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Trial Radar • ClinicalTrials.gov • Registry-linked

Trial Radar

2236 clinical trials with phase, status, specialty and registry links, summarised for rapid clinical review.

2236 recruiting AI clinical summaries
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All Phases Phase I Phase II Phase III Phase IV
Therapeutic Area: All Cardiology / Cardiovascular Dermatology Diabetes / Metabolic Gastroenterology Haematology Infectious Disease Men's Health Mental Health / Psychiatry Nephrology Neurology Oncology Rare Diseases
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Trial Radar

Clinical Trial Intelligence

● Recruiting Phase III Oncology
DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy
What is being tested: Obrixtamig (a DLL3-targeting agent) combined with atezolizumab, carboplatin, and etoposide versus standard chemotherapy alone in adults with advanced small cell…
20 Apr 2026 NCT07472517
● Recruiting Phase I Oncology
A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib as a Single Agent or in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation
What is being tested: Divarasib, a KRAS G12C inhibitor, is being evaluated as monotherapy and in combination regimens for safety, pharmacokinetics, and anti-tumour activity…
20 Apr 2026 NCT05789082
● Recruiting Phase I Oncology
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
What is being tested: PF-08046054/SGN-PDL1V, a novel therapeutic agent, is being evaluated for safety and tolerability both as monotherapy and in combination with pembrolizumab…
20 Apr 2026 NCT05208762
● Recruiting Cardiology / Cardiovascular
Graft Failure and Consequences of Coronary Artery Bypass Graft Surgery
What is being tested: This research investigates graft failure mechanisms in coronary artery bypass graft (CABG) surgery, examining why arterial and venous grafts used…
20 Apr 2026 NCT06800430
● Recruiting Phase III Oncology
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
What is being tested: Sotorasib (a KRAS G12C inhibitor) combined with platinum doublet chemotherapy versus pembrolizumab (PD-L1 inhibitor) combined with platinum doublet chemotherapy as…
20 Apr 2026 NCT05920356
● Recruiting Phase I Oncology
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma
What is being tested: Combination therapies pairing bispecific antibodies (mosunetuzumab or glofitamab) with cereblon E3 ligase modulators (CELMoDs: CC-220 and/or CC-99282) to evaluate safety,…
20 Apr 2026 NCT05169515
● Recruiting Phase I Oncology
A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation
What is being tested: BAY3498264 combined with sotorasib in patients with advanced solid cancers carrying KRASG12C mutations, investigating whether combination therapy improves efficacy beyond…
20 Apr 2026 NCT06659341
● Recruiting Phase I Oncology
Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
VIR-5500 (AMX-500) is a novel therapeutic agent undergoing evaluation for safety, pharmacokinetics, and efficacy in prostate cancer, progressing from initial dose escalation as monotherapy…
20 Apr 2026 NCT05997615
● Recruiting Phase II Women's Health
A Phase 2 Trial to Investigate Efficacy and Safety of Vipoglanstat in Women With Endometriosis
A study testing whether vipoglanstat reduces pelvic pain in women with endometriosis, beyond pain linked to periods.
17 Apr 2026 NCT07260669
active not recruiting Phase II
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy
Trial testing whether BI 764524 injection helps moderate-to-severe diabetic retinopathy, comparing different dosing schedules against sham control.
17 Apr 2026 NCT06321302
active not recruiting Phase III Diabetes / Metabolic
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
Weekly semaglutide injections tested against placebo over 5 years to see if it helps fatty liver disease.
17 Apr 2026 NCT04822181
active not recruiting Phase I Oncology
Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors
A study testing a new oral drug (MOMA-313) in patients with advanced cancers, assessing safety, dosage, and effectiveness alone or combined.
17 Apr 2026 NCT06545942
● Recruiting Phase I
A Study to Evaluate ALN-4285 in Adult Healthy Volunteers
ALN-4285 safety, tolerability, and how the body processes single doses tested in healthy adults.
17 Apr 2026 NCT07295717
active not recruiting Neurology
Psilocybin in Functional Neurological Disorder
Single psilocybin dose with therapy may alter brain network activity in functional neurological disorder patients.
17 Apr 2026 NCT05723276
● Recruiting Phase I / Phase II
A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia
Phase 1/2 trial testing oral pirtobrutinib for immune thrombocytopenia, evaluating safety, tolerability, and effectiveness at different doses.
17 Apr 2026 NCT06721013
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
What is being tested: Finerenone (a non-steroidal mineralocorticoid receptor antagonist) efficacy, safety, and pharmacokinetics in children with heart failure and left ventricular systolic dysfunction,…
