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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2236 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2236 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Cardiology / Cardiovascular
iCorMicA – Stratified Medicine in Angina
What is being tested: Stratified medical therapy guided by an adjunctive interventional diagnostic procedure (IDP) during invasive management of angina patients with known coronary…
10 Apr 2026 NCT04674449
● Recruiting Cardiology / Cardiovascular
Inari VISION Registry
What is being tested: The Inari VISION Registry collects real-world performance data on Inari Medical devices and products through prospective, multicenter observation without randomization,…
10 Apr 2026 NCT06600542
● Recruiting Phase II Cardiology / Cardiovascular
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis
What is being tested: CSL300 (clazakizumab), an IL-6 pathway inhibitor, is being evaluated in a two-part trial to identify optimal dosing (phase 2b) and…
10 Apr 2026 NCT05485961
● Recruiting Phase III Cardiology / Cardiovascular
A Study of Navenibart in Participants With Hereditary Angioedema
What is being tested: Navenibart, a subcutaneous treatment for hereditary angioedema (HAE types 1 and 2), is being evaluated in a Phase 3 randomised…
10 Apr 2026 NCT06842823
● Recruiting Cardiology / Cardiovascular
Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
What is being tested: The clinical utility and diagnostic accuracy of smartphone-based ECG devices (AliveCor Kardia) for detecting and managing ST-elevation myocardial infarction (STEMI),…
10 Apr 2026 NCT06271577
● Recruiting Phase III Oncology
A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)
What is being tested: Safety and risk of tumor lysis syndrome (TLS) in treatment-naïve adults with CLL receiving venetoclax combined with either intravenous obinutuzumab…
10 Apr 2026 NCT06428019
● Recruiting Phase III Oncology
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
What is being tested: Rilvegostomig (a novel VEGF inhibitor) combined with fluoropyrimidine chemotherapy and trastuzumab deruxtecan (T-DXd) versus standard trastuzumab plus chemotherapy with pembrolizumab…
10 Apr 2026 NCT06764875
● Recruiting Phase I Oncology
A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment.
What is being tested: Neoadjuvant ipilimumab (an immune checkpoint inhibitor) administered before standard surgical treatment in newly diagnosed glioblastoma patients, evaluating both safety and…
10 Apr 2026 NCT07134842
● Recruiting Phase I Oncology
A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors
What is being tested: YL201 (an investigational cancer therapy) combined with atezolizumab (an immune checkpoint inhibitor) in a phase Ib/II dose escalation and expansion…
10 Apr 2026 NCT07407933
● Recruiting Oncology
Zn-DDC to Target Hypoxia-NFkappaB-CSCs Pathway in Multiple Myeloma
What is being tested: Zn-DDC (Imuthiol), an intravenous agent designed to target cancer stem cells in multiple myeloma by disrupting the hypoxia-NFkappaB-CSC pathway, which…
10 Apr 2026 NCT04234022
● Recruiting Phase III Oncology
A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma
What is being tested: Ficlatuzumab (a hepatocyte growth factor inhibitor) combined with cetuximab versus placebo plus cetuximab in patients with recurrent or metastatic HPV-negative…
10 Apr 2026 NCT06064877
active not recruiting Phase III
Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis
Trial testing selinexor combined with ruxolitinib versus ruxolitinib alone for untreated myelofibrosis patients.
09 Apr 2026 NCT04562389
● Recruiting Phase II
BAY3401016; Biomarker Study Alport
BAY3401016 is a new drug that blocks a protein to slow kidney damage progression in adults with rapidly worsening Alport syndrome.
09 Apr 2026 NCT07211685
active not recruiting Phase II Cardiology / Cardiovascular
Open-label Extension Study of GB002 in Adult Subjects With Pulmonary Arterial Hypertension (PAH)
Long-term safety and effectiveness study of seralutinib, a new drug treatment, in adults with pulmonary arterial hypertension.
09 Apr 2026 NCT04816604
● Recruiting Phase I
Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]GRT6019
This study tracks how the body absorbs, breaks down and eliminates a single dose of an experimental drug called GRT6019.
09 Apr 2026 NCT07479745
active not recruiting Phase III Oncology
Effectiveness Study of Nivolumab Compared to Placebo in Prevention of Recurrent Melanoma After Complete Resection of Stage IIB/C Melanoma
Nivolumab immunotherapy reduced melanoma recurrence risk compared to placebo in high-risk patients after surgery.
