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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2231 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2231 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

active not recruiting Phase I / Phase II
An Open-label Study of Povetacicept in Participants With Autoimmune Cytopenias
New drug povetacicept tested in adults with autoimmune blood disorders to assess safety and effectiveness over six months.
28 Jul 2026 NCT05757570
● Recruiting Phase II
A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults
Trial testing whether injected Corabotase into head and neck muscles safely and effectively prevents episodic or chronic migraines in adults.
28 Jul 2026 NCT06625060
active not recruiting Phase II
A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)
Trial testing a new cancer drug (zilovertamab vedotin) alone and combined with other treatments in patients with hard-to-treat B-cell blood cancers.
28 Jul 2026 NCT05458297
● Recruiting Gastroenterology
StratCare Trial 2: Evaluating the Clinical and Cost-effectiveness of AI-driven Stratified Care for Depression
What is being tested: An AI-driven stratified care approach for depression that aims to match patients to the most appropriate treatment intensity from the…
28 Jul 2026 NCT06567340
● Recruiting Phase III Respiratory / COPD / Asthma
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
What is being tested: Depemokimab, a novel therapeutic agent, is being evaluated as an add-on treatment for moderate to severe COPD patients with Type…
28 Jul 2026 NCT07177339
● Recruiting Cardiology / Cardiovascular
Early Detection and IntervenTion in Heart Failure
What is being tested: Early detection and intervention strategies in heart failure to identify patients before symptomatic disease develops and prevent progression of cardiac…
28 Jul 2026 NCT07731490
● Recruiting Phase III Oncology
A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer
Treatment being tested: A combination of two targeted therapies—avutometinib (a MEK inhibitor) and defactinib (a FAK inhibitor)—compared against standard investigator-selected treatments in patients with…
28 Jul 2026 NCT06072781
● Recruiting
MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)
FASTER-HIP Summary Comparing hip replacement versus surgical pinning for older adults with hip fractures, assessing effects on survival, mobility, and hospital discharge within one…
27 Jul 2026 NCT07244211
● Recruiting Phase III
A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD
This trial tests whether intravenous AOC 1020 safely and effectively treats facioscapulohumeral muscular dystrophy compared to placebo.
27 Jul 2026 NCT07038200
active not recruiting Phase III Oncology
Study of Pembrolizumab Given Prior to Surgery and in Combination With Radiotherapy Given Post-surgery for Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-689)
Pembrolizumab before and after surgery with radiotherapy improves survival in advanced head and neck cancer compared to radiotherapy alone.
27 Jul 2026 NCT03765918
active not recruiting Phase III Rheumatology
Subcutaneous Anifrolumab in Adult Patients With Systemic Lupus Erythematosus
Subcutaneous anifrolumab (an interferon-blocking drug) improved outcomes in moderate-to-severe lupus patients already on standard treatment.
27 Jul 2026 NCT04877691
● Recruiting Gastroenterology
Integrating Exposure and Response Prevention and Habit Reversal Techniques to Treat a Tourettic Subtype of Obsessive-Compulsive Disorder (Tourettic OCD)
Combined exposure therapy and habit reversal training reduces symptoms better than either treatment alone in adults with obsessive-compulsive disorder and tics.
27 Jul 2026 NCT07725926
● Recruiting Phase II Neurology
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
What is being tested: Remternetug, a potential disease-modifying treatment, is being evaluated for its effectiveness in slowing cognitive decline in asymptomatic individuals at risk…
27 Jul 2026 NCT06647498
● Recruiting Phase II Neurology
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
What is being tested: Investigational disease-modifying treatments in individuals carrying genetic mutations that cause early-onset Alzheimer's disease, with evaluation of biomarker effects, safety, and…
27 Jul 2026 NCT05552157
● Recruiting Mental Health / Psychiatry
The Mouth Matters in Mental Health Trial -2
What is being tested: A link worker intervention designed to support people with severe mental health difficulties in attending routine dental appointments, with evaluation…
27 Jul 2026 NCT07470437
● Recruiting Phase III Oncology
Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint In
What is being tested: A phase 3 randomized trial comparing two experimental combination regimens (N-803 plus tislelizumab with docetaxel, or prior failed PD-1/PD-L1 checkpoint…
27 Jul 2026 NCT06745908
● Recruiting Phase II Oncology
A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies
Being Tested: Long-term safety, tolerability, and efficacy of adagrasib (a KRAS G12C inhibitor) as continued treatment in patients with solid tumours, predominantly NSCLC, who…
27 Jul 2026 NCT07415031
● Recruiting Phase II Oncology
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
What is being tested: Plixorafenib (FORE8394), a BRAF inhibitor, is being evaluated for efficacy and safety in patients with locally advanced, metastatic, or recurrent/progressive…
27 Jul 2026 NCT05503797
active not recruiting Phase III
A Study of Acalabrutinib vs Investigator’s Choice of Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in R/R CLL
Acalabrutinib compared to chemotherapy plus antibody therapy for previously treated blood cancer patients.
