Oncology Cardiology / Cardiovascular Respiratory / COPD / Asthma Infectious Disease Gastroenterology Diabetes / Metabolic Neurology Rheumatology Women's Health Mental Health / Psychiatry Dermatology Rare Diseases Men's Health
Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

1963 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

1963 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

active not recruiting Phase III Oncology
A Study to Compare ABP 234 and Keytruda® (Pembrolizumab) in Participants With Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer
Trial comparing a biosimilar copy of Keytruda with the original drug in advanced lung cancer patients to confirm equivalent effectiveness.
21 Apr 2026 NCT06311721
active not recruiting Phase I / Phase II Oncology
Durvalumab and Tremelimumab for Pediatric Malignancies
Study testing safe doses of two immunotherapy drugs in children with advanced cancers, then checking if they work.
21 Apr 2026 NCT03837899
active not recruiting Phase III Gastroenterology
A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn’s Disease
Guselkumab (IL-23 inhibitor) tested for treating perianal fistulas in Crohn's disease patients, measuring effectiveness and safety.
21 Apr 2026 NCT05347095
● Recruiting
Impact of CMG vs VCMG in Recurrent Stress Incontinence- A Pilot Study
A pilot study comparing standard urodynamic testing versus video-urodynamic testing to guide surgery for women with recurrent stress incontinence after previous failed surgery.
21 Apr 2026 NCT07542080
● Recruiting Respiratory / COPD / Asthma
Children’s Health, Respiratory Inflammation and Short-term Air Pollution
What is being tested: Whether physical activity during periods of high air pollution exposure causes greater respiratory inflammation in children compared to remaining at…
21 Apr 2026 NCT07431021
● Recruiting Phase III Oncology
A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation
Treatment being tested: Saruparib (AZD5305), a PARP inhibitor, combined with standard radiotherapy and androgen deprivation therapy versus placebo in men with high-risk and very…
21 Apr 2026 NCT06952803
● Recruiting Neurology
Large Language Model for Understanding and Monitoring Elderly Neurocognition
What is being tested: A large language model (AI system) designed to analyse collateral histories from family members and caregivers to help understand and…
21 Apr 2026 NCT07347431
● Recruiting Phase III Neurology
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer’s Disease (ADEPT-5)
Treatment being tested: KarXT + KarX-EC combination therapy, a novel muscarinic M1/M4 receptor agonist approach, being evaluated specifically for psychosis symptoms in Alzheimer's disease…
21 Apr 2026 NCT06947941
● Recruiting Phase III Respiratory / COPD / Asthma
Randomised Evaluation of COVID-19 Therapy
What is being tested: RECOVERY is evaluating multiple therapeutic interventions (antivirals, immunomodulators, corticosteroids, and other agents) in hospitalised pneumonia patients, with the primary aim…
21 Apr 2026 NCT04381936
● Recruiting Cardiology / Cardiovascular
Atrial Functional Mitral Regurgitation and Tricuspid Regurgitation
What is being tested: This prospective observational study evaluates clinical phenotypes and predictive factors for functional mitral and tricuspid regurgitation in atrial fibrillation patients,…
21 Apr 2026 NCT05920824
● Recruiting Oncology
Bronchoscopic Microwave Ablation of Lung Tissue in Surgical Candidates – UK
Device being tested: The Creo Medical MicroBlate Flex instrument delivers microwave energy via bronchoscopy to ablate (heat and destroy) lung tumour tissue in patients…
21 Apr 2026 NCT06869122
● Recruiting Phase III Oncology
AZD0486 1L Therapy for Elderly or Unfit Participants With LBCL
What is being tested: The trial compares R-mini-CHOP chemotherapy (2 cycles) followed by AZD0486 versus standard R-mini-CHOP (6 cycles) as first-line treatment for large…
21 Apr 2026 NCT07215585
● Recruiting Phase I Oncology
AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.
What is being tested: AZD3470, an investigational oral agent, is being evaluated as both a standalone treatment and in combination with other anticancer drugs…
21 Apr 2026 NCT06137144
● Recruiting Phase III Oncology
SUPRAME-ACTengine® IMA203 vs. Investigator’s Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma
Treatment Being Tested: IMA203, a novel immunotherapy agent, is being compared against investigator's choice of standard treatments (such as checkpoint inhibitors or chemotherapy) in…
21 Apr 2026 NCT06743126
● Recruiting Phase II Rheumatology
A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)
Tulisokibart (MK-7240) is being tested to see if it can improve symptoms of radiographic axial spondyloarthritis better than placebo.