09 Apr 2026 NCT04099251
active not recruiting Phase III Oncology
Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)
TAILORx showed hormone therapy alone is sufficient for most women with early-stage hormone-responsive breast cancer, avoiding unnecessary chemotherapy.
09 Apr 2026 NCT00310180
● Recruiting Phase III
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Trial testing two new drugs (pozelimab and cemdisiran) to slow vision loss in advanced age-related macular degeneration.
09 Apr 2026 NCT06541704
● Recruiting Phase I
Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of ALXN2230 in Healthy Participants
ALXN2230 single injection tested for safety and tolerability in healthy volunteers.
09 Apr 2026 NCT07352423
● Recruiting Phase II / Phase III Neurology
Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
BHV-7000 is being tested to see if it works safely in adults with focal epilepsy that doesn't respond to current drugs.
09 Apr 2026 NCT06309966
● Recruiting Phase III Oncology
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
New drug rilvegostomig combined with chemotherapy and trastuzumab deruxtecan tested against standard immunotherapy treatment for advanced HER2-positive stomach cancer.
09 Apr 2026 NCT06764875
● Recruiting Phase III Oncology
A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma
Trial testing whether adding ficlatuzumab to cetuximab improves survival in advanced HPV-negative head and neck cancer.
09 Apr 2026 NCT06064877
● Recruiting Oncology
Zn-DDC to Target Hypoxia-NFkappaB-CSCs Pathway in Multiple Myeloma
One-sentence summary: Researchers are testing whether Imuthiol, a cheap drug toxic to cancer stem cells, could be effective alone or combined with existing myeloma…
09 Apr 2026 NCT04234022
active not recruiting Cardiology / Cardiovascular
CHAMPION-AF Clinical Trial
WATCHMAN FLX device closure of the heart's left atrial appendage works as well as anticoagulant tablets for stroke prevention in atrial fibrillation.
09 Apr 2026 NCT04394546
● Recruiting Phase II Respiratory / COPD / Asthma
Long-term Safety and Efficacy Evaluation of Lunsekimig (SAR443765) in Adult Participants With Asthma.
Lunsekimig (SAR443765) Long-term Asthma Trial Summary Long-term safety and effectiveness study of lunsekimig injection for adults with asthma over 96 weeks.
09 Apr 2026 NCT06609239
● Recruiting Phase II / Phase III Diabetes / Metabolic
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis
A trial testing clazakizumab (an anti-inflammatory drug) to reduce heart disease and death in dialysis patients with inflammation. Word count: 18 words
09 Apr 2026 NCT05485961
● Recruiting Respiratory / COPD / Asthma
Inari VISION Registry
Global registry tracking safety and performance of Inari Medical devices in routine clinical practice across multiple centers.
09 Apr 2026 NCT06600542
● Recruiting Cardiology / Cardiovascular
Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
Smartphone 12-lead ECG device tested against standard machines for accurately diagnosing heart attacks in emergency settings.
09 Apr 2026 NCT06271577
● Recruiting Phase II
Efficacy and Safety of IMVT-1402 in Adult Participants With Primary Sjogren’s Disease With Moderate to Severe Systemic Disease Activity
IMVT-1402 tested against placebo in adults with moderate-to-severe primary Sjögren's disease to assess whether it improves symptoms and is safe.
09 Apr 2026 NCT06979531
● Recruiting Phase II
A Clinical Trial to Evaluate Efficacy and Safety of TransCon CNP Compared With Placebo in Infants (0 to <2 Years of Age) With Achondroplasia
TransCon CNP (navepegritide) weekly injections versus placebo tested for safety and effectiveness in babies with achondroplasia.
08 Apr 2026 NCT06079398
● Recruiting Rheumatology
A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants
Trial comparing treatment options for lupus patients not responding adequately to current standard steroids and immunosuppressive drugs.
08 Apr 2026 NCT07175285
active not recruiting Phase I / Phase II Oncology
GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors
GEN1042 antibody tested alone and combined with pembrolizumab, with or without chemotherapy, in patients with solid tumours.
08 Apr 2026 NCT04083599
● Recruiting Phase I Cardiology / Cardiovascular
Test-retest Study With [18F]FBB in Cardiac Amyloidosis
A study testing whether PET scans reliably detect amyloid buildup in hearts of patients with cardiac amyloidosis.
