Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase II Respiratory / COPD / Asthma
Therapeutic Equivalence of CHF5993 pMDI 100/6/12.5 µg HFA-152a in Subjects With Mild to Moderate Asthma
What is being tested: Therapeutic equivalence of CHF5993 pMDI (a combination inhaler containing beclomethasone/formoterol/glycopyrronium) formulated with HFA-152a propellant versus the standard formulation, to confirm…
25 Jun 2026 NCT07301736
● Recruiting Phase II Cardiology / Cardiovascular
A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction
What is being tested: A low-energy diet intervention to improve functional status and symptoms in patients with heart failure with preserved ejection fraction (HFpEF),…
25 Jun 2026 NCT05887271
● Recruiting Phase II Oncology
Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL
Drug being tested: Surovatamig (AZD0486), a novel monotherapy agent, is being evaluated for efficacy, safety and tolerability in treating relapsed/refractory B-cell non-Hodgkin lymphoma in…
25 Jun 2026 NCT06526793
active not recruiting Phase II Gastroenterology
Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure)
B-Sure Trial Summary This study tracks how long the benefits of bepirovirsen (an experimental hepatitis B treatment) last in patients after they stop taking…
24 Jun 2026 NCT04954859
active not recruiting Rare Diseases
A Prospective Study to Observe & Describe Clinical Outcomes of Alglucosidase Alfa Treatment in Patients ≤6 Months of Age With Infantile-onset Pompe Disease (IOPD)
Early alglucosidase alfa treatment in infantile-onset Pompe disease improves survival without breathing support and motor development at 52 weeks.
24 Jun 2026 NCT04848779
● Recruiting Phase III
A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy
Trial testing a new drug (volrustomig) versus monitoring in head and neck cancer patients after chemoradiotherapy.
24 Jun 2026 NCT06129864
● Recruiting Gastroenterology
ENDO1000 – A UK-wide Endometriosis Research Project
ENDO1000 collects symptom data via app from 3000 UK people with endometriosis to identify diagnostic markers and personalised treatment approaches.
24 Jun 2026 NCT07240883
● Recruiting Phase III
Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
This trial tests whether pridopidine slows ALS progression compared to placebo in adults over 96 weeks.
24 Jun 2026 NCT07322003
active not recruiting Phase III
A Study to Evaluate the Effect of Venglustat Tablets on Left Ventricular Mass Index in Male and Female Adult Participants With Fabry Disease
Venglustat compared to standard treatment for reducing heart thickening in adults with Fabry disease over 18 months.
24 Jun 2026 NCT05280548
● Recruiting Phase I Respiratory / COPD / Asthma
A Study to Compare the Relative Potency of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152a to HFA-134a in Mild Asthmatics Aged 18 to 65 Inclusive
What is being tested: The study compares the effectiveness and potency of salbutamol (albuterol) delivered via metered dose inhalers using two different propellant systems—HFA-152a…
24 Jun 2026 NCT06433921
● Recruiting Phase I Oncology
Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies
Drug being tested: CCS1477 (inobrodib), a novel therapeutic agent being evaluated for safety, tolerability, pharmacokinetics and biological activity in a Phase 1/2a trial across…
24 Jun 2026 NCT04068597
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant
What is being tested: A novel combination therapy pairing elranatamab (a bispecific antibody engaging T-cells and myeloma cells) with daratumumab and lenalidomide, compared against…
24 Jun 2026 NCT05623020
active not recruiting Phase III
A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Non-Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-NTDT)
Mitapivat reduced anaemia in patients with non-transfusion-dependent thalassemia compared to placebo.
23 Jun 2026 NCT04770753
● Recruiting Phase II
A Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor Neuropathy
Phase 2 trial testing Claseprubart safety and effectiveness in adults with multifocal motor neuropathy.
23 Jun 2026 NCT06537999
active not recruiting Phase I / Phase II Oncology
Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options
Entrectinib tested in children with advanced solid or brain tumours carrying specific gene fusions to find safe doses and effectiveness.
23 Jun 2026 NCT02650401
● Recruiting Phase III Mental Health / Psychiatry
NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Trial testing whether adding NBI-1065845 to existing depression treatment works better than placebo for improving symptoms.
23 Jun 2026 NCT06963021
active not recruiting Phase II Oncology
A Study of Olaparib Prior to Surgery and Chemotherapy in Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
Olaparib given before surgery and chemotherapy to shrink recurrent ovarian, peritoneal, or fallopian tube cancers.