24 Jul 2026 NCT02970318
active not recruiting Phase I
A Phase 1b Study to Investigate Safety and Tolerability of ARGX-119 in Adult Participants With DOK7-Congenital Myasthenic Syndromes (CMS)
Early-stage trial testing safety of ARGX-119 infusions in adults with DOK7 muscle weakness syndrome.
24 Jul 2026 NCT06436742
● Recruiting Phase III Rheumatology
Apremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis
Apremilast was tested against placebo in children aged 5-17 with juvenile psoriatic arthritis to assess its effectiveness.
24 Jul 2026 NCT04804553
active not recruiting Phase III
Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR)
Long-term safety study of secukinumab (an IL-17 inhibitor) in patients with polymyalgia rheumatica to assess tolerability and adverse effects.
24 Jul 2026 NCT06331312
● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)
Trial testing nerandomilast tolerance and effectiveness in children aged 2-17 with interstitial lung disease over 2.5-5 years.
24 Jul 2026 NCT07366034
● Recruiting Respiratory / COPD / Asthma
A Study in Adults to Learn About Inherited Alpha-1 Antitrypsin Deficiency (AATD) and AATD Related Liver Problems
What is being tested: A study evaluating the pathophysiology of inherited alpha-1 antitrypsin deficiency (AATD), specifically how abnormal Z-AAT protein accumulates in liver cells…
24 Jul 2026 NCT06512454
● Recruiting Phase III Cardiology / Cardiovascular
Apremilast Pediatric Study in Children With Active Oral Ulcers Associated With Behçet’s Disease
Intervention tested: Apremilast (a phosphodiesterase-4 inhibitor) versus placebo for treating oral ulcers in children with Behçet's disease, addressing a significant unmet need in pediatric…
24 Jul 2026 NCT04528082
● Recruiting Phase III Cardiology / Cardiovascular
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
Treatment tested: Inclisiran, a PCSK9 inhibitor administered via subcutaneous injection, being evaluated for its ability to lower LDL cholesterol in paediatric patients with homozygous…
24 Jul 2026 NCT06597006
● Recruiting Phase III Oncology
Vorasidenib Maintenance for IDH Mutant Astrocytoma
What is being tested: Vorasidenib (an IDH inhibitor) as maintenance therapy post-chemoradiotherapy versus placebo in IDH-mutant astrocytoma, with progression-free survival as the primary endpoint.…
24 Jul 2026 NCT06809322
● Recruiting Oncology
Evaluation of the Ileo-anal Pouch in FAP (ENDOPOL)
What is being tested: This RCT compares dye-based chromoendoscopy versus virtual chromoendoscopy (NBI/BLI technology) for detecting adenomas during surveillance pouchoscopy in FAP patients with…
24 Jul 2026 NCT07726771
● Recruiting Phase II Oncology
A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
What is being tested: The trial evaluates imzokitug added to pumitamig plus platinum-doublet chemotherapy versus pumitamig plus chemotherapy alone as first-line treatment for locally…
24 Jul 2026 NCT07680764
active not recruiting Phase I / Phase II Oncology
First-in-Human Study of ICT01 in Patients With Advanced Cancer
New antibody drug (ICT01) tested alone and with pembrolizumab in advanced cancer patients to find safe doses and effectiveness.
23 Jul 2026 NCT04243499
active not recruiting Phase III Oncology
A Study of SGN-B6A Versus Docetaxel in Previously Treated Non-small Cell Lung Cancer
Trial comparing new cancer-targeting drug sigvotatug vedotin versus standard docetaxel chemotherapy in previously treated advanced lung cancer patients.
23 Jul 2026 NCT06012435
active not recruiting Phase II / Phase III
A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy
Zanubrutinib reduced protein in urine in primary membranous nephropathy patients and was compared against standard tacrolimus treatment.
23 Jul 2026 NCT05707377
active not recruiting Phase III Oncology
Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10)
MRTX849 plus cetuximab compared to chemotherapy for advanced bowel cancer with specific KRAS mutation.
