efficacy of Zilganersen (ION373) in Patients With Alexander Disease (AxD)
Zilganersen improves or stabilizes movement in patients with Alexander disease, a rare neurological disorder.
21 Aug 2026 NCT04849741
active not recruiting Phase III Cardiology / Cardiovascular
Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury
Botulinum toxin injections tested against placebo for treating leg stiffness after stroke or brain injury.
21 Aug 2026 NCT03992404
● Recruiting Cardiology / Cardiovascular
Comparing the Effects of Newer Pacemakers and Their Effects on the Heart and Valve Function in the Short-term.
What is being tested: This trial compares conventional pacemakers (with transvalvular leads through the heart valve) against newer pacemaker designs to evaluate their effects…
21 Aug 2026 NCT07534917
● Recruiting Phase III Oncology
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
What is being tested: Sofetabart Mipitecan (Sofe-M), a novel therapeutic agent being evaluated across three study parts in patients with ovarian, peritoneal, and fallopian…
21 Aug 2026 NCT07213804
active not recruiting Phase II Oncology
A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment
Trial testing PF-07220060 with fulvestrant versus standard treatment in advanced hormone-receptor-positive breast cancer.
20 Aug 2026 NCT06105632
● Recruiting Phase II Gastroenterology
Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis
Vamifeport reduced liver iron levels in adults with hereditary hemochromatosis, a genetic iron overload disorder.
20 Aug 2026 NCT07332091
● Recruiting Gastroenterology
How the Brain and Body Recover After a Wrist Fracture
Study testing whether blood markers, brain scans, and body-map tests can predict who develops chronic pain after wrist fracture.
20 Aug 2026 NCT07777081
active not recruiting Phase III Oncology
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)
Adding niraparib to standard prostate cancer treatment improves progression-free survival in men with specific DNA repair gene mutations.
20 Aug 2026 NCT04497844
active not recruiting
Observational GORE® VIABAHN® Endoprosthesis With PROPATEN Bioactive Surface Global Registry
Registry tracking real-world outcomes in patients receiving Gore Viabahn stent grafts with bioactive surface coating.
20 Aug 2026 NCT04907240
● Recruiting Mental Health / Psychiatry
The Effect of 5-hydroxytryptophan on ADHD Traits and Eye Movements
Trial testing whether a natural supplement (5-HTP) can improve concentration and attention problems by increasing serotonin levels.
20 Aug 2026 NCT07777328
active not recruiting Oncology
Chemotherapy and Maximal Tumor Debulking of Multi-organ Colorectal Cancer Metastases
Chemotherapy plus surgery/ablation versus chemotherapy alone for colorectal cancer spread to multiple organs.
20 Aug 2026 NCT01792934
● Recruiting
Total Shoulder Arthroplasty Multi-Center Registry
A multi-centre study tracking clinical outcomes in patients having anatomic or reverse total shoulder replacement surgery.
20 Aug 2026 NCT03511586
● Recruiting Phase I Neurology
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL921 in Healthy Participants and Participants With Alzheimer’s Disease
Drug being tested: DNL921 is a novel investigational agent undergoing Phase 1/1b evaluation for safety, tolerability, pharmacokinetics, and pharmacodynamics in both healthy volunteers and…
20 Aug 2026 NCT07758595
● Recruiting Respiratory / COPD / Asthma
UK SMA Patient Registry
What is being tested: The UK SMA Patient Registry is establishing a comprehensive database to collect clinical, genetic, and outcome data from patients with…
20 Aug 2026 NCT04292574
● Recruiting Cardiology / Cardiovascular
Severe Complications During Ventricular Tachycardia or Premature Ventricular Complex Ablation
What is being tested: This observational study characterizes severe complications occurring during ventricular tachycardia (VT) and premature ventricular complex (PVC) ablation procedures, collecting retrospective…
20 Aug 2026 NCT07777744
● Recruiting Phase I Cardiology / Cardiovascular
A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma
Treatment being tested: Cevostamab (a novel therapeutic agent) administered as monotherapy or in combination with established multiple myeloma regimens (pomalidomide/dexamethasone or daratumumab/dexamethasone) to evaluate…
20 Aug 2026 NCT04910568
active not recruiting Phase II
Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patients
Tisagenlecleucel CAR-T cell therapy for high-risk B-cell leukaemia patients with minimal residual disease after initial treatment.
19 Aug 2026 NCT03876769
● Recruiting Phase II Dermatology
Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis
Multi-drug trial testing new treatments for moderate to severe eczema in adults.
19 Aug 2026 NCT06947993
active not recruiting Phase III
Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension.
Remibrutinib versus placebo and omalizumab for chronic urticaria uncontrolled by antihistamines over 24-52 weeks.
19 Aug 2026 NCT06042478
● Recruiting
Impact of Footwear on Gait in Unilateral Transtibial Amputees
Study testing whether different shoe types affect walking ability, balance and comfort in amputees using prosthetic legs.