17 Apr 2026 NCT07188805
● Recruiting Phase II Oncology
NEOadjuvant PembRolizumab In Stratified Medicine – ColoRectal Cancer
What is being tested: Neoadjuvant pembrolizumab (an anti-PD-1 immunotherapy) combined with standard chemotherapy and/or radiotherapy in stratified cohorts of early-stage colorectal cancer patients, assessed…
17 Apr 2026 NCT05197322
● Recruiting Phase I Oncology
A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment BNT327 and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer
Treatment Being Tested: BNT314 (immunotherapy) combined with BNT327 (immune checkpoint inhibitor) and chemotherapy in a randomised, multi-site design to evaluate efficacy and safety in…
17 Apr 2026 NCT07079631
● Recruiting Phase I Oncology
A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer
Treatment being tested: BNT323 combined with BNT327 (both investigational agents) to determine optimal dosing, safety profile, and clinical efficacy in advanced breast cancer across…
17 Apr 2026 NCT06827236
● Recruiting Phase II Neurology
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer’s Disease Dementia
What is being tested: EXV-802 and EXV-801 are novel investigational agents being evaluated for their safety and efficacy in treating agitation symptoms in patients…
17 Apr 2026 NCT07284472
● Recruiting Phase II Oncology
Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer
What is being tested: Novel immunomodulators administered as monotherapy and in combination with anticancer agents to evaluate their efficacy, safety, and tolerability in advanced…
17 Apr 2026 NCT05775159
● Recruiting Phase III Cardiology / Cardiovascular
A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria
Treatment being tested: Finerenone (a non-steroidal mineralocorticoid receptor antagonist) in combination with ACE inhibitors or angiotensin receptor blockers in children with chronic kidney disease…
17 Apr 2026 NCT05196035
● Recruiting Diabetes / Metabolic
Determining the Effect of Food Ordering on Blood Glucose In Gestational Diabetes Mellitus (DEFI-GDM)
What is being tested: The trial investigates whether the order of macronutrient consumption (carbohydrates, proteins, fats) during meals affects postprandial blood glucose levels in…
17 Apr 2026 NCT06896799
● Recruiting Phase II Diabetes / Metabolic
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
What is being tested: LY3457263, a novel investigational agent, is being evaluated as an add-on therapy to semaglutide or tirzepatide in patients whose blood…
17 Apr 2026 NCT06897475
● Recruiting Phase IV Diabetes / Metabolic
A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)
What is being tested: Tirzepatide (a dual GIP/GLP-1 receptor agonist) versus standard obesity care in a real-world UK setting, measuring weight loss and type…
17 Apr 2026 NCT07247084
● Recruiting Diabetes / Metabolic
Real-World Study of Patients With Type 1 Diabetes Treated With Teplizumab as Part of Managed Access Programs (MAPs)
What is being tested: Teplizumab, an anti-CD3 monoclonal antibody, is being evaluated in real-world clinical practice through managed access programs to assess its effectiveness…
17 Apr 2026 NCT07457580
● Recruiting Cardiology / Cardiovascular
Post-Market Celect Platinum Vena Cava Filter and Gunther Tulip Retrieval Set Study
What is being tested: Real-world safety and performance data collection for two vena cava filter devices—the Celect Platinum Filter Sets and the Günther Tulip…
17 Apr 2026 NCT05881798
● Recruiting Phase III Cardiology / Cardiovascular
Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease
What is being tested: Orforglipron, a once-daily treatment, is being evaluated for its efficacy and safety in managing Fontaine II peripheral arterial disease (symptomatic…
17 Apr 2026 NCT07223593
● Recruiting Phase III Cardiology / Cardiovascular
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
What is being tested: AZD0780, an oral PCSK9 inhibitor, is being evaluated in a Phase III randomized controlled trial to assess its efficacy in…
17 Apr 2026 NCT07000357
● Recruiting Phase III Cardiology / Cardiovascular
A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)
What is being tested: Orforglipron (LY3502970), a GLP-1 receptor agonist, is being evaluated for its effects on cardiovascular outcomes compared to placebo over approximately…
17 Apr 2026 NCT07241390
● Recruiting Cardiology / Cardiovascular
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
What is being tested: A novel atrioventricular interval modulation (AVIM) algorithm integrated into dual-chamber pacemakers to evaluate its safety and effectiveness as a potential…
17 Apr 2026 NCT06059638
● Recruiting Phase I Oncology
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
What is being tested: BNT329, an investigational drug designed to target CA19-9-expressing advanced solid tumors, with primary focus on establishing safety profile and optimal…
17 Apr 2026 NCT07186842
● Recruiting Oncology
SPECTA: Screening Cancer Patients for Efficient Clinical Trial Access
