Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
Explore Trial Collections Follow research updates
All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
🔬
Trial Radar

Clinical Trial Intelligence

active not recruiting Rheumatology
STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon
Trial comparing patellar versus quadriceps tendon grafts for ACL reconstruction, with or without additional lateral stabilisation surgery.
18 Jun 2026 NCT03935750
active not recruiting Phase III Cardiology / Cardiovascular
A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIa AL Amyloidosis (CARES)
CAEL-101 antibody tested to remove amyloid deposits, improve survival and reduce heart hospitalisations in advanced light chain amyloidosis patients.
18 Jun 2026 NCT04512235
active not recruiting Phase III
A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment
Imetelstat improves survival compared to standard treatment in patients with advanced myelofibrosis who haven't responded to JAK inhibitors.
18 Jun 2026 NCT04576156
● Recruiting Respiratory / COPD / Asthma
Serological and PCR Testing for COVID-19
What is being tested: The trial evaluates existing and newly developed COVID-19 PCR and antibody (serological) tests to establish methodologies that deliver rapid and…
18 Jun 2026 NCT04404062
● Recruiting Phase I Oncology
Study of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours
What is being tested: AZD4956, a novel investigational agent, is being evaluated as both a monotherapy and in combination with established anti-cancer treatments in…
18 Jun 2026 NCT07446855
● Recruiting Phase I Oncology
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
What is being tested: An umbrella trial evaluating multiple treatment combination regimens across seven cohorts in patients with metastatic or inoperable locally advanced breast…
18 Jun 2026 NCT03424005
● Recruiting Phase I Oncology
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
What is being tested: S241656 is a novel investigational agent being evaluated in a first-in-human trial as monotherapy and in combination with established anti-cancer…
18 Jun 2026 NCT05786924
● Recruiting Phase I
Phase 1 Study of ADX-626 in Healthy Participants
Early safety testing of new drug ADX-626 in healthy volunteers to check it's tolerable and how the body processes it.
17 Jun 2026 NCT07081503
active not recruiting Phase II Rheumatology
A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE)
Trial testing IMVT-1402 injection versus placebo for skin lupus, measuring safety and effectiveness over 52 weeks.
17 Jun 2026 NCT06980805
active not recruiting Phase III Dermatology
A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis
Ruxolitinib cream safely and effectively reduced moderate eczema in children and teenagers aged 6-17 years.
17 Jun 2026 NCT06832618
● Recruiting Cardiology / Cardiovascular
PATHWAY-RCT: Preventing Admission To Hospital With Attr cardiomyopathY
Remote weight monitoring with telephone doctor support reduces hospital admissions in patients with heart amyloidosis.
17 Jun 2026 NCT05098665
active not recruiting
Registry for Patients Undergoing Penile Prosthesis Implantation for Male Erectile Dysfunction
Registry tracking outcomes in men receiving surgical penile implants for erectile dysfunction.
17 Jun 2026 NCT03849586
active not recruiting Phase III Gastroenterology
Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis
Tofacitinib tablet oral treatment for children aged 2-17 with moderate-severe ulcerative colitis, measuring remission rates after 44 weeks.
17 Jun 2026 NCT04624230
● Recruiting Respiratory / COPD / Asthma
Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS
What is being tested: A randomized controlled trial evaluating whether patients with COPD and chronic bronchitis who switch from cigarette smoking to tobacco heating…
17 Jun 2026 NCT07108166
● Recruiting Respiratory / COPD / Asthma
Breathlessness Perceptions Within Respiratory Diseases
What is being tested: This trial investigates how physiological, psychological, and functional factors—including breathing patterns—influence breathlessness perception in respiratory disease patients, moving beyond traditional…
17 Jun 2026 NCT07648082
● Recruiting Cardiology / Cardiovascular
Mechanisms of Myocardial Injury and Ischemia in Patients With Rapid Atrial Fibrillation
What is being tested: The study investigates the mechanisms of myocardial injury in rapid atrial fibrillation patients by measuring troponin levels (cardiac biomarker) and…
17 Jun 2026 NCT06951100
● Recruiting Oncology
Postoperative Electrical Muscle Stimulation Two
What is being tested: Electrical muscle stimulation (EMS) applied postoperatively to prevent or reduce skeletal muscle atrophy in patients experiencing immobility or inactivity following…
17 Jun 2026 NCT06964438
● Recruiting Phase II Neurology
