Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase III Respiratory / COPD / Asthma
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer’s Disease (ADEPT-2)
Treatment being tested: KarXT, a novel muscarinic M1/M4 receptor agonist, is being evaluated for treating psychosis (including hallucinations, delusions, and agitation) in patients with…
28 Apr 2026 NCT06126224
● Recruiting Cardiology / Cardiovascular
Brain Training to Improve Balance in Parkinson’s Disease
Intervention being tested: A brain training programme designed to improve balance function in people with Parkinson's disease, addressing one of the most disabling symptoms…
28 Apr 2026 NCT05986643
● Recruiting Oncology
IMMUNO-FIT Observational Study
What is being tested: The study investigates how immunotherapy (checkpoint inhibitors) affects physical fitness, quality of life, and treatment tolerance in adults with solid…
28 Apr 2026 NCT07354971
● Recruiting Phase II Cardiology / Cardiovascular
Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)
Drug being tested: REGN13335, an experimental therapeutic agent, is being evaluated for safety and efficacy in adults with pulmonary arterial hypertension (PAH), a condition…
28 Apr 2026 NCT07318597
● Recruiting Phase III Oncology
MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia Vera
Treatment being tested: Ruxolitinib (a JAK1/2 inhibitor) compared against standard first-line therapies (hydroxycarbamide or interferon-alpha) in newly diagnosed high-risk polycythemia vera patients. Patient eligibility…
28 Apr 2026 NCT04116502
● Recruiting Phase III Oncology
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator’s Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
What is being tested: Nemtabrutinib (MK-1026), a novel Bruton's tyrosine kinase (BTK) inhibitor, is being directly compared against standard-of-care BTK inhibitors (ibrutinib or acalabrutinib)…
28 Apr 2026 NCT06136559
● Recruiting Phase I Diabetes / Metabolic
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.
A new weight loss drug (AZD1043) is being tested for safety and effectiveness in overweight and obese adults.
27 Apr 2026 NCT07511205
● Recruiting
A Natural History Study in Participants With Congenital Myasthenic Syndromes (CMS) Due to Mutations in DOK7, MUSK, AGRN, or LRP4
Study tracking symptom changes and quality of life in patients with rare inherited muscle-nerve connection disorders caused by specific genetic mutations.
27 Apr 2026 NCT06078553
active not recruiting Phase II
Adagrasib in Patients With KRASG12C-mutant NSCLC Who Are Elderly or Have Poor Performance Status
Adagrasib showed benefit in elderly or unfit lung cancer patients with KRASG12C mutations who couldn't tolerate standard treatments.
27 Apr 2026 NCT05673187
● Recruiting Phase III Gastroenterology
Extension Study for the Port Delivery System With Ranibizumab (Portal)
Portal Extension Study Summary Implanted drug delivery system releasing ranibizumab shows sustained safety and effectiveness in wet age-related macular degeneration over extended follow-up.
27 Apr 2026 NCT03683251
● Recruiting
HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington’s Disease
HDClarity collects spinal fluid and blood samples from 2500 Huntington's disease patients to identify biomarkers for developing new treatments.
27 Apr 2026 NCT02855476
active not recruiting Phase II
A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases
A trial testing a new cell therapy (tabelecleucel) to treat diseases caused by Epstein-Barr virus infection.
27 Apr 2026 NCT04554914
● Recruiting Phase II / Phase III
A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation
Frexalimab injections compared to tacrolimus tablets in first kidney transplant patients over five years to assess effectiveness and safety.
27 Apr 2026 NCT07412470
● Recruiting Phase I / Phase II
A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK Inhibitors
Testing whether adding roginolisib to ruxolitinib safely improves outcomes in myelofibrosis patients who haven't responded to JAK inhibitors alone.
27 Apr 2026 NCT06887803
● Recruiting Phase III Rheumatology
OLE Study With Filgotinib in JIA
Filgotinib appears safe and effective for long-term use in children with polyarticular or systemic juvenile idiopathic arthritis.
27 Apr 2026 NCT07553182
active not recruiting Phase IV
A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis
Emicizumab treatment improves health, physical activity, and joint damage in teenagers and adults with moderate to severe haemophilia A.
27 Apr 2026 NCT05181618
active not recruiting Dermatology
A Proof-of-Concept Study to Evaluate the Efficacy of NOBO, a Novel Postbiotic, in Controlling Axillary Odor in Healthy Adults
Trial testing whether a yeast-based spray reduces underarm odor compared to placebo in healthy adults.