23 Jul 2026 NCT04793958
● Recruiting Phase II Rheumatology
A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
Phase 2 trial testing two immunosuppressive drugs in patients with treatment-resistant lupus and rheumatoid arthritis.
23 Jul 2026 NCT06570798
active not recruiting Phase III Oncology
A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy
Trial testing whether adding tiragolumab to atezolizumab improves outcomes in advanced oesophageal cancer after chemoradiotherapy.
23 Jul 2026 NCT04543617
● Recruiting Phase I Oncology
Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors
What is being tested: MOMA-313, an oral therapeutic agent, is undergoing Phase 1 evaluation for safety, tolerability, pharmacokinetics, and preliminary anti-tumour activity in patients…
23 Jul 2026 NCT06545942
● Recruiting Phase III Neurology
An Evaluation of Treatments for Sustained Clinical Response (18 Months) in Symptomatic Alzheimer’s Disease
What is being tested: A Phase 3 trial evaluating multiple treatment approaches for sustained clinical response over 18 months in symptomatic Alzheimer's disease, using…
23 Jul 2026 NCT07724132
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
What is being tested: The combination of finerenone (a non-steroidal mineralocorticoid receptor antagonist) plus empagliflozin (an SGLT2 inhibitor) versus standard care in hospitalised heart…
23 Jul 2026 NCT06024746
● Recruiting Cardiology / Cardiovascular
Neuropsychiatric Outcomes and Disrupted Sleep Following Acquired Brain Injury
What is being tested: The relationship between sleep quality and neuropsychiatric outcomes (mental health problems) in patients following acquired brain injury from stroke or…
23 Jul 2026 NCT07215195
● Recruiting Cardiology / Cardiovascular
Placental Biology in Health and Disease
What is being tested: This trial investigates placental biological mechanisms underlying pre-eclampsia (hypertension with organ damage) and gestational diabetes mellitus (abnormal glucose metabolism in…
23 Jul 2026 NCT07470320
● Recruiting Oncology
Is the Use of a Steam Mask an Effective Treatment for Paediatric Chalazion in Comparison to Traditional Warm Compresses?
What is being tested: This trial compares the effectiveness of a steam mask versus traditional warm compresses as treatments for chalazion (a common eyelid…
23 Jul 2026 NCT07721779
● Recruiting Phase I Oncology
A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors
What is being tested: INCA33890, a novel investigational agent, is undergoing a dose-escalation safety and tolerability study in patients with advanced or metastatic solid…
23 Jul 2026 NCT05836324
active not recruiting Phase II Dermatology
A Study Evaluating APG777 in Atopic Dermatitis
Trial testing a new drug (APG777) to treat moderate-to-severe eczema, comparing different doses against placebo over 106 weeks.
22 Jul 2026 NCT06395948
active not recruiting Phase II Oncology
A Study of Ramucirumab (LY3009806) or Merestinib (LY2801653) in Advanced or Metastatic Biliary Tract Cancer
Trial testing two new drugs combined with standard chemotherapy for advanced biliary tract cancer to assess effectiveness and safety.
22 Jul 2026 NCT02711553
● Recruiting Phase I / Phase II Oncology
Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers
Trial testing ubamatamab alone or combined with cemiplimab in recurrent ovarian and other MUC16-positive cancers, assessing safety, dosing, and effectiveness.
22 Jul 2026 NCT03564340
● Recruiting Phase III Oncology
EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma
Trial testing whether adding immunotherapy (pembrolizumab) to standard glioblastoma treatment improves survival compared to standard treatment alone.
22 Jul 2026 NCT06556563
● Recruiting Phase III Gastroenterology
A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD
Trial testing a surgically implanted eye device that delivers ranibizumab every 36 weeks for age-related macular degeneration.
22 Jul 2026 NCT06847542
active not recruiting Phase III Oncology
Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49)
Pembrolizumab added to chemotherapy versus chemotherapy alone for advanced hormone receptor-positive breast cancer, with PFS as primary endpoint in PD-L1 positive patients.
22 Jul 2026 NCT04895358
active not recruiting Cardiology / Cardiovascular
STOP Persistent AF PAS
STOP Persistent AF Post Approval Study A worldwide study tracking real-world outcomes in patients receiving treatment for persistent atrial fibrillation outside controlled trial settings.
22 Jul 2026 NCT05005949
● Recruiting Phase III Diabetes / Metabolic
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
What is being tested: Ribupatide (KAI-9531), a novel once-weekly subcutaneous injection, is being evaluated for weight reduction in people with obesity without diabetes, compared…
22 Jul 2026 NCT07284979