19 Aug 2026 NCT07685496
● Recruiting Oncology
A Study to Identify Breast Cancer (IDBC)
What is being tested: A novel blood-based diagnostic test (Syantra DX Breast Cancer) designed to identify breast cancer through biomarker detection in blood samples,…
19 Aug 2026 NCT04495244
● Recruiting Diabetes / Metabolic
Development of a Non-invasive Screening Tool to Predict Metabolic Dysfunction-associated Steatotic Liver Disease
What is being tested: Development and validation of a non-invasive screening tool to predict metabolic dysfunction-associated steatotic liver disease (MASLD), potentially replacing the need…
19 Aug 2026 NCT04873258
● Recruiting Phase III Cardiology / Cardiovascular
Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment
Treatment Being Tested: Continued access to benralizumab (Fasenra), a monoclonal antibody targeting IL-5 receptor alpha, for patients with eosinophilic airway diseases who have demonstrated…
19 Aug 2026 NCT07444567
● Recruiting Phase III Cardiology / Cardiovascular
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
What is being tested: Oral levosimendan efficacy and safety in patients with pulmonary hypertension combined with heart failure with preserved ejection fraction (PH-HFpEF), with…
19 Aug 2026 NCT07288398
● Recruiting Cardiology / Cardiovascular
Multimodal Biomarkers in Coronary Artery Disease Pathogenesis: The Oxford Acute Myocardial Infarction Study (OXAMI Study)
What is being tested: The study investigates multiple biomarkers (biological markers) to understand how coronary artery disease develops and progresses, particularly in patients experiencing…
19 Aug 2026 NCT07772570
active not recruiting Phase III Oncology
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer
Adding olaparib to abiraterone improves outcomes versus abiraterone alone in men with newly-diagnosed advanced prostate cancer.
18 Aug 2026 NCT03732820
● Recruiting Diabetes / Metabolic
GLycaemic Outcomes With Whey Protein in ageING
What is being tested: A placebo-controlled trial investigating whether consuming whey protein before meals improves glucose control in older adults with type 2 diabetes,…
18 Aug 2026 NCT07285811
● Recruiting Phase I Cardiology / Cardiovascular
A Research Study on the Effects of NNC0537-1482 in Participants With Heart Failure
Investigational Agent: NNC0537-1482 is a novel drug being evaluated for safety, tolerability, and pharmacological efficacy in heart failure patients—addressing an unmet therapeutic need in…
18 Aug 2026 NCT07218627
● Recruiting Oncology
Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer
What is being tested: Long-term safety outcomes of nipple-sparing mastectomy (NSM) as a risk-reducing procedure in women carrying high-penetrance breast cancer susceptibility gene mutations…
18 Aug 2026 NCT06888388
● Recruiting Phase III Diabetes / Metabolic
A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism
Study testing whether ersodetug added to standard treatment reduces low blood sugar episodes in patients with insulin-producing tumours.
17 Aug 2026 NCT06881992
active not recruiting Phase I
A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma
Early-stage trial testing a new antibody drug (cevostamab) alone or combined with existing treatments for hard-to-treat multiple myeloma.
17 Aug 2026 NCT04910568
active not recruiting Phase II Rheumatology
A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)
Trial testing whether a new drug called Afimetoran works better than placebo for treating active lupus.
17 Aug 2026 NCT04895696
● Recruiting Gastroenterology
A Prospective Study of Pediatric Participants up to 16 Years of Age With Methylmalonic Acidemia (MMA) Due to Mutations in the MMUT Gene
Study Summary for UK Clinicians This observational study tracks children with methylmalonic acidemia to identify reliable blood markers and clinical signs indicating disease activity…
17 Aug 2026 NCT07432880
● Recruiting Phase II Oncology
A PoC Study to Evaluate Treatments’ Efficacy by Monitoring MRD Using ctDNA in HR-positive/HER2-negative EBC Population
What is being tested: A phase II study evaluating adjuvant treatment efficacy in HR-positive/HER2-negative early breast cancer by using circulating tumour DNA (ctDNA) as…
17 Aug 2026 NCT05708235
● Recruiting Phase III Respiratory / COPD / Asthma
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
What is being tested: Depemokimab, a novel biologic therapy, is being evaluated as an add-on treatment to standard care in Type 2 asthma patients…
17 Aug 2026 NCT07456033
● Recruiting Phase II Oncology
DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.
Treatment Being Tested: The combination of dabrafenib (a BRAF inhibitor) and trametinib (a MEK inhibitor) in patients with BRAF V600 mutation-positive cancers across multiple…
17 Aug 2026 NCT07440290
● Recruiting Cardiology / Cardiovascular
Arterial Stiffness in Children and Young People With Hypertension and Chronic Kidney Disease
What is being tested: The study investigates arterial stiffness (hardening of arteries) in children and young people with hypertension and/or chronic kidney disease, examining…
17 Aug 2026 NCT07768865
● Recruiting Cardiology / Cardiovascular
Nailfold Capillaroscopy in PH
What is being tested: Nailfold capillaroscopy (microscopic examination of blood vessels in the nail fold) as a non-invasive diagnostic tool to identify pulmonary hypertension…
17 Aug 2026 NCT07768644
● Recruiting Phase II Oncology
A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder
What is being tested: The combination of enfortumab vedotin (an antibody-drug conjugate targeting Nectin-4) with pembrolizumab (a PD-1 checkpoint inhibitor) as a bladder-preserving alternative…
17 Aug 2026 NCT07475806
● Recruiting Phase III Respiratory / COPD / Asthma
Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.
Trial testing upadacitinib tablet/liquid versus tocilizumab injection/infusion for systemic juvenile arthritis in children aged 1-18 over 52 weeks.
14 Aug 2026 NCT05609630
● Recruiting Phase II / Phase III Oncology
A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma
Trial testing new drug telisotuzumab adizutecan combined with chemotherapy versus standard treatment for advanced pancreatic cancer.
14 Aug 2026 NCT07490301
active not recruiting Phase III Oncology
A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)
Testing two new drug combinations against standard treatment for advanced kidney cancer, measuring survival and disease progression.
14 Aug 2026 NCT04736706
active not recruiting Phase I / Phase II Oncology
Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancer
ODM-208 showed acceptable safety in advanced prostate cancer patients, supporting further development of this new treatment.
14 Aug 2026 NCT03436485