27 Apr 2026 NCT07547761
● Recruiting Gastroenterology
ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)
What is being tested: ELEVATE is a global registry documenting the natural disease progression of acute hepatic porphyria (AHP) and evaluating real-world safety and…
27 Apr 2026 NCT04883905
● Recruiting Phase III Cardiology / Cardiovascular
A Study of Roxadustat to Treat Anemia in Children and Teenagers With Chronic Kidney Disease
What is being tested: Roxadustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor already approved for treating anaemia in adult CKD patients, is being investigated…
27 Apr 2026 NCT05970172
● Recruiting Phase II Rheumatology
Obe-cel in Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis
What is being tested: Obe-cel, a B-cell targeted therapy designed to eliminate pathogenic B cells in patients with severe, refractory SLE and active lupus…
27 Apr 2026 NCT07053800
● Recruiting Phase III Infectious Disease
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
What is being tested: This Phase 3 trial compares two intravenous antiviral treatments—brincidofovir (BCV) and cidofovir (CDV)—for managing adenovirus (AdV) viremia in allogeneic hematopoietic…
27 Apr 2026 NCT07387367
● Recruiting Rheumatology
Describing Treatment Patterns and Creating an Updated Treatment Flow in an Ulcerative Colitis Population
What is being tested: This trial characterises current treatment patterns and pathways in ulcerative colitis management, developing an updated treatment algorithm to reflect contemporary…
27 Apr 2026 NCT07177209
● Recruiting Phase III Oncology
Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer
What is being tested: The trial evaluates whether adding stereotactic radiosurgery (SRS) to standard systemic immunotherapy or targeted therapy improves central nervous system progression-free…
27 Apr 2026 NCT05522660
● Recruiting Cardiology / Cardiovascular
Hydra Registry – UK
What is being tested: Efficacy and safety of the Hydra transcatheter aortic heart valve (THV) series for transcatheter aortic valve implantation (TAVI) in patients…
27 Apr 2026 NCT06507579
● Recruiting Cardiology / Cardiovascular
Mayo AVC Registry and Biobank
What is being tested: A registry and biobank collecting clinical data and biological samples from patients with arrhythmogenic ventricular cardiomyopathy (AVC) to improve understanding…
27 Apr 2026 NCT03049254
● Recruiting Phase II Cardiology / Cardiovascular
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
What is being tested: Ninerafaxstat, a novel therapeutic agent, is being evaluated for efficacy and safety in symptomatic non-obstructive hypertrophic cardiomyopathy (nHCM) as an…
27 Apr 2026 NCT07023614
● Recruiting Phase II Oncology
DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers
What is being tested: BI 764532 at different doses in patients with advanced small cell lung cancer and other neuroendocrine cancers who have failed…
27 Apr 2026 NCT05882058
● Recruiting Phase II Oncology
A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With Generalized Myasthenia Gravis
Treatment being tested: Efgartigimod PH20 (subcutaneous formulation) – a neonatal Fc receptor (FcRn) inhibitor designed to reduce IgG antibodies in generalized myasthenia gravis (gMG)…
27 Apr 2026 NCT06392386
● Recruiting Phase III Oncology
JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC
What is being tested: JNJ-90301900 (NBTXR3), a nanoparticle therapy activated by radiotherapy, combined with standard radiation therapy ± cetuximab versus radiation therapy ± cetuximab…
27 Apr 2026 NCT04892173
● Recruiting Phase III Oncology
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
What is being tested: The addition of INCB161734 (a KRAS G12D inhibitor) to standard chemotherapy versus chemotherapy alone in patients with metastatic pancreatic cancer…
27 Apr 2026 NCT07522073
● Recruiting Phase I / Phase II
Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma
Trial testing two new cell therapies (KITE-363 and KITE-753) for B-cell lymphoma that hasn't responded to standard treatment.
24 Apr 2026 NCT04989803
● Recruiting Phase III
A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps
New anti-inflammatory injection (itepekimab) tested alongside steroid nasal spray for difficult-to-treat nasal polyps over one year.
24 Apr 2026 NCT06834360
active not recruiting Phase II
A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)
A trial testing whether tebapivat reduces blood transfusion needs in patients with low-risk bone marrow disorders.
24 Apr 2026 NCT05490446
● Recruiting Phase III
REVEAL: A Phase 3 Study of ION582 in Angelman Syndrome
ION582 improved seizures, sleep and developmental outcomes in Angelman syndrome patients with UBE3A deletions or mutations.