A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson’s Disease
What is being tested: Dapansutrile, an anti-inflammatory medication that inhibits the NLRP3 inflammasome pathway, is being evaluated to determine whether reducing neuroinflammation can slow…
17 Jun 2026 NCT07157735
● Recruiting Phase II Neurology
A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years
Treatment being tested: mRNA-1195, a novel mRNA-based therapeutic, is being investigated for its safety profile and tolerability in multiple sclerosis patients, with evaluation of…
17 Jun 2026 NCT06735248
● Recruiting Phase I Gastroenterology
A Phase 1/2, Open-Label, Single and Multiple Ascending Dose Study of CRMA-1001 in Adults With Chronic Hepatitis B
Drug being tested: CRMA-1001, a novel therapeutic agent undergoing Phase 1/2 evaluation for safety, tolerability, and efficacy in adults with chronic hepatitis B using…
17 Jun 2026 NCT07200193
● Recruiting Infectious Disease
Ganciclovir Resistant/Refractory Cytomegalovirus Infection in SOT Recipients and HSCT Patients
What is being tested: Risk factors and clinical characteristics associated with ganciclovir-resistant or refractory cytomegalovirus (CMV) infection in immunocompromised patients following solid organ transplant…
17 Jun 2026 NCT05234723
● Recruiting Phase II Respiratory / COPD / Asthma
A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)
Treatment being tested: Axatilimab at three different dose levels in patients with recurrent or refractory active chronic graft versus host disease (cGVHD) who have…
17 Jun 2026 NCT04710576
● Recruiting Respiratory / COPD / Asthma
Innate Immunity in COPD
What is being tested: This trial investigates innate immune mechanisms in COPD to understand why some smokers develop the disease while others do not,…
17 Jun 2026 NCT05743582
● Recruiting Cardiology / Cardiovascular
RCT of Implantable Defibrillators in Patients With Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure
What is being tested: BRITISH is evaluating whether implantable cardioverter-defibrillators (ICDs) improve outcomes in non-ischaemic cardiomyopathy patients with myocardial scar and severe systolic heart…
17 Jun 2026 NCT05568069
● Recruiting Cardiology / Cardiovascular
Thrombectomy in PE
What is being tested: Catheter-based thrombectomy (mechanical removal of blood clots using a special tube) as a treatment for pulmonary embolism, a potentially life-threatening…
17 Jun 2026 NCT07650435
● Recruiting Phase III Oncology
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
Treatment being tested: Dato-DXd (a HER2-directed antibody-drug conjugate) combined with rilvegostomig (an immunostimulatory agent), versus rilvegostomig alone or pembrolizumab monotherapy, as first-line therapy for…
17 Jun 2026 NCT06357533
● Recruiting Phase I Oncology
A Phase 1/2 Study of STP938 (Dencatistat) for Adult Subjects With Relapsed/Refractory B-Cell and T-Cell Lymphomas
Drug and Mechanism: STP938 (Dencatistat) is being tested as a monotherapy agent in a dose-escalation Phase 1 study followed by Phase 2 cohort expansion…
17 Jun 2026 NCT05463263
active not recruiting Phase I Oncology
A Study to Learn How Safe the Study Treatment Actinium-225-macropa-pelgifatamab (BAY3546828) is, How it Affects the Body, How it Moves Into, Through and Out of the Body, and About Its Anticancer Activity in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)
First-in-human trial testing safety, tolerability, and cancer-fighting activity of a new radioactive targeted treatment for advanced prostate cancer.
15 Jun 2026 NCT06052306
active not recruiting Phase III Infectious Disease
Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With Biktarvy
Trial comparing a new two-drug HIV combination against standard three-drug treatment in people with well-controlled infection.
15 Jun 2026 NCT06333808
active not recruiting
Deuterium Labelled Carbohydrate Oxidation During High Intensity Exercise
Study using labelled glucose to measure how much glucose the body burns during moderate and high-intensity exercise.
15 Jun 2026 NCT07646665
active not recruiting Respiratory / COPD / Asthma
Experiences of Managing Sleep Disordered Breathing in Children With Cerebral Palsy.
Sleep breathing problems are common in children with cerebral palsy but often missed; this study explores patient and family experiences of treatment.
15 Jun 2026 NCT06753370
active not recruiting Phase I / Phase II Gastroenterology
Study to Test the Safety and How Well Patients With Severe Hemophilia A Respond to Treatment With BAY 2599023 (DTX 201), a Drug Therapy That Delivers a Healthy Version of the Defective Factor VIII Gene Into the Nucleus of Liver Cells Using an Altered, Non-infectious Virus (AAV) as a “Shuttle”
Gene therapy trial testing safety and effectiveness of BAY 2599023 for severe hemophilia A treatment.