20 Apr 2026 NCT07133633
active not recruiting Phase III Cardiology / Cardiovascular
A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) – ACCLAIM-Lp(a)
Lepodisiran injection reduces heart attacks and strokes in patients with high lipoprotein(a) levels and existing heart disease.
20 Apr 2026 NCT06292013
active not recruiting Phase II
Extended Access of Momelotinib in Adults With Myelofibrosis
Momelotinib Extended Access Trial Summary This study provides ongoing access to momelotinib for myelofibrosis patients and monitors long-term safety and survival.
20 Apr 2026 NCT03441113
active not recruiting
The Use of DXA in Scoliosis
Pilot study testing whether lying-down DXA scans can accurately measure scoliosis curves and help with brace design compared to standard standing X-rays.
20 Apr 2026 NCT06512038
active not recruiting
Single Palatal Temporary Anchorage Device for Anterior Open Bite
A single palatal screw was as effective as two cheek screws for closing open bites using fixed braces.
20 Apr 2026 NCT04419805
active not recruiting Phase I / Phase II
Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)
BION-1301 was tested for safety and tolerability in healthy people and IgA kidney disease patients.
20 Apr 2026 NCT03945318
● Recruiting Phase III Oncology
A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).
What is being tested: PF-06821497 (mevrometostat), a novel investigational medicine, combined with enzalutamide versus standard treatments (enzalutamide alone or docetaxel chemotherapy) in men with…
20 Apr 2026 NCT06551324
● Recruiting Phase I Oncology
A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer
What is being tested: RO7656594, a novel investigational agent, is undergoing evaluation for its safety profile, tolerability, pharmacokinetics (drug behaviour in the body), and…
20 Apr 2026 NCT05800665
● Recruiting Phase III Oncology
Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)
What is being tested: Capivasertib (AKT inhibitor) combined with CDK4/6 inhibitors and fulvestrant compared to CDK4/6 inhibitors and fulvestrant alone in advanced/metastatic HR+/HER2- breast…
20 Apr 2026 NCT04862663
● Recruiting Phase II Oncology
A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
What is being tested: Novel therapeutic interventions and their combinations for colorectal cancer treatment, with primary focus on evaluating safety profiles and clinical efficacy…
20 Apr 2026 NCT06792695
● Recruiting Phase II Rheumatology
Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V
What is being tested: Iptacopan (LNP023), a complement factor B inhibitor, is being evaluated as an add-on therapy to standard care in patients with…
20 Apr 2026 NCT05268289
● Recruiting Phase III Respiratory / COPD / Asthma
Outpatient Treatment With Anti-Coronavirus Immunoglobulin
What is being tested: A single infusion of anti-COVID-19 hyperimmune intravenous immunoglobulin (hIVIG) compared to placebo in recently diagnosed COVID-19 patients, evaluating both safety…
20 Apr 2026 NCT04910269
● Recruiting Respiratory / COPD / Asthma
GEneRating Mucosal Immunity After INfluenzA Infection and Vaccination in Lung and Lymphoid TissuE
What is being tested: This study compares mucosal immune responses in the upper and lower respiratory tract following nasal-spray live-attenuated influenza vaccine (LAIV) versus…
20 Apr 2026 NCT06620185
● Recruiting Phase III Oncology
DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy
What is being tested: Obrixtamig (a DLL3-targeting agent) combined with atezolizumab, carboplatin, and etoposide versus standard chemotherapy alone in adults with advanced small cell…
20 Apr 2026 NCT07472517
● Recruiting Phase I Oncology
A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib as a Single Agent or in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation
What is being tested: Divarasib, a KRAS G12C inhibitor, is being evaluated as monotherapy and in combination regimens for safety, pharmacokinetics, and anti-tumour activity…
20 Apr 2026 NCT05789082
● Recruiting Phase I Oncology
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
What is being tested: PF-08046054/SGN-PDL1V, a novel therapeutic agent, is being evaluated for safety and tolerability both as monotherapy and in combination with pembrolizumab…
20 Apr 2026 NCT05208762
● Recruiting Cardiology / Cardiovascular
Graft Failure and Consequences of Coronary Artery Bypass Graft Surgery
What is being tested: This research investigates graft failure mechanisms in coronary artery bypass graft (CABG) surgery, examining why arterial and venous grafts used…
20 Apr 2026 NCT06800430
● Recruiting Phase III Oncology
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
What is being tested: Sotorasib (a KRAS G12C inhibitor) combined with platinum doublet chemotherapy versus pembrolizumab (PD-L1 inhibitor) combined with platinum doublet chemotherapy as…
20 Apr 2026 NCT05920356
● Recruiting Phase I Oncology
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma
What is being tested: Combination therapies pairing bispecific antibodies (mosunetuzumab or glofitamab) with cereblon E3 ligase modulators (CELMoDs: CC-220 and/or CC-99282) to evaluate safety,…
20 Apr 2026 NCT05169515
● Recruiting Phase I Oncology
A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation
What is being tested: BAY3498264 combined with sotorasib in patients with advanced solid cancers carrying KRASG12C mutations, investigating whether combination therapy improves efficacy beyond…
20 Apr 2026 NCT06659341
● Recruiting Phase I Oncology
Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
VIR-5500 (AMX-500) is a novel therapeutic agent undergoing evaluation for safety, pharmacokinetics, and efficacy in prostate cancer, progressing from initial dose escalation as monotherapy…
20 Apr 2026 NCT05997615
● Recruiting Phase II Women's Health
A Phase 2 Trial to Investigate Efficacy and Safety of Vipoglanstat in Women With Endometriosis
A study testing whether vipoglanstat reduces pelvic pain in women with endometriosis, beyond pain linked to periods.