What is being tested: SPECTA is a standardized biobank platform collecting high-quality annotated biological samples, imaging data, operative records, and patient-reported outcomes from cancer…
17 Apr 2026 NCT02834884
● Recruiting Phase I Oncology
A First-in-human Study to Learn How Safe BAY 3713372 is and How it Works in Participants With MTAP-deleted Solid Tumors
BAY 3713372 is a novel PRMT5 inhibitor being tested in a first-in-human trial to treat MTAP-deleted solid tumors, designed to selectively target cancer cells…
17 Apr 2026 NCT06914128
● Recruiting Phase III Oncology
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
Intervention being tested: Vepugratinib (LY3866288), a novel therapeutic agent, is being evaluated against placebo in a randomised controlled trial to assess safety, tolerability, and…
17 Apr 2026 NCT07218380
● Recruiting Phase III Oncology
Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia
A new drug combination tested against standard treatment in older adults with newly diagnosed acute lymphoblastic leukaemia.
16 Apr 2026 NCT04994717
active not recruiting Phase III Dermatology
Study With Elranatamab Versus Lenalidomide in Patients With Newly Diagnosed Multiple Myeloma After Transplant
Elranatamab injections compared to lenalidomide tablets for newly diagnosed myeloma patients after stem cell transplant.
16 Apr 2026 NCT05317416
active not recruiting Phase III
Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)
New drug combination (sonrotoclax plus zanubrutinib) tested against standard treatment (venetoclax plus obinutuzumab) for chronic lymphocytic leukaemia.
16 Apr 2026 NCT06073821
● Recruiting Gastroenterology
Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
Implanted spinal port safely delivers nusinersen treatment to spinal muscular atrophy patients over 12 months.
16 Apr 2026 NCT05866419
● Recruiting Phase III
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Researchers tested whether a new migraine drug (BHV-3000) works better than placebo for treating severe migraines in young people.
16 Apr 2026 NCT04649242
● Recruiting Phase III
Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B
CSL222 Trial Summary CSL222 gene therapy tested in teenage boys with moderate-to-severe hemophilia B for safety, tolerability, and effectiveness.
16 Apr 2026 NCT07080905
active not recruiting Phase III Oncology
A Study to Learn More About How Well Elinzanetant Works and How Safe it is Compared to Placebo for the Treatment of Hot Flashes Caused by Anti-cancer Therapy in Women With, or at High Risk for Developing Hormone-receptor Positive Breast Cancer
Elinzanetant reduces hot flashes from cancer therapy in breast cancer patients better than placebo.
16 Apr 2026 NCT05587296
active not recruiting Phase III Oncology
Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib
Patients benefiting from olaparib in previous cancer trials can continue receiving it under this extension study.
16 Apr 2026 NCT04421963
● Recruiting Phase III
Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)
What is being tested: Ravulizumab, a complement C5 inhibitor, is being evaluated against placebo for its ability to reduce proteinuria and slow decline in…
16 Apr 2026 NCT06291376
● Recruiting Phase III Respiratory / COPD / Asthma
A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn’s Disease (CD)
What is being tested: Long-term safety and efficacy of vedolizumab (an anti-α4β7 integrin monoclonal antibody) as maintenance therapy in paediatric patients with moderate-to-severe ulcerative…
16 Apr 2026 NCT05442567
● Recruiting Phase III Oncology
JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer
What is being tested: A comparison of stereotactic ablative radiotherapy (SAbR) versus surgical sublobar resection (SR) to determine which approach provides superior survival outcomes…
16 Apr 2026 NCT02468024
● Recruiting Phase III Oncology
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)
What is being tested: Elranatamab, a bispecific antibody targeting BCMA and CD3, is being evaluated against standard treatments in relapsed/refractory multiple myeloma (RRMM) patients…
16 Apr 2026 NCT06152575
● Recruiting Phase I Cardiology / Cardiovascular
A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma
Treatment Being Tested: Sonrotoclax (BGB-11417), a BCL2 inhibitor, evaluated as monotherapy and combined with established myeloma regimens (carfilzomib, daratumumab, or pomalidomide) in relapsed/refractory multiple…
16 Apr 2026 NCT04973605
● Recruiting Phase III Cardiology / Cardiovascular
Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD
What is being tested: Pelacarsen (TQJ230), an antisense oligonucleotide therapy designed to lower lipoprotein(a) (Lp(a)), is being evaluated for efficacy and safety in patients…
16 Apr 2026 NCT06813911
● Recruiting Phase III Oncology
A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
What is being tested: Sacituzumab tirumotecan (MK-2870), an antibody-drug conjugate, as maintenance therapy either alone or combined with bevacizumab, compared to standard of care…
16 Apr 2026 NCT06824467