15 Jun 2026 NCT03588299
● Recruiting Infectious Disease
Ganciclovir Resistant/Refractory Cytomegalovirus Infection in SOT Recipients and HSCT Patients
Study examined risk factors for ganciclovir-resistant CMV infection in organ and stem cell transplant patients to improve future prevention and treatment.
15 Jun 2026 NCT05234723
active not recruiting Phase II / Phase III Oncology
A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Participants With PIK3CA-Mutant, Hormone Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer
Adding inavolisib to standard breast cancer treatment improves outcomes in patients with specific genetic mutations and advanced hormone-receptor-positive disease.
15 Jun 2026 NCT04191499
active not recruiting Phase II
Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow
Naxitamab (anti-GD2 antibody) plus GM-CSF treats high-risk neuroblastoma resistant to initial or salvage chemotherapy, with five-year follow-up.
15 Jun 2026 NCT03363373
● Recruiting
The UK 22 Week Study
Study observing outcomes in 22-week babies receiving active care across UK hospitals to identify common patterns and improve future treatment.
15 Jun 2026 NCT07616778
● Recruiting
Radiation Free Study
LumiGuide imaging reduces fluoroscopy time during complex aortic repair procedures compared to standard X-ray guidance.
15 Jun 2026 NCT06549348
● Recruiting
International CRDS Registry
A new registry tracks a rare genetic heart rhythm condition caused by RYR2 gene faults to understand its features and best treatments.
15 Jun 2026 NCT06508164
● Recruiting
PMCF Study of the Axonics SNM System Model 5101 (R20) for the Indication of OAB
A long-term safety and effectiveness study of the Axonics sacral nerve stimulation device for overactive bladder.
15 Jun 2026 NCT06789406
● Recruiting Cardiology / Cardiovascular
Mechanisms of Myocardial Injury and Ischemia in Patients With Rapid Atrial Fibrillation
Study investigates whether heart damage markers in rapid atrial fibrillation patients indicate blocked arteries or heart attack.
15 Jun 2026 NCT06951100
● Recruiting Respiratory / COPD / Asthma
Breathlessness Perceptions Within Respiratory Diseases
What is being tested: This cross-sectional study investigates how physiological, psychological, functional, and breathing pattern factors influence breathlessness perception and health-related quality of life…
15 Jun 2026 NCT07648082
● Recruiting Phase I
Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of LAI MMV055 Alone and in Combination With MMV371 in Healthy Participants
Testing two new long-acting injectable medicines alone and combined for safety, tolerability and how the body processes them in healthy volunteers.
15 Jun 2026 NCT07011511
active not recruiting Phase I / Phase II Oncology
Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer
Trial testing a new breast cancer drug (elacestrant) combined with five existing treatments to find safe doses and effectiveness.
12 Jun 2026 NCT05563220
● Recruiting Phase III Neurology
Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder
Radiprodil versus placebo for rare genetic brain disorder causing seizures and developmental problems, with open-label extension.
12 Jun 2026 NCT07224581
● Recruiting Phase III Dermatology
A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
Trial testing whether subcutaneous mezagitamab maintains stable platelet counts in adults with immune thrombocytopenia compared to placebo.
12 Jun 2026 NCT06722235
● Recruiting Phase III Respiratory / COPD / Asthma
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
Intervention being tested: Filgotinib, a JAK1-selective inhibitor, is being evaluated for efficacy, safety, tolerability, and pharmacokinetics in paediatric and adolescent patients with ulcerative colitis…
12 Jun 2026 NCT06865417
● Recruiting Phase I Oncology
AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
What is being tested: AMG 410, a novel KRAS-targeted agent, is being evaluated as monotherapy and in combination regimens for safety, tolerability, pharmacokinetics, and…
12 Jun 2026 NCT07094113
● Recruiting Cardiology / Cardiovascular
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
What is being tested: Real-world effectiveness, safety, and treatment patterns of mavacamten (a novel cardiac myosin inhibitor) compared with standard therapies in symptomatic obstructive…
12 Jun 2026 NCT05489705
● Recruiting Phase III Cardiology / Cardiovascular
Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke
What is being tested: Sovateltide, a neuroprotective agent designed to protect brain tissue during acute ischaemic stroke and potentially promote neural repair in the…
12 Jun 2026 NCT05691244
● Recruiting Phase III Oncology
Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)
What is being tested: Belzutifan (MK-6482), a hypoxia-inducible factor (HIF-2α) inhibitor, is being evaluated in an extension study for patients with advanced solid tumors…
12 Jun 2026 NCT07405164