17 Apr 2026 NCT07260669
active not recruiting Phase II
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy
Trial testing whether BI 764524 injection helps moderate-to-severe diabetic retinopathy, comparing different dosing schedules against sham control.
17 Apr 2026 NCT06321302
active not recruiting Phase III Diabetes / Metabolic
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
Weekly semaglutide injections tested against placebo over 5 years to see if it helps fatty liver disease.
17 Apr 2026 NCT04822181
active not recruiting Phase I Oncology
Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors
A study testing a new oral drug (MOMA-313) in patients with advanced cancers, assessing safety, dosage, and effectiveness alone or combined.
17 Apr 2026 NCT06545942
● Recruiting Phase I
A Study to Evaluate ALN-4285 in Adult Healthy Volunteers
ALN-4285 safety, tolerability, and how the body processes single doses tested in healthy adults.
17 Apr 2026 NCT07295717
active not recruiting Neurology
Psilocybin in Functional Neurological Disorder
Single psilocybin dose with therapy may alter brain network activity in functional neurological disorder patients.
17 Apr 2026 NCT05723276
● Recruiting Phase I / Phase II
A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia
Phase 1/2 trial testing oral pirtobrutinib for immune thrombocytopenia, evaluating safety, tolerability, and effectiveness at different doses.
17 Apr 2026 NCT06721013
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
What is being tested: Finerenone (a non-steroidal mineralocorticoid receptor antagonist) efficacy, safety, and pharmacokinetics in children with heart failure and left ventricular systolic dysfunction,…
17 Apr 2026 NCT07188805
● Recruiting Phase II Oncology
NEOadjuvant PembRolizumab In Stratified Medicine – ColoRectal Cancer
What is being tested: Neoadjuvant pembrolizumab (an anti-PD-1 immunotherapy) combined with standard chemotherapy and/or radiotherapy in stratified cohorts of early-stage colorectal cancer patients, assessed…
17 Apr 2026 NCT05197322
● Recruiting Phase I Oncology
A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment BNT327 and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer
Treatment Being Tested: BNT314 (immunotherapy) combined with BNT327 (immune checkpoint inhibitor) and chemotherapy in a randomised, multi-site design to evaluate efficacy and safety in…
17 Apr 2026 NCT07079631
● Recruiting Phase I Oncology
A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer
Treatment being tested: BNT323 combined with BNT327 (both investigational agents) to determine optimal dosing, safety profile, and clinical efficacy in advanced breast cancer across…
17 Apr 2026 NCT06827236
● Recruiting Phase II Neurology
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer’s Disease Dementia
What is being tested: EXV-802 and EXV-801 are novel investigational agents being evaluated for their safety and efficacy in treating agitation symptoms in patients…
17 Apr 2026 NCT07284472
● Recruiting Phase II Oncology
Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer
What is being tested: Novel immunomodulators administered as monotherapy and in combination with anticancer agents to evaluate their efficacy, safety, and tolerability in advanced…
17 Apr 2026 NCT05775159
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria
Treatment being tested: Finerenone (a non-steroidal mineralocorticoid receptor antagonist) in combination with ACE inhibitors or angiotensin receptor blockers in children with chronic kidney disease…
17 Apr 2026 NCT05196035
● Recruiting Phase II Diabetes / Metabolic
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
What is being tested: LY3457263, a novel investigational agent, is being evaluated as an add-on therapy to semaglutide or tirzepatide in patients whose blood…
17 Apr 2026 NCT06897475