08 Apr 2026 NCT06790394
active not recruiting Phase III Oncology
A Study of Subcutaneously Injected Epcoritamab Plus Oral Lenalidomide Tablets Compared to Intravenously (IV) Infused Rituximab Plus IV Infused Gemcitabine and IV Infused Oxaliplatin in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Trial comparing injected epcoritamab plus tablets (with or without lenalidomide) to intravenous chemotherapy for relapsed/refractory lymphoma.
08 Apr 2026 NCT06508658
active not recruiting Phase II Oncology
Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Untreated Advanced (Metastatic or Unresectable) Synovial Sarcoma and Myxoid/Round Cell Liposarcoma
Gene-edited T-cell therapy trial testing safety and effectiveness in advanced synovial sarcoma and liposarcoma patients.
08 Apr 2026 NCT05993299
active not recruiting Cardiology / Cardiovascular
Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE)
Laser-based treatment effectively breaks up calcium deposits in coronary arteries, improving blood vessel access during heart procedures.
08 Apr 2026 NCT06181240
● Recruiting Phase II
Clinical Study of Neflamapimod in Patients With Primary Progressive Aphasia
Neflamapimod was tested for safety and effectiveness in patients with a progressive language disorder affecting speech fluency.
08 Apr 2026 NCT07033481
active not recruiting Phase III Oncology
A Phase 3 Trial of Epcoritamab vs Investigator’s Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)
Epcoritamab (injected weekly then fortnightly) compared to standard chemotherapy for people with relapsed/refractory lymphoma ineligible for stem cell transplant.
08 Apr 2026 NCT04628494
active not recruiting Phase II Oncology
Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Treated Advanced (Metastatic or Unresectable) Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
Engineered T-cell therapy trial testing safety and effectiveness in advanced synovial sarcoma or liposarcoma patients.
08 Apr 2026 NCT06703346
● Recruiting Rheumatology
Tight Control of Gouty Arthritis Compared to Usual Care
Patient-led urate monitoring with smartphone support reduces gout flares compared to standard treatment approaches.
08 Apr 2026 NCT05507723
● Recruiting Phase II Infectious Disease
Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa
Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa is Recruiting • Phase II • Infectious Disease • NCT07170917. This is a Phase…
08 Apr 2026 NCT07170917
● Recruiting Phase II Diabetes / Metabolic
FrexalimAB in Preservation of Endogenous insULIN Secretion Compared to Placebo in adUlts and Adolescents on Top of inSulin Therapy (FABULINUS)
FrexalimAB in Preservation of Endogenous insULIN Secretion Compared to Placebo in adUlts and Adolescents on Top of inSulin Therapy (FABULINUS) is Recruiting • Phase…
08 Apr 2026 NCT06111586
● Recruiting Cardiology / Cardiovascular
Metabolic Phenotyping in vEDS
Metabolic Phenotyping in vEDS is Recruiting • Phase not applicable • Cardiology / Cardiovascular • NCT07516496. This research study will investigate whether people with…
08 Apr 2026 NCT07516496
● Recruiting Phase III Cardiology / Cardiovascular
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) is Recruiting • Phase III…
08 Apr 2026 NCT07517263
● Recruiting Cardiology / Cardiovascular
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP) is Recruiting • Phase not applicable • Cardiology / Cardiovascular • NCT05376267.…
08 Apr 2026 NCT05376267
● Recruiting Cardiology / Cardiovascular
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial is Recruiting • Phase not applicable • Cardiology / Cardiovascular • NCT05378347. The purpose of…
08 Apr 2026 NCT05378347
● Recruiting Phase III Oncology
Beamion LUNG-3: A Study to Test Whether Zongertinib Helps People With Surgically Removed, Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment
Beamion LUNG-3: A Study to Test Whether Zongertinib Helps People With Surgically Removed, Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment…
08 Apr 2026 NCT07195695
● Recruiting Phase I Oncology
A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors
A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced…
08 Apr 2026 NCT06188520
● Recruiting Phase I Oncology
Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer is Recruiting • Phase I • Oncology • NCT07181161. The…
08 Apr 2026 NCT07181161
● Recruiting Phase III Oncology
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial…
08 Apr 2026 NCT06989112