24 Apr 2026 NCT06914609
active not recruiting Phase II / Phase III
An International, Multicenter, Randomized, Double-Blind, Parallel Group, Vehicle-Controlled, Phase 2/3 Study With Open-Label Extension Evaluating the Efficacy and Safety of Diacerein 1% Ointment for the Treatment of Generalized Epidermolysis Bullosa Simplex (EBS)
Diacerein ointment tested for safety and effectiveness in treating generalized epidermolysis bullosa simplex blistering disorder.
24 Apr 2026 NCT06073132
active not recruiting Phase I / Phase II Oncology
A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer
Trial testing durvalumab combinations versus standard chemotherapy in patients with advanced triple negative breast cancer.
24 Apr 2026 NCT03742102
● Recruiting Phase II Dermatology
A Dose-ranging Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Galvokimig in Adult Study Participants With Atopic Dermatitis
Trial testing different doses of galvokimig versus placebo in adults with moderate-to-severe eczema to find the most effective safe dose.
24 Apr 2026 NCT07277660
● Recruiting Phase I
A Study to Investigate Andexanet Dosing and the Interaction Between Andexanet and Subsequent Enoxaparin in Healthy Participants
Andexanet alfa dosing study examining how it interacts with subsequent enoxaparin treatment in healthy volunteers.
24 Apr 2026 NCT07312851
active not recruiting Phase I
Multi-modular Chimeric Antigen Receptor Targeting GD2 in Neuroblastoma
A trial testing a new engineered cell therapy for children with difficult-to-treat neuroblastoma, focusing on safety and feasibility.
24 Apr 2026 NCT05990751
active not recruiting Phase I Infectious Disease
COVID-19 Omicron BA.5 Subvariant Dose Finding Infection Study
Researchers tested different doses of Omicron BA.5 virus in vaccinated volunteers to find the optimal dose for future COVID vaccine studies.
24 Apr 2026 NCT06478420
● Recruiting Phase III Gastroenterology
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
What is being tested: Efruxifermin (EFX), an FGF21 analogue, is being evaluated in a randomized controlled trial to assess its efficacy and safety in…
24 Apr 2026 NCT06528314
● Recruiting Phase II Respiratory / COPD / Asthma
Imlifidase Prior to Kidney Transplant in Highly Sensitised Children
What is being tested: Imlifidase, an IgG-degrading enzyme, is being evaluated for its efficacy and safety in enabling successful kidney transplantation in highly sensitized…
24 Apr 2026 NCT05753930
● Recruiting Phase III Cardiology / Cardiovascular
A Study of Migalastat in Pediatric Subjects (2 to
What is being tested: Migalastat, a pharmacological chaperone, is being evaluated for safety, pharmacokinetics, pharmacodynamics, and efficacy in treating paediatric Fabry disease patients aged…
24 Apr 2026 NCT06904261
● Recruiting Cardiology / Cardiovascular
Neurovascular Product Surveillance Registry
What is being tested: This is a post-market surveillance registry monitoring the safety and performance of neurovascular products already in clinical use, rather than…
24 Apr 2026 NCT02988128
● Recruiting Phase IV Cardiology / Cardiovascular
THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE)
Treatment being tested: Thromboprophylaxis (blood clot prevention strategies) in patients undergoing endovenous interventions for superficial varicose veins, which are minimally invasive keyhole procedures performed…
24 Apr 2026 NCT05735639
● Recruiting Phase I Oncology
KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)
What is being tested: Novel treatment combinations pairing enfortumab vedotin with pembrolizumab, investigating whether additional agents can improve outcomes in locally advanced or metastatic…
24 Apr 2026 NCT07232602
● Recruiting Phase II Oncology
Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment
What is being tested: Pumitamig (BNT327), a novel investigational therapy, combined with chemotherapy as first-line or second-line treatment in advanced/metastatic NSCLC, with evaluation of…
24 Apr 2026 NCT06841055
● Recruiting Phase III Oncology
A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer
What is being tested: ARTEMIDE-Lung04 evaluates rilvegostomig (a novel immunotherapy agent) versus pembrolizumab monotherapy as first-line treatment in patients with metastatic non-small cell lung…
24 Apr 2026 NCT06868277
● Recruiting Phase III Oncology
Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT
What is being tested: Mocravimod, a TLR7 agonist, is being evaluated as an adjunctive and maintenance therapy in acute myeloid leukaemia (AML) patients undergoing…
24 Apr 2026 NCT05429632
● Recruiting Phase III Oncology
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
What is being tested: Long-term safety and efficacy of pembrolizumab (an anti-PD-1 immunotherapy) in patients with advanced tumors who are continuing treatment or follow-up…
24 Apr 2026 NCT03486873