23 Jun 2026 NCT02489006
● Recruiting Cardiology / Cardiovascular
Physiological Versus Right Ventricular Outcome Trial Evaluated for Bradycardia Treatment Upgrades
What is being tested: Comparison of physiological pacing strategies versus traditional right ventricular (RV) pacing in patients undergoing first-time pacemaker implantation, specifically evaluating whether…
23 Jun 2026 NCT06052475
● Recruiting Oncology
Glasgow Low-dose CT and AI-based Diagnostics to Case Find Lung Cancer and Other Cardio-respiratory Long-term Conditions – Feasibility Study
What is being tested: Low-dose CT scanning combined with artificial intelligence diagnostics to detect lung cancer early and identify other cardio-respiratory long-term conditions in…
23 Jun 2026 NCT07372508
● Recruiting Phase III Oncology
A Study of ZL-1310 Versus Investigator’s Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)
What is being tested: ZL-1310, a novel therapeutic agent, is being compared against standard investigator-selected treatments in patients with relapsed small cell lung cancer…
23 Jun 2026 NCT07218146
● Recruiting Phase III Diabetes / Metabolic
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Intervention being tested: Enicepatide (RO7795068), a dual GLP-1/GIP receptor agonist at multiple doses, compared with placebo for weight management and glycaemic control in patients…
23 Jun 2026 NCT07351058
● Recruiting Phase III Diabetes / Metabolic
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Treatment being tested: Enicepatide (RO7795068), a dual GLP-1/GIP receptor agonist, is being evaluated at multiple doses versus placebo for weight management efficacy and safety…
23 Jun 2026 NCT07351045
● Recruiting Cardiology / Cardiovascular
Nutritional Screening in Cardiovascular Disease
What is being tested: A comprehensive nutritional screening protocol combining questionnaires, blood/urine biomarkers, grip strength measurement, and body composition analysis in patients undergoing heart…
23 Jun 2026 NCT07409519
● Recruiting Phase I Oncology
A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008)
MK-1045 is being evaluated as a potential treatment for two distinct subtypes of non-Hodgkin lymphoma: follicular lymphoma (indolent/slow-growing) and diffuse large B-cell lymphoma (aggressive/fast-growing),…
23 Jun 2026 NCT07519772
active not recruiting Phase III Oncology
Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing
Ongoing access to avelumab treatment for patients benefiting from it in completed Pfizer trials, with safety monitoring.
22 Jun 2026 NCT05059522
active not recruiting Phase II / Phase III Rheumatology
A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
Litifilimab injections tested for efficacy and safety in adults with active cutaneous lupus unresponsive to antimalarial therapy.
22 Jun 2026 NCT05531565
active not recruiting Mental Health / Psychiatry
Designing and Evaluating a Classroom-Based Mental Health Programme for Adolescents.
A feasibility study testing whether a classroom mental health programme about psychosis and coping strategies works in Northern Ireland secondary schools.
22 Jun 2026 NCT07660874
active not recruiting Phase II
Acalabrutinib and Rituximab in Previously Untreated Mantle Cell Lymphoma
Acalabrutinib plus rituximab showed promise as a gentler first-line treatment option for elderly or frail patients with mantle cell lymphoma.
22 Jun 2026 NCT05004064
● Recruiting Phase III Neurology
A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
This trial tests whether inhaled alprazolam stops prolonged seizures faster than placebo in people aged 12+.
22 Jun 2026 NCT05077904
● Recruiting Phase I / Phase II Rare Diseases
A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)
Single intravenous gene therapy infusion (SGT-003) tested for safety and effectiveness in children with Duchenne muscular dystrophy across age groups.
22 Jun 2026 NCT06138639
● Recruiting Phase I Oncology
Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer
What is being tested: EP0062, a novel therapeutic agent, is being evaluated as a single agent and in combination with standard-of-care treatments to determine…
22 Jun 2026 NCT05573126
● Recruiting Gastroenterology
Natural History of Wilson Disease
What is being tested: A registry collecting clinical data and biological specimens from Wilson disease patients to establish optimal diagnostic testing methods and disease…
22 Jun 2026 NCT03334292
● Recruiting Phase I Oncology
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
Treatment being tested: Tulmimetostat (DZR123/CPI-0209), a novel investigational agent evaluated as monotherapy and combined with enzalutamide, in a first-in-human trial assessing safety, tolerability, pharmacokinetics,…
22 Jun 2026 NCT04104776
● Recruiting Phase I Oncology
A Study to Assess the Safety and Anti-Tumor Activity of REGN7945 in Combination With Linvoseltamab in Adult Participants With Relapsed/Refractory Multiple Myeloma
What is being tested: REGN7945 combined with linvoseltamab (REGN5458), two experimental bispecific antibodies, in adults with relapsed/refractory multiple myeloma; this is the first-in-human study…
22 Jun 2026 NCT06669247
● Recruiting Phase I Cardiology / Cardiovascular
A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)
Treatment being tested: Linvoseltamab, an experimental monoclonal antibody targeting serum amyloid A, is being evaluated for safety and efficacy in adults with relapsed or…
22 Jun 2026 NCT06292780
● Recruiting Cardiology / Cardiovascular
FeetSee Thermal Images Collection Protocol in Diabetes Patients
What is being tested: FeetSee thermal imaging technology is being evaluated as a potential early detection tool for diabetic foot ulcers by collecting thermal…
22 Jun 2026 NCT07300163
● Recruiting Phase III Oncology
A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)
What is being tested: Sacituzumab govitecan-hziyah (Sac-TMT), an antibody-drug conjugate targeting TROP-2, is being evaluated as a treatment option for advanced ovarian cancer patients…
22 Jun 2026 NCT07318558
active not recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy
New cancer drug inavolisib plus fulvestrant compared with alpelisib plus fulvestrant for advanced breast cancer resistant to previous treatments.
18 Jun 2026 NCT05646862
active not recruiting Diabetes / Metabolic
Effect of a Sugar Replacement on Blood Glucose Levels in Healthy Adults
A sugar replacement called Oligomate® lowered blood sugar spikes after drinking compared to glucose in healthy people.
18 Jun 2026 NCT06714552
active not recruiting Phase III Oncology
A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer
Testing two immunotherapy combinations after chemotherapy and radiotherapy in advanced lung cancer patients.
18 Jun 2026 NCT05221840
● Recruiting Phase II Mental Health / Psychiatry
A Phase 2a Efficacy, Safety, Tolerability, and PK Study of SYT-510 in Participants With Generalized Anxiety Disorder
Single dose of experimental drug SYT-510 tested against placebo in anxiety patients to assess safety, effectiveness and body response.
18 Jun 2026 NCT07478744
● Recruiting Phase III Diabetes / Metabolic
Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
Treatment being tested: KAI-9531, a novel subcutaneous injection administered weekly, is being evaluated for its efficacy in reducing body weight compared to placebo in…
18 Jun 2026 NCT07284875
● Recruiting Cardiology / Cardiovascular
Pancreas Lipotoxicity in T2D: Edinburgh Diabetes Remission Study (EDRS)
What is being tested: The study investigates pancreatic fat accumulation (lipotoxicity) as a mechanism in type 2 diabetes development and whether weight loss interventions…
18 Jun 2026 NCT07364045
● Recruiting Phase III Cardiology / Cardiovascular
A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
What is being tested: Lepodisiran, an investigational therapy designed to reduce lipoprotein(a) [Lp(a)] levels, is being evaluated for its ability to reduce coronary artery…
18 Jun 2026 NCT07613294
● Recruiting Phase III Cardiology / Cardiovascular
Timing to Restart Direct Oral Anticoagulants After Traumatic Intracranial Haemorrhage
What is being tested: The optimal timing for restarting direct oral anticoagulants (DOACs) in older patients after traumatic intracranial haemorrhage, comparing early versus delayed…
18 Jun 2026 NCT06322953
● Recruiting Phase III Oncology
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)
Treatment being tested: Two immunotherapy-based regimens for advanced biliary tract cancer (BTC)—rilvegostomig combined with gemcitabine/cisplatin versus durvalumab combined with gemcitabine/cisplatin—compared as first-line therapy in…
18 Jun 2026 NCT07221253
active not recruiting Phase III Oncology
A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician’s Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
Giredestrant versus standard hormone therapy for early breast cancer: a Phase III trial testing a new treatment option.
18 Jun 2026 NCT04961996
active not recruiting Phase III
Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren’s Syndrome
Trial testing whether ianalumab improves symptoms and safety in people with active Sjögren's syndrome compared to placebo.
18 Jun 2026 NCT05349214
active not recruiting Phase III Infectious Disease
Attachment Inhibitor Comparison in Heavily Treatment Experienced Patients
A new HIV drug (BMS-663068) tested in patients with resistant virus who have failed multiple previous treatments.
18 Jun 2026 NCT02362503
active not recruiting Phase III Diabetes / Metabolic
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
Retatrutide weekly injection tested to reduce heart attacks, strokes, and kidney damage in obese adults over five years.
18 Jun 2026